Mahmoud Soliman, (Cairo, Egypt)


Evaluation of the Nerve Fiber Layer (NFL) thickness lose following full scatter laser photocoagulation in diabetic patients using Optical Coherence Tomography (OCT) with its correlation to the number of laser shots.


Twenty eyes of 14 patients legible for full scatter laser photocoagulation were included in this study with an average age of 53 years (range 31-65). Male to female ratio was 8:6. Laser photocoagulation was done using standard technique. A circular OCT scan around the optic nerve head was done before laser therapy and at 1 and 3 months post laser.


Patients were subdivided into two groups; group A (n=10 eyes): received less than 2000 laser shots and group B (n=10 eyes): received more than 2000 laser shots. NFL thickness was reduced at 3 months by 21% in group A with a maximum reduction in the nasal quadrant by 38%. In group B, NFL was significantly reduced (P<0.001; t-test) at 3 months by 38%, compared to group A, with a maximum reduction in the nasal quadrant by 46% at 3 months.


Full scatter laser photocoagulation can produce substantial lose in NFL thickness reaching up to 46%.