Purpose:

To compare the diagnostic accuracy and risk factors for metamorphopsia between M-CHARTS and preferential hyperacuity perimeter (PHP) in the patients with resolved central serous chorioretinopathy (CSC).

Methods:

This study included patients with resolved CSC without macular oedema on optical coherence tomography (OCT). We evaluated metamorphopsia using M-CHARTS and PHP. Foveal microstructure was assessed with spectral-domain OCT including central retinal thickness, the presence of pigment epithelial detachment and the integrity of cone outer segment tip line, photoreceptor inner/outer segment junction line and external limiting membrane. We analysed the relationship between metamorphopsia and clinical factors including age, sex, logMAR best-corrected visual acuity (BCVA), chronicity of CSC, type of treatment and foveal microstructures on OCT.

Results:

We included 29 eyes of 28 patients with resolved CSC. M-CHARTS detected metamorphopsia in 18 eyes (62.1%) with mean metamorphopsia score of 0.3±0.1, whereas PHP in 14 eyes (48.3%) with mean total volume of 7048.8±7456.9. The findings of M-CHARTS and PHP were concordant in 13 eyes (44.8%). There was no significant correlation in detection for metamorphopsia between M-CHARTS and PHP (P = 0.454). The eyes with metamorphopsia on M-CHARTS had significantly greater proportion of chronic CSC (18 eyes, 100%) than those without (7 eyes, 63.6%; P = 0.014). The eyes with metamorphopsia on PHP showed significantly older age and worse final BCVA (57.5±10.6 years, 0.2±0.3) rather than those without (48.1±7.2 years, 0.0±0.1; P = 0.009, 0.045, respectively). Other clinical factors were not related with metamorphopsia detected by M-CHARTS or PHP.

Conclusion:

M-CHARTS and PHP did not show correlated diagnostic performance for metamorphopsia in the patients with resolved CSC. It might alert the clinicians to consider that M-CHARTS and PHP are still tentative diagnostic tools to detect metamorphopsia in the patients with resolved CSC.

Contact Details:

Email: vitric79@naver.com
Cell Phone: +821090052699

SoHyun Bae