To report the results of 23G pars plana vitrectomy (PPV) with vancomycin in tapping in endophthalmitis following intraocular surgery and eye trauma.


31 patients were treated with 23G PPV (19 due to postoperative endophthalmitis and 12 due to posttraumatic endophthalmitis) with vancomycin in tapping. All patients received topical and intravenous broad-spectrum antibiotics. Silicone oil tamponade was used in 17 cases, BSS in 14 cases. In 2 cases PPV was combined with keratoplasty and temporary keratoprosthesis. Visual acuity improved in 83% of postoperative endophthalmitis and in 75% of posttraumatic endophthalmitis. Intraocular foreign body was present in 5 cases of posttraumatic endophthalmitis. Staphylococcus aureus was the most common pathogen found in microbiological examination.

Effectiveness / Safety:

PPV combined with vancomycin in tapping represents the standard treatment for acute infectious endophthalmitis. Endophthalmitis is a serious ocular complication of open globe injury and intraocular surgery with a potential to lead to profound loss of vision. However, early PPV combined with intravitreal and systemic antibiotic treatment may lead to vision improvement.