Despite numerous studies describing predominantly its clinical course, many aspects of central serous chorioretinopathy (CSCR) remain unclear. Hypotheses on the pathogenesis of CSCR have ranged from a basic alteration in the choroid to an involvement of the retinal pigment epithelium (RPE).


We reviewed the different therapeutic approaches, including adrenergic antagonists, carbonic anhydrase inhibitors, mifepristone, ketoconazole, laser photocoagulation, intravitreal injection of bevacizumab, and photodynamic therapy with verteporfin (PDT).


The goal of this work is to present our philosophy for CSCR. The philosophy of a model of CSCR enables us to understand how the therapeutic approach should be individualized for each patient, and that sometimes a combined strategy of treatment is required.

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Email: itanev@skycode.com
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Ivan Tanev