Poster Kuhl Huh

Purpose:

To investigate the influence of macular edema on visual function, central retinal thickness (CRT) was measured and microperimetry (MP) and contrast sensitivity (CS), which are functional tests of retina, were performed in diabetic macular edema (DME) patients. And the correlations among CRT, MP and CS were evaluated.

Methods:

Single center retrospective study was performed from May 2012 to August 2012. This study included 47 eyes from 36 patients with baseline central 1mm subfield retinal thickness (CRT) ≥250 um. The CRT and MP were tested by spectral SLO/SD-OCT system (OTI OCT, OPKO Instrumentation, Miami, Florida, USA). MP was tested at the macular center 2° and 4°. CS was measured with 6 target sizes (6.3°, 4.0°, 2.5°, 1.6°, 1.0°, 0.64°) with or without glare using Contrast glare tester (CGT-2000, Takagi Seiko co., Ltd., Nagano-Ken, Japan). Pearson correlations were used for analysis of correlation among the CRT, MP and CS.

Results:

Mean age was 59.53 ±10.44 years and mean best-corrected visual acuity (-LogMAR) was 0.35 ±0.22. Mean CRT was 339.3 ±134.4 um. Mean MPs at the macular center 2° and 4° were 8.92 ±4.09 dB and 9.62 ±3.83 dB. Mean CSs (-log) at 6 target sizes with or without glare were ranged from 0.20 ±0.26 to 1.35 ±0.47. The CRT showed no significant correlation with both MP and CS (p=0.762, 0.559). There were significant correlation between MP at the center 2° and CS of 0.64°, 1.0°, 1.6° targets with glare (r=0.588, 0.610, 0.631, all p=0.000) or without glare (r=0.691, 0.664, 0.625, all p=0.000). MP at the center 4° also significantly correlated with CS of 2.5°, 4.0°, 6.3° targets with glare(r=0.654, 0.669, 0.619, all p=0.000) or without glare (r=0.566, 0.491, 0.531, all p=0.000).

Conclusion:

In this study, both MP and CS were not correlated with CRT in DME. However, MP and CS were showed moderate but significant correlation.