Purpose:

To identify the prognostic factors for visual outcome after surgical reattachment in patients with macula-off rhegmatogenous retinal detachment (RRD).

Methods:

The medical records of 28 patients (28 eyes) with macula-off RRD were retrospectively reviewed. In addition to baseline characteristics, preoperative and postoperative spectral domain optical coherence tomography images were investigated. Results: Age at the onset of RRD was 49.7±18.7 years, with mean follow-up of 13.9±18.5 months. Mean duration of symptoms was 13.9±18.5 days. Mean BCVA was 1.32±0.89 logMAR (Snellen equivalent 20/408) at baseline. Mean CMT at baseline was 914.6±492.1, and mean height of subretinal fluid was 839.4±776.5. 7 patients (25.0%) showed cystic cavities in inner nuclear layer, and 25 patients (89.3%) did in the outer nuclear layer. Undulation of separated outer retina was observed in 22 patients (78.6%), with dropout in 9 patients (40.9%). Postoperative ELM was disrupted in 5 patients (17.9%), and photoreceptor inner segment (IS)/outer segment (OS) integrity was disrupted in 13 patients (46.4%). Stepwise multiple regression analysis showed three factors for postoperative visual outcome: ELM integrity (P<0.001), height of subretinal fluid at fovea (P=0.001), and photoreceptor IS/OS junction integrity (P=0.015).

Conclusion:

Preoperative height of subretinal fluid at fovea, postoperative status of ELM and photoreceptor IS/OS junction were significantly associtaed with postoperative visual outcome in macula-off RRD patients.