Poster Barbara Delas

Objective:

To analyse the structural and functional changes in patients with macular oedema secondary to retinal vein occlusion and non-infectious posterior uveitis, twenty-four hours after the injection of a dexamethasone intravitreal implant.

Method:

6 eyes of 6 patients were analysed (3 branch retinal vein occlusion, 2 central retinal vein occlusion and 1 case of non-infectious uveitis). For each patient, age, sex, cause and duration of macular oedema and previous treatments, were considered. Best corrected visual acuity (BCVA), intraocular pressure (IOP) and foveal thickness were measured before and twenty-four hours after injection.

Results:

In 5/6 patients (83.3%) visual acuity improved from one to two lines one day after the implant. Three patients (33.3%) increased IOP between 4-6 mmhg in the first day after the implant, remaining within the bounds of normality. In one patient the pressure increased to 24 mmHg, so topical hypotensive therapy was administered. Foveal thickness decreased 150-200 microns in the first days after the implant in all cases.

Conclusions:

Despite the long curve of action of dexamethasone intravitreal implant and the peak described at two months, significant anatomical and functional changes have been observed in the first twenty-four hours after administration.