ABSTRACT

Introduction:

The occurrence of a subretinal hemorrhage in age-related macular degeneration (AMD) is a serious complication that can impact the visual prognosis with a poor functional recovery. We report the results of sixteen patients treated with a protocol combining: vitrectomy, subretinal injection of r-TPA 0.025mg/0.3ml, subretinal injection of air, intravitreal injection of 0.05ml of bevacizumab and retinal tamponade with 20% SF6 gas.

Patients & Methods:

Our series consists of sixteen patients with a submacular hemorrhage complicating AMD. All patients underwent surgery within 6 weeks after the onset of the macular hemorrhage.

Results:

All patients showed a significant displacement of SMH with recovery of the normal foveal contour. Best corrected visual acuity improved in all cases. Improvement in best-corrected visual acuity by >0.3 logMAR units was obtained in 13 eyes . All cases showed changes in outer retinal layers by OCT.

Conclusion:

The therapeutic evaluation of this protocol in our series of sixteen patients gives a favorable result. We observed an improvement in visual acuity in all cases. This surgical technique appears to be effective in the treatment of this complication of AMD. It is more effective than other techniques used, But still there are changes in outer retinal layers which cannot avoid.


CONTACT DETAILS

 

Samir EL BAHA, Amir RAMADAN
Alexandria University Faculty of Medecine
Alexandria
Egypt
Email : samir_elbaha@yahoo.com
Cell Phone: +201001071891
Work Phone: +2035923211