S. Natarajan, Santosh Mahapatra, Hitendra B. Mehta , Hemant Todkar


To establish the role of R-TPA in management of massive subretinal haemorrhage due to ARMD.


Retrospective case control study.


Clearance of subretinal / sub RPE haemorrhage in two of our cases following vitrectomy and subretinal R-TPA injection.


Subretinal / Sub Retinal Pigment Epithelium (RPE) R-TPA, is a good therapeutic option in patients of massive Subretinal / Sub RPE haemorrhage due to ARMD.

Take-home message:

To try vitrectomy and subretinal R-TPA in non resolving massive subretinal bleed in patients of ARMD.