Barbara Parolini, Grazia Pertile (Verona, Italy)

A 14-year-old boy came to our attention in August 2008 for vision loss in the left eye. Since January 2008, his left eye had progressivery lost vision to 0,1 Snellen BCVA. He presented with a massive submacular exudation due to vascular abnormalities located in the temporal quadrant. A choroido-retinal anastomosis was visible on fluorescein angiography. Magnetic resonance imaging of the brain and main organs was negative for vascular abnormalities and a diagnosis of Coats’ disease was made. Cryotherapy was applied to the peripheral quadrant in september 2008 obtaining a partial reabsorbtion of the subretinal hard exudates with no change in vision. An intravitreal injection of bevacizumab was performed in February 2009 obtaining a quick reabsorbtion of the subretinal exudate and an improvement in vision to 0,5 in two months. We think that intravitreal injection of bevacizumab may help improving the absorption of intraretinal and subretinal fluid in Coats’ Syndrome.