Ozgür Bilen, Kubilhan Elmas, Ali Altýnsoy (Ankara, Turkey)


To assess the long-term safety and efficacy of intravitreal triamcinolone acetonide injection in the management of macular edema caused by branch retinal vein occlusion.


This retrospective case series included 11 patients (11 eyes) with retinal vein occlusion and macular edema. They received an intravitreal injection of 4 mg triamcinolone acetonide. Follow-up was for 1 year with repeat injections where appropriate. Outcome measures we re visual acuity and macular thickness measured using ocular coherence tomography (OCT).


Eight eyes responded well with improved visual acuity and macular thickness 1-5 months postinjection. All eight eyes developed recurrent macular edema and six received repeat injections. Two patients declined a second injection. No improvement in visual acuity or OCT macular thickness was seen after the second injection with visual acuity returning to baseline levels at 1-year follow-up. Three eyes showed no response to the initial injection (no improvement in macular thickness or visual acuity). Two patients had a rise in intraocular pressure requiring treatment.


Intravitreal injection of triamcinolone acetonide is effective as a short-term treatment of macular edema owing to retinal vein occlusion, improving both visual acuity and macular thickness. However, this effectiveness is not maintained after 1 year despite repeat injections.