Richard B. Rosen, MD (New York, NY), Patricia Garcia, MD (New York, NY),* Mark Hathaway, PhD (Canterbury, Kent, UK),* Thomas Muldoon, MD (New York, NY), Ronald Gentile, MD (New York, NY), Sean Lalin, MD (New York, NY), Eric Fitz, MD (New York, NY), John Rogers, PhD (Canterbury, Kent, UK),* Justin Pedro, PhD (Toronto, Canada),* Adrian Podoleanu, PhD (Canterbury, UK)*


To describe new aspects of common retinal pathologies revealed by the comparison of spectral OCT and temporal OCT/SLO images obtained in a dual mode high speed ultrahigh resolution OCT/SLO system and compare them to studies from conventional devices.


A custom high speed ultrahigh resolution dual spectral and temporal OCT~SLO imager was built using a broadband superluminescent diode (SLD) light source. The system which produces paired C-scan (coronal) OCT and confocal SLO-type images along with ultrafast B-scan OCT slices was optimized to exploit the best features of both OCT imaging modalities. 30 patients seen at the New York Eye and Ear Infirmary with a variety of common retinal pathologies were studied to compare the differences in appearance of various anatomic features revealed by the opposing modalities within the single system.


Paired spectral and temporal OCT images demonstrated distinct contrasts in appearance of certain anatomic structures while at the same time presenting similar information. The quality of the imaging at the vitreo-retinal interface, internal retinal layers and the outer retina- RPElregion were most variable between the two approaches with advantages noted with each in different cases. While speed of the spectral aspect of the system was most useful for patients with limited fixation, the gestalt of the coronal temporal images appeared most helpful in identifying small focal defects often overlooked even with fast B scan imaging. The higher resolution of the broadband SLD revealed more detail in both modalities but the increased sensitivity often introduced more noise especially in eyes with compromised media.


High speed ultrahigh resolution OCT/SLO imaging with dual spectral and temporal image acquisition was helpful revealing some the quirks of the latest generation of ultrastructure imagers. The ability to switch modalities added additional versatility and improved the overall rate of satisfactory image acquisition in challenging subjects.
* Financial interest disclosed