Gungor Sobacı, MD, Salih Altun, MD, Yusuf Uysal, MD, M. Zeki Bayraktar, MD, Gulhane Medical Faculty Department of Ophthalmology, Ankara, Turkey


To evaluate the safety of intravitreal injection of triamcinolone acetonide for diffuse diabetic macular edema.


Forty eyes of 40 patients with diffuse diabetic macular edema were included. All were given intravitreal injection of 4mg of triamcinolone acetonide. They had no previous history of glaucoma, uveitis or steroid use. They were monitored with respect to safety from intravitreal injections throughout the follow-up period regularly.


Floaters not obscuring the central vision significantly were common complaint. In total, 45 injections were done. No endophthalmitis, damage to the lens or toxicity to the retina was observed during 3 to 12 months follow-up period. IOP elevations ranging 5 to 20mmHg were noted in 12 eyes (30%). IOP rises were controlled by glaucoma medications (1 to 3 drugs) within 2 months in the most (32 eyes, 80%).


Intravitreal injections of 4mg of triamcinolone acetonide seems to be safe. IOP elevatons are not rare and can be controlled by routine glaucoma medications.