Ulrike Stolba, MD, Susanne Binder, MD, Diego Gruber, PhD, Ilse Krebs, MD, Beatrix Neumaier, MD, Dept. of Ophthalmology and Boltzman Institute for Retinology and Biomicoscopical Laser Surgery, Rudolf Foundation, Vienna, Austria

Purpose:

To evaluate the potential benefit of vitrectomy in eyes with diffuse macular edema compared to an unoperated control group.

Methods:

56 eyes with diffuse diabetic edema and attached posterior hyloid were randomized into an operation group I (25 eyes) and a control group II (31 eyes). Vitrectomy was combined with ILM-peeling. All eyes were followed for 6 months. Parameters of interest were visual acuity for far and near as well as OCT measurements.

Results:

After 6 months 52% in the operation group as against 13% in the control group showed an increased ETDRS vision. There were statistically significant better results for operated eyes during follow up. At this time 40% of the operated eyes compared to 10% of the controlled eyes achieved a better reading vision. Statistical significance was only found
for the final results. The retinal thickness decreased after 6 months to an average of 480µ (range 268 to 722) in the operation group and to 577µ (range 425 to 724) in the control group. There was a significant decrease after 1 month in the operated eyes.

Take-home message:

Vitrectomy in eyes with diffuse diabetic edema shows statistically significant better results for far visual acuity (all time points) and near visual acuity (at 6 months) compared to an unoperated control group. However, the increase is not significant.