Concept sparing surgery vitreomacular interface includes – a differentiated minimally invasive approach based on the principles of visualization transparent structures, which allows to selectively remove the membrane staining both without and without vitrectomy and with additional visualization tools, flexibility varying between individualized choice. The study included 18 patients with different pathologies vitreomacular interface. Patients depending on the nature of pathological changes in the macula were divided into 6 groups: the first group consisted of 5 patients with macular hole, the second group – of 3 patients with the first stage of macular hole, the third group – 3 lamellar macular hole, the fourth group – 3 patients with epiretinal fibrosis, the fifth group – 2 patients with optic disc pit complicated by detachment of the neuroepithelium, the sixth group – 2 patients with proliferative diabetic retinopathy and maculopathy. All patients before and after surgery the following studies: visometry, optical coherence tomography (OCT) scanners to «Stratus» and «Cirrus» company «Carl Zeiss Meditec». To implement dynamic intraoperative histological monitoring macular during surgical interventions used surgical microscope with an integrated high-resolution OCT (Carl Zeiss Meditec OPMI LUMERA® 700 with the integrated SD-OCT camera RESCAN 700). In vitreomacular interface, no other membrane except PH (posterior hyaloid) and ILM, which was confirmed by intraoperative dynamic OCT. The fibrous tissue around the fracture is vitreous remnants of PH. The ring of fibrous tissue around the fracture unrelated to ILM. Deleting ILM through macular detachment does not break the remnants of PH and damage the neuroepithelium, as some surgeons. Deleting ILM through macular detachment does not break the remnants of PH and damage the neuroepithelium. PH and ILM are not linked to foveola – various anatomical structures. Adhesion PH around break – too strong, remove it from the edges of the hole can only be intentional. ILM is easily visualized in the OCT. ILM tends to curl into a tube, which facilitates its search for OCT. Carrying intraoperative OCT possible in the air. Intraoperative OCT – control is not an alternative to staining. This technology realizes the histological control of completeness remove the unpainted membrane. Integration OCT microscope and gives rise to a new scientific method based on immersion into the action, where the total disclosure of syncretic continuum histology – topographic anatomy of the macular area in real surgical dynamics.

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