To evaluate the prognostic factors and effect of half-fluence photodynamic therapy (PDT) in the treatment of chronic central serous chorioretinopathy (CSC).


We retrospectively reviewed fifty-six eyes of 56 patients with chronic CSC who underwent half-fluence PDT. Postoperative evaluation included improvements in visual acuity, changes in central macular thickness with the optical coherence tomography (OCT), and recurrence.


BCVA (logMAR) was significantly improved from 0.27±0.25 to 0.14±0.20 at 3 months (p<0.001, n=56); 0.12±0.22 at 6 months (p<0.001, n=40); 0.12±0.23 at 12 months (p<0.001, n=33). And the mean CMT (μm) was significantly decreased from 401.39±105.15 to 244.07±48.40 at 3 months (p<0.001, n=56); 239.78±30.77 at 6 months (p<0.001, n=40); 251.15±44.06 at 12 months (p<0.001, n=33). Five patients recurred during follow-up periods and 4 (80%) of them were smokers. The cases with focal leaking in FAG dried better at 3 months OCT.


Half-fluence PDT is an effective treatment option for chronic CSC, resulting in improvement of VA and decrease of CMT at 3 months, which was maintained up to 12 months period.

Contact Details:

Email: changwh@ynu.ac.kr
Cell Phone: +821093560625

Woohyok Chang