Institut Catala de Retina, Barcelona, Spain


To describe the characteristics of chronic central serous chorioretinopathy (CCSC) with a long duration of follow-up.


Retrospective analysis of patients diagnosed of CCSC between 2011 and 2014 with foveal involvement and follow-up of at least one year.


We included 45 patients (48 eyes) of 233 cases of central serous chorioretinopathy (39.5%). Mean follow-up was 20 months. 76.5% were men. The mean age was 50.8 ± 12.2 years with a significant difference (p<0.05) among men (47.9 ± 10.1) and women (59.8 ± 13.1). In only 28.6%of the cases association with risk factors was found. The initial visual acuity (VA) and central foveal thickness (CFT) were 0.8 and 422± 116.5 microns, respectively. The most common fluorescein angiographic pattern was a pinpoint leak (53.1%). Mean duration of the first episode was 11 months. Recurrence and chronicity were observed in 31.3%, in both cases. Final VA and CFT were 0.9 and 276 ± 50 microns, respectively. The treated group (9 cases – 18.8%) had longer evolution of episode when compared with the untreated group: 532 vs. 298 days, respectively (p <0.001). Moreover, in the treated group final VA was lower: 0.8 vs 0.9, and higher rate of chronicity was observed: 55.6% vs. 25%, but these differences were not statistically significant. In addition, no significant differences were found in anatomic outcomes. Photodynamic therapy was the most used treatment (in 3 cases as the only option and in 3 cases combined with intravitreal injections of anti-VEGF).


Functional and anatomical results of CCSC are satisfactory despite the high rate of chronicity and recurrence. Treatment seems beneficial, in long-term cases with low VA.

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Agnieszka Dyrda