Wai-Ching Lam, MD (Toronto, Canada), Feisal A. Adatia, MD (Toronto, Canada), Robert G. Devenyi, MD (Toronto, Canada)


Systemic Lupus Erythematosus (SLE) is an immune mediated multiorgan disease in which the eye is commonly involved. Serous retinal detachments (RD) are uncommon, we present three cases of serous RD with different manifestations and etiologies. Recognition of clinical characteristics and ophthalmic findings can help tailor treatment and alert clinicians as to
when SLE choroidopathy can potentially be fatal.


Case series of 3 SLE patients presented consecutively with serous retinal detachment. Patients underwent IVFA, ICG, OCT and B-Scan evaluation where appropriate.


The etiology of the 3 cases were: SLE choroidopathy, effusive retinal detachment due to SLE nephropathy and classic central serous retinopathy. A combination of immunosuppressive agents, oral and subtenon steroids were successful in treating systemic SLE manifestations as well as ocular SLE choroidopathy in one patient. A second patient with both pleural and
pericardial effusions as well as SLE nephropathy improved with resolved systemic effusions. Our third patient had classic CSR and resolved with time.


Careful attention to clinical presentation and FA, ICG angiography can help determine treatment modalities and alert clinicians as to when SLE choroidopathy can be life threatening. Serous detachments in SLE can have varied etiologies and tailored treatment is appropriate.