ABSTRACT

Purpose:

To describe the prevalence of vitreoschisis in eyes with idiopathic vitreomacular traction (VMT) and to correlate the presence of vitreoschisis with other structural alterations detected using spectral domain optical coherence tomography (SD OCT).

Methods:

In this IRB-approved retrospective analysis, we collected data from 502 eyes with VMT from 307 patients with SD OCT imaging obtained. The presence of vitreoschisis and other structural alterations of the macula (cystoid macular edema, neuroephitelium detachment, ellipsoid zone (EZ) and external limiting membrane (ELM) discontinuity) was determined by standardized grading of macular SD OCT scans.

Results:

Of the 307 patients with VMT (502 eyes) included in this analysis, 139 were female (45.3%) and 168 were male (54.7%). Mean±SD age was 71.9±10.7 years. OCT revealed vitreoschisis in 188 (37.5%) eyes (101 patients). Mean±SD central foveal thickness was 411±60 µm in eyes with vitreoschisis and 380±148 µm in eyes without vitreoschisis (p<0.05). The presence of cystoid macular edema (38.3% vs 23.2%, p<0.05), serous neuroephitelium detachment (24.5% vs 9.9%, p<.0001), ELM discontinuity (16.5% vs 5.1%, p<.0001) and EZ discontinuity (13.3% vs 6.7%, p<.05) was increased in eyes with vitreoschisis. Mean±SD best corrected visual acuity was 0.45±0.16 LogMAR in eyes with vitreoschisis and 0.37±0.09 in eyes without vitreoschisis (p<.0001). Symptoms of metamorphopsia were present in 55 out of 188 eyes with vitreoschisis (29.3%) and 40 out 314 eyes without vitreoschisis (12.7%, p<0.0001).

Conclusions:

This study reported the prevalence of vitreoschisis in eyes with VMT and demonstrated that vitreoschisis is significantly associated with an increased occurrence of other structural changes of the neuroretina. Further longitudinal studies are necessary to elucidate the nature and extent of vitreoschisis in the prognosis of eyes with idiopathic vitreomacular traction.


CONTACT DETAILS

 

Enrico BORRELLI, Vincenzo CICIARELLI, Paolo CARPINETO*
University G. d’Annunzio Chieti-Pescara
Chieti
Italy
Email : p.carpineto@gmail.com
Cell Phone: +393662025015
Work Phone: +390871358410