SCIENTIFIC POSTER_Jaehyung Han

Purpose:

To describe characteristics of acute retinal pigment epitheliitis by analyzing 16 cases.

Methods:

Retrospective chart review of patients diagnosed with acute retinal pigment epitheliitis was performed. Medical records, fundus photos, optical coherence tomographic (OCT) and fluorescein angiography findings (FAG) findings were reviewed.

Results:

The average age at diagnosis was 39.6 years with a male to female ratio of 2:1. Acute metamorphopsia or central scotoma with slight decreased vision were major complaints. Symptoms resolved spontaneously after a mean of 60.1 days. Funduscopic findings revealed pigment mottling in the macular area surrounded by yellow hypopigmented areas. Some cases showed some subretinal fluid. Disruption of the photoreceptor inner and outer segment interface (IS/OS line) with hyperreflection at the level of the retinal pigment epithelium (RPE) was found by OCT examination. On FAG, a window defect was seen. Retinal pigment epithelial changes persisted after resolution of symptoms in all cases.

Conclusion:

Acute retinal pigment epithelitiis is an infrequent macular disorder in young adults. They complain of metamophopsia or a central scotoma, retinal imaging with OCT and FAG show RPE alterations, but the outer retina may be affected as well. Differential diagnosis is important beause of the good prognosis without treatment.