Advantages:

To report the results of 23G pars plana vitrectomy (PPV) with vancomycin in tapping in endophthalmitis following intraocular surgery and eye trauma.

Methods:

31 patients were treated with 23G PPV (19 due to postoperative endophthalmitis and 12 due to posttraumatic endophthalmitis) with vancomycin in tapping. All patients received topical and intravenous broad-spectrum antibiotics. Silicone oil tamponade was used in 17 cases, BSS in 14 cases. In 2 cases PPV was combined with keratoplasty and temporary keratoprosthesis. Visual acuity improved in 83% of postoperative endophthalmitis and in 75% of posttraumatic endophthalmitis. Intraocular foreign body was present in 5 cases of posttraumatic endophthalmitis. Staphylococcus aureus was the most common pathogen found in microbiological examination.

Effectiveness / Safety:

PPV combined with vancomycin in tapping represents the standard treatment for acute infectious endophthalmitis. Endophthalmitis is a serious ocular complication of open globe injury and intraocular surgery with a potential to lead to profound loss of vision. However, early PPV combined with intravitreal and systemic antibiotic treatment may lead to vision improvement.