SCIENTIFIC POSTER 2016_Outer Retinal Layers Alterations in Chronic CSCR OCT Images and Fundus Autofluorescence Findings Ji-Hye Jang


To document the alteration of the outer retinal layers and fundus autofluorescence (FAF) change in eyes with chronic central serous chorioretinopathy (CSCR).


Seventeen eyes of fifteen patients with chronic CSCR from January of 2014 to March of 2015 with at least 6 months of follow-up with non-surgical history were enrolled in the study. Morphologic alterations in the retinal pigment epithelium (RPE), the photoreceptor inner segment/outer segment (IS/OS) junction layer, outer retina were evaluated by Spectral-domain optical coherence tomography (SD-OCT). Heidelberg Retina Angiogram obtained the FAF images and the distribution patterns of retinal autofluorescence were described. After tomographic alignment of FAF intensities with OCT finding, we analyzed and assessed the alteration of the outer retinal layers and the characteristics of retinal autofluorescence.


All eyes with IS/OS junction defect, RPE atrophic lesion in SD-OCT correlate with hyper-fluorescence in FAF; RPE detachment lesion in SD-OCT shows little or no change in autofluorescence pattern. Seven of nine eyes with persistent subretinal detachment (SRD) were detected in the photoreceptor IS/OS elongation beneath neurosensory retina at SD-OCT and among those, five eyes of same lesion correlate with ring shape hyper-fluorescence in FAF.


In chronic CSCR, the lesion IS/OS junction defect, photoreceptor OS elongation, the border of SRD, RPE diffuse atrophy in SD-OCT correlate with hyper-fluorescence lesion in FAF. The areas of the autofluorescence change in FAF image are associated with the extent of permanent changes of the RPE and outer retina.

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Ji Hye Jang