http://www.evrs.eu/medias/2009/congress/Retinal-Vein-Occlusions.flv

Authors: Masoud Soheilian, Alireza Ramezani, Ali Tavallali, Mohammad R. Mohebbi, Gholam A. Peyman, Tehran, Iran

Advantages:

Four treatment methods for central retinal vein occlusion (CRVO) were compared with its natural course.

Methods:

In this partially prospective, comparative, interventional case series on 63 eyes with CRVO, five approaches were compared: intravitreal triamcinolone (IVT) injection (14 eyes), radial optic neurotomy (RON) (13 eyes), combined RON and intraocular triamcinolone injection (RON/IVT) (10 eyes), combined RON, IVT and internal limiting membrane (ILM) peeling,  (ILM peeling/RON/IVT) (12 eyes), and observation (14 cases).

Effectiveness / Safety:

Final visual acuity (VA) in the IVT group was better compared with the observation group (P=0.025), and the RON (P=0.037), RON/IVT (P=0.401), and ILM peeling/RON/IVT (P=0.023) groups. However, after adjustment for baseline VA, the only treatment method with significant VA improvement in relation to observation was RON/IVT (P=0.025, P=0.023, and P=0.054 at months 1, 3, and 6, respectively).

Take home message:

Among five different approaches analyzed in this study, RON/IVT may provide a better visual outcome in the management of CRVO.