Sub-foveal Choroidal Thickness in Acute Central Serous Chorioretinopathy and its Correlation with Central Macular Thickness


ABSTRACT

Purpose:

To measure sub-foveal choroidal thickness in eyes with central serous chorioretinopathy (CSCR), to compare it with that of contralateral clinically unaffected eyes and with that of other healthy persons and to study its correlation with central macular thickness.

Design:

Prospective cross-sectional study.

Subjects & Methods:

Fifty four eyes of 36 subjects (23 males and 13 females) with a mean age of 37.69 years were included under 3 groups; 18 eyes with recent unilateral central serous chorioretinopathy, 18 free fellow eyes of patients with unilateral CSCR and 18 healthy eyes of age-matched normal controls. Spectral-domain optical coherence tomography was used to measure sub-foveal choroidal thickness (SFCT) in all eyes and central macular thickness (CMT) in eyes with CSCR. Multiple values were compared by analysis of variance (ANOVA) while correlations were investigated using Pearson correlation coefficient.

Results:

Mean patients’ age was 37.4 years while that of normal controls was 38.0 years. Mean SFCT was 332.0µ in eyes with CSCR, 247.25µ in the unaffected fellow eyes and 248.74µ in normal control eyes. SFCT in eyes with CSCR was significantly greater than each of unaffected fellow eyes (P = 0.000) and normal control eyes (P = 0.000) while there was no significant difference between fellow eyes and control eyes (P = 0.906). Mean central macular thickness, including the serous retinal detachment, in eyes with CSCR was 477.62µ with a significant positive correlation between SFCT and CMT in these eyes (r = 0.622 and P = 0.023).

Conclusions:

Spectral-domain optical coherence tomography is a noninvasive easy, reproducible tool to image the choroid. Sub-foveal choroid in eyes with acute unilateral CSCR was significantly thicker than in contralateral clinically unaffected eyes and than in healthy eyes of age-matched normal controls while it was not significantly different between contra-lateral and normal eyes. Central macular thickness was positively correlated with sub-foveal choroidal thickness in eyes with CSCR.


CONTACT DETAILS

Maha Shahin
Mansoura, Egypt
Email : mahashahin@msn.com
Cell Phone: +201001988990
Work Phone: +20502239414