Ozgür Bilen, Kubilhan Elmas, Ali Altýnsoy (Ankara, Turkey)

Purpose:

To assess the long-term safety and efficacy of intravitreal triamcinolone acetonide injection in the management of macular edema caused by branch retinal vein occlusion.

Methods:

This retrospective case series included 11 patients (11 eyes) with retinal vein occlusion and macular edema. They received an intravitreal injection of 4 mg triamcinolone acetonide. Follow-up was for 1 year with repeat injections where appropriate. Outcome measures we re visual acuity and macular thickness measured using ocular coherence tomography (OCT).

Results:  

Eight eyes responded well with improved visual acuity and macular thickness 1-5 months postinjection. All eight eyes developed recurrent macular edema and six received repeat injections. Two patients declined a second injection. No improvement in visual acuity or OCT macular thickness was seen after the second injection with visual acuity returning to baseline levels at 1-year follow-up. Three eyes showed no response to the initial injection (no improvement in macular thickness or visual acuity). Two patients had a rise in intraocular pressure requiring treatment.

Conclusions:

Intravitreal injection of triamcinolone acetonide is effective as a short-term treatment of macular edema owing to retinal vein occlusion, improving both visual acuity and macular thickness. However, this effectiveness is not maintained after 1 year despite repeat injections.