Foveal Avascular Zone Distortion in Epiretinal Membrane by Optical Coherence Tomography Angiography



To show the morphologic changes on the foveal avascular zone (FAZ) in epiretinal membrane (ERM) patients using optical coherence tomography angiography (OCTA) and to demonstrate the correlation between the density of the ERM and distortion of FAZ;


FAZ index (longest diameter of FAZ/shortest diameter of FAZ) was measured on the superficial slab of the OCTA images of 30 patients (32 eyes) with ERM and compared to those with healthy eyes. The density of the ERM was quantified using pesudocolor multicolor images.


FAZ index significantly increased in ERM eyes compared to those with healthy retina (1.8±1.2 versus 0.98±0.9, p=0.003) and this index was positively correlated with the density of the membrane. Elongation of FAZ was seen in 25 eyes along the axes where the striae were prominent on pseudocoloar images.


Optical coherence tomography angiography enables visualizing mechanically apparent changes in FAZ architecture due to tractional forces, and this change is correlated with the density of the membrane.


Ilkay Kilic Muftuoglu
San Diego, United States
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