Mahmoud Soliman, (Cairo, Egypt)


To describe the development and behaviour of full thickness macular holes in patients with Best Vitelliform Macular Dystrophy (BVMD) and Behcets disease.


The study includes six male and one female patients with an average age of 35 (range; 30-40). Three cases of Best Vitelliform Macular Dystrophy, clinically and electrophysiologically confirmed diagnosis, and four cases of Behcets disease were observed to develop full thickness macular holes. None of the patients had myopic eyes or history of trauma. The clinical features and prognosis of their macular holes are described.


In BVMD full thickness macular hole developed at stages 3, followed by retinal detachments localized to posterior pole with clear fluids subretinal fluids. In behcets, the full thickness macular holes developed following activity with retinal vasculitis and  ischemia. All patients refused surgical intervention with the exception of one patient of the Behcet group who underwent pars plana vitrectomy with ILM peel and SF6 gas tamponade. This failed to close the the macular hole.


Full thickness macular hole can develop in unusual forms with Best Vitelliform Macular Dystrophy and Behcets disease.