SCIENTIFIC POSTER_Jesus Zarallo Gallardo

Pseudophakic cystoid macular edema is a condition presenting after complicated or even uncomplicated cataract surgery. Although it can be subclinic in many cases and self-limited, sometimes it is a recalcitrant disease that limits the results of an otherwise perfect surgery. The therapeutical options for this edema include oral acetazolamide, sub-Tenon corticosteroid injection, intravitreal corticosteroids or anti-VEGF and surgery. We present a series of 5 cases of pseudophakic cystoid macular edema that were treated with a single injection of a dexamethasone implant (Ozurdex). There were two men and three women whose age ranged between 66 to 91 years-old (mean 76 y/o). One of the patients had a retained nuclear fragment in the anterior chamber that required a second surgery and other patient needed an intraoperative intraocular lens exchange due to a power mistake. The other three patients had uncomplicated cataract surgery. The time from phacoemulsification and treatment ranged between 4 and 8 months (mean 5.8 months). Mean central macular thickness at the time of injection was 517.6 microns (range 743-341 microns). Visual acuity at the time of injection ranged from 0.20 to 0.54 (logMAR 0.32-0.7), with a mean visual acuity of 0.31 (logMAR 0.62). After treatment there was a dramatic improvement in central macular thickness, reaching a mean thickness of 251.8 microns at month two post-injection. This improvement was maintained over the next six months. Similarly, visual acuity improved from the initial 0.31 to 0.62 at month two, and continued improving up to month six. Only one patient lost visual acuity after the initial improvement due to the development of persistent corneal edema. This patient was the oldest of the series (91 y/o) and was the one that suffered from the intraoperative IOL exchange. No complications were reported after the treatment and none of the patients needed additional injections. The injection of a single dexamethasone implant into the vitreous is a safe and effective treatment for pseudophakic cystoid macular edema.