To compare the optical coherence tomographic (OCT) features of naive macular edema in patients with ischemic and non-ischemic retinal vein occlusion by a different perspective.


90 eyes of 90 patients with naive macular edema due to retinal vein occlusion (66 branch retinal vein occlusion and 24 central retinal vein occlusion) who had spectral-domain OCT (Nidek RS-300, Nidek Co.,Japan) images obtained were retrospectively reviewed. All images were obtained at the time of first diagnosis before any treatment. The patients were assigned the two groups (Group 1: Ischemic, Group2: Non-ischemic) based on the fluorescein angiography findings. Group 1 had 38 eyes and Group 2 had 52 eyes. The OCT images were evaluated in terms of Disorganised retinal inner layer (DRÄ°L), external limiting membrane (ELM), foveal serous retinal detachment (SRD) and Hyperreflective foci.


The median age of Group 1 was 66(40-95),and the median age of Group 2 was 61(41-82). DRÄ°LL was present 78.4% in Group 1and 69.2% in Group 2 (p=0.238). Uninterrupted ELM was present 35.1% in Group 1and 57.7% in Group 2 (p=0.029). SRD was present 51.4% in Group 1and 53.8% in Group 2 (p=0.493). Hyperreflective foci was present 91.9% in Group 1and 98.1% in Group 2 (p=0.193).


External limiting membrane was found to significantly interrupted in ischemic retinal vein occlusion associated macular edema. ELM health, might be considered to sensitive to retinal ischemia.The poor prognosis of ultimate anatomical healing and response to treatment in ischemic macular edema may associated with interrupted ELM.



Inonu University Medical Faculty Department of Ophthalmology
Email : drnihatpolat@gmail.com
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