Results of Pars Plana Vitrectomy in the Management of Complicated Uveitis


Results of Pars Plana Vitrectomy in the Management of Complicated Uveitis by Hande Celiker, Haluk Kazokoglu, Turkey



To evaluate the efficacy of pars plana vitrectomy (PPV) on the preservation vision in complicated chronic uveitis.


Retrospective study of the charts of 19 uveitis patients (24 eyes) who underwent PPV between the years 2012 and 2017. We examined surgical indications and success rates based on visual outcomes, complications and diagnosis in case of vitreous biopsy. Vitreous specimens obtained via PPV were analyzed by microbiologic culture, cytologic analysis, and flow cytometry in eyes with suspected intraocular infection or malignancy.


Diagnostic PPV (DVx) was performed in 14 patients (73.7 %). Positive results indicated infectious uveitis in 7 patients (50.0 %) and lymphoma in 2 patients (14.3 %). Therapeutic PPV (TVx) was performed in 5 (26.3%) patients. TVx combined with epiretinal membrane peeling in 100 % of the cases. Statistically significant improve in visual acuity was obtained in patients with uveitis (<0.001, Friedman Test). Eight patients (42.1%) did not need any immunomodulating drug after the postoperative period. In the early postoperative period, complications were glaucoma (16,7%) retinal detachment (8,3%), hypotonia (4,2%), recurrent infection (4,2%). In the late postoperative period, complications were glaucoma (4,2%), epiretinal membrane (4,2%), hypotonia (4,2%), retinal detachment (4,2%), intraocular lens blurring (4,2%), cataract (4,2%), cystic macular oedema (4,2%).


PPV may visually rehabilitate cases with chronic uveitis, and may reduce the activity of disease postoperatively.


Hande Celiker
Istanbul, Turkey
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