Hande Etus, Levent Karabas, Yusuf Çaglar (Kocaeli, Turkey)


To compare anatomic and functional results in patients with macular edema in central retinal vein occlusion (CRVO) treated with pars plana vitrectomy (PPV) with internal limiting membrane (ILM) peeling and intravitreal bevacizumab injection treatment (IVBT).


A total of 29 patients were examined retrospective. PPV with ILM peeling was performed in Group A (n=14). IVBT was done in Group B (n=15). All patients had a complete ocular examination, including best-corrected VA with the Snellen chart, before treatment and 1 week, 1 month, 3 months, 6 months and 12 months after the treatment, as well as fluorescein angiography and OCT before and after the treatment. The central macular thickness was defined as the distance between the vitreoretinal interface and the retinal pigment epithelium in the center of the fovea. Statistical analyses were performed using t tests and Wilcoxon tests.

Effectiveness / Safety:

Anatomic improvement, defined as a reduction of the central macular thickness was achieved in 11 patients (%78, 5) in Group A and in 9 patients (%60, 0) in Group B. No statistically significant difference (p>0, 05). VA improvement, defined as an improvement of at least of 1 Snellen line was achieved in 10 patients (%71,4) in Group A and in 6 patients (%40,0) in Group B. The difference was found to be statistically significant.