Kim, Jung-Yeul

Purpose:

To evaluate the postoperative frequency and severity of posterior synechia after combined pars plana vitrectomy, phacoemulsification, and intraocular lens implantation in different groups using long-acting and short-acting mydriatics.

Design:

Prospective, randomized, controlled trial.

Participants: A total of 69 eyes in 69 patients with rhegmatogenous retinal detachment and cataracts.

Methods:

All patients underwent a combined operation by the same surgeon.  Thirty-seven eyes were assigned randomly to the use of a long-acting mydriatic (group 1), and thirty-two eyes were assigned randomly to the use of a short-acting mydriatic (group 2) after the operation.

Main Outcome Measures:

The frequency and severity of posterior synechiua were evaluated at baseline and over a 6-month follow-up period.

Results:

Posterior synechia was seen in 11 eyes (29.7%) in the long-acting mydriatic group and in three eyes (9.4%) in the short-acting mydriatic group.  The difference was statistically significant (p=0.036).  Additionally, when the severity of the posterior synechia was measured in hour units, there was a statistically significant different in severity between the two groups (long-acting mydriatic group, 0.76 ± 1.52 h; short-acting group, 0.13 ± 0.42 h; p=0.020).

Conclusions:

The frequency and severity of posterior synechia after a combined operation can be reduced by the use of a short-acting mydriatic.