Vitrectomy for Endophthalmitis in 119 Eyes at Ophthalmic Hospital of Rome (Italy) from 2011 to 2016



This is a prospective study to evaluate the causes and the outcomes of endophthalmitis arrived at the First Aid of the Ophthalmic Hospital of Rome between January 2011 and December 2016. We search the germs involved, we analysed the time between the diagnosis and the surgical treatment and we have evaluated the final visual acuity. We try to see if there was a correlation between the germ involved and the final visual acuity, and if there was a correlation between the time of the diagnosis and the surgical treatment and the final visual acuity.


All the patients with a visual acuity under 20/200 were submitted to pars plana vitrectomy. We performed a aqueous and vitreous humor sampling for microbiological analysis, and an injection of intravitreal vancomycin 0,1 cc (10 mg/ml) and ceftazidime 0,1 (22,5 mg/ml) was also done. We save in all cases the capsular bag and the intraocular lens and we use silicone oil tamponade in mostly cases.


The most common germs involved were staphylococcus epidermidis, staphylococcus hominis and streptococcus pneumoniae. 55% of the endophthalmitis were secondary to a phacoemulsification surgery, 10% were due to a blebitis and 7% to a trauma, the residual cases to other cause. The statistical results have shown that the best functional results were in the cases when the surgery was performed within 24 hours from the diagnosis. We did not find statistically significant differences between the involved germ and the final visual recovery and we did not find any differences depending on the month of onset of endophthalmitis.


To have an useful and acceptable visual result, a prompt diagnosis and an early vitrectomy within 24/48 hours from the time of diagnosis are mandatory.


Paolo Michieletto
Rome, Italy
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