SCIENTIFIC POSTER 2016_Retinal Nerve Layer, Ganglion Cell Layer, Retinal and Subfoveal Choroidal Thickness Measured with Swept-source OCT after MH Surgery Yavuz Bardak


To evaluate the changes in retinal nerve fiber layer thickness (RNFLT), ganglion cell layer thickness (GCLT), retinal thickness (RT), and subfoveal choroidal thickness (SFCT) in eyes who received pars plana vitrectomy (PPV) with internal limiting membrane peeling (ILM) for idiopathic macular hole (IMH) and to compare this data with data from fellow eyes and healthy controls.


A total of 49 subjects were enrolled. Eighteen eyes that underwent surgery for IMH, 18 fellow eyes, and 31 eyes of the healthy controls were designated as group 1, group 2, and group 3, respectively. The RNFLT, GCLT, RT, and SFCT were measured by using the SS-OCT (The Deep Range Imaging OCT; Atlantis, Software version 9.14, Topcon, Japan) device at last postoperative visit.


The RNFLT was found to be significantly reduced in temporal, superior, and inferior quadrants in group 1 as compared to group 2 and group 3 (p<0.05). No significant difference was found in nasal RNFLT between the groups (p>0.05). There was a statistically difference of GCLT between the groups. The GCLT was lower in group 1 than group 2 and group 3 (p<0.05). After analysing the RT, it was found that RT (at each field except the central portion) was significantly lower in group 1 when compared to group 2 and group 3 (p<0.05). The SFCT was 206.33±7.94 µm (range, 191 µm to 221 µm) in group 1, 276.38±53.69 µm (range, 134 µm to 352 µm) in group 2, and 305.67±51.03 µm (range, 197 µmto 373 µm) in group 3. SFCT was significantly lower in group 1 than group 2 (p=0.001) and group 3 (p=0.001). No difference of SFCT was observed between group 2 and group 3 (p=0.006).


A reduction in the RNFLT, GCLT, RT, and SFCT was observed following PPV with ILM peeling for IMH detected by SS-OCT.

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