Hassan Mortada (Cairo, Egypt)


Full macular translocation (FMT) has the advantages of complete removal of CNVMs not responding to repeated anti-VEGF intravitreal injections, reposition of the macular area over healthy retinal pigment epithelium and choriocapillaris and restoration of the normal macular configuration and function.


The last eye of 7 patients (fellow eye had disciform scar) underwent FMT for treatment of persistently active CNVM in spite of repeated intravitreal injections of anti-VEGF (Lucentis and/or Avastin). The average number of intravitreal injections was 3. All eyes showed no response to anti-VEGF as evidenced by OCT. No operative complications were encountered. All eyes underwent muscle surgery at the time of silicone oil removal.  All eyes remained stable with attached retinas. All patients showed improved vision for distance and reading.

Effectiveness / Safety:

FMT is a mature technique in experienced hands. It is effective in improving both distance and reading vision in the last eye not showing response to anti-VEGF.

Take home message:

When the only seeing eye is affected by neovascular ARMD, with no response to anti-VEGF, one should consider FMT at the proper timing.