Determination of Choroidal Thickness in Closed and Persistent Macular Holes


SCIENTIFIC POSTER


ABSTRACT

Purpose:

To compare the choroidal thickness (CT) between persistent and closed macular holes (MHs) following surgery.

Methods:

35 eyes of 35 patients who underwent standart MH surgery (pars plana vitrectomy, internal limiting membrane peeling, 20 % sulphur hexafluoride endotamponade and face down positioning for 1 week) in Mugla Sıtkı Kocman University School of Medicine between in 2015 and 2016 were included. MH dimensions (minimum hole diameter and hole base diameter) and CTs from various points (subfoveal, temporal, nasal, superior and inferior 1500µ from the center of the fovea) were measured with optical coherence tomography (OCT). Patients who were examined between 9 AM-12 PM were included in the study to avoid the effect of diurnal variation on CT measurement. To adjust the potential compounding factors, aged, sex and axial length matched patients were included in this study. Axial lengths (AL) were measured with swept-source optical biometry.

Results:

Mean base diameter (930±317µ vs 1273±320 µ, p=0.005), mean minimum hole diameter 395±151 µ vs 658±185 µ, p<0.001 were significantly lower in closed MHs than persistent MHs. Mean subfoveal CT (236±32µ vs 204±22.2 µ, p=0.006) was also significantly higher in closed MHs than persistent MHs. At various points (temporal, nasal,superior and inferior 1500µ from the centre of the fovea) mean CTs were insignificant between closed and persistent MHs. Difference of AL, age and sex were insignificant between closed and persistent MHs.

Conclusion:

Subfoveal CT seem to be thinner in persistent MHs in addition to minimal hole and hole base diameter. Local subfoveal choroidal thinning might have a negative effect on MH healing process.


CONTACT DETAILS

Aylin Karalezli
Muğla, Turkey
Email : akaralezli@yahoo.com
Cell Phone: +905301140480
Work Phone: +905301140480