Advantages:

To report normal choroidal thickness and volume measurement in healthy eyes using swept source optical coherence tomography (SS-OCT). Additionally to correlate the results with axial length, age and refractive error.

Methods:

Prospective observational study of 122 healthy eyes. All patients underwent a complete ophthalmologic examination. Imaging was performed with SS-OCT. Choroidal thickness and volume measurements were displayed as the mean and standard deviation for each of the 9 regions defined in Early Treatment Diabetic Retinopathy Study. Axial length was measured with optical low coherence reflectometry. Additionally age and refractive error were integrated in the statistical analysis.

Effectiveness:

The choroid has focally increased thickness under the fovea (manual measurement, p<0.001). The choroid was thinnest in the outer nasal quadrant. In stepwise regression analysis, age was estimated as the most significant factor correlating with decrease of choroidal thickness (F=23,146, p<0.001), followed by axial length (F=4.902, p=0.03). Refractive error was not statistically significant (F=1.16, p=0.28). Choroidal thickness and volume measurements derived from SS-OCT images have potential value for objectively documenting disease- related choroidal thickness abnormalities and monitoring progressive changes over time.