Retinal and Choroidal Vascular Changes in Macular Telangiectasia Type 2 on Optical Coherence Tomography Angiography



To investigate retinal and choroidal vascular changes in patients with macular telangiectesia type 2 by using spectral domain optical coherence tomography angiography (SD-OCTA).

Materials & Methods:

A cross-sectional study was conducted on 38 eyes of of 19 consecutive patients with MacTel 2. All patients underwent complete ophthalmic examination including fundus photography, spectral domain OCT and OCTA , fluorescein angiography ,EDI OCT and fundus autofluoresceine (FOF) imaging. Age and sex matched control group also underwent fundus photography, spectral domain OCT and OCTA ,EDI-OCT and FOF. Retinal capillary density and choroidal thickness were compared between patient and control group.


Foveal avascular zone was significantly larger in patient group (0.39 vs 0.33 mm2) p<0.05).Foveal vessel density was not significantly different between groups in the superficial plexus (27.12% vs. 29.14%; P >0.05) . Superficial PFVD was significantly different in the two groups (53.06% vs. 54.40%; P <0.05). Foveal retinal thickness was 232.13 μm in MacTel 2 eyes and 248.18 μm in normal controls, and PFRT was 296.60 and 319.29 μm, respectively (P < 0.001). After adjusting for age and axial length, the authors found that eyes with MacTel2 had a mean CT measurement that was greater than control eyes (P <0.05).

Discussion & Conclusion:

Optical coherence tomography angiography is useful for retinal vasculature characterization in MacTel type 2 patients. Choroidal tissue seems to be thicker in patients with MacTel type 2


Yusuf Akar
Antalya, Turkey
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