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New Lutein-based Dyes vs Standard Synthetic Dyes in Vitreoretinal Interface Surgery

SCIENTIFIC POSTER 2016_New Lutein-based Dyes vs Standard Synthetic Dyes in Vitreoretinal Interface Surgery Purpose: To compare anatomic, functional, microperimetric and electrofunctional outcomes among patients affected by vitreoretinal interface-associated disorders undergoing vitrectomy + epiretinal membrane and/or internal limiting membrane peeling by using new lutein-based dyes or standard synthetic dyes. Materials and Methods: This is...

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Macular ILM-peeling with Lutein Enriched Dye in High Myopic Eyes

ILM-peeling is a PVR-prophylactic procedure in retinal detachment surgery. High myopia is a main risk factor for retinal detachment. ILM-peeling in high myopic eyes is a challenge even for experienced surgeons. This is due to especially strong connections between vitreous, epiretinal membrane and retinal surface. The prolonged time of ILM-peeling in high myopic eyes could increase the phototoxicity. This can result in potentially worse...

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Why Did I Choose ILM Blue?

Before seeing the advantages of the ILM Blue in ERM surgery, compared to the other dyes, we must analyze what we want to dye: ERM is composed on: A plaque of posterior hyaloid which is a collagen 2 structure responsible of reflection and metamorphopsia. The ILM (one micron collagen 4 structure) invaded by glial proliferation (astrocytes and Mueller cell end-feet filled with microfibrils of GFAP). ILM peeling works because, when we remove...

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ERM Negative Staining and Double Peeling with Brilliant Blue G

Introduction: Epiretinal membrane surgery is a demanding, state-of-the-art procedure. Vitreoretinal surgeons continuously seek to perfect their results, maximizing results and reducing complications and toxicity. Based on our belief and experience of the benefits of combined ERM and ILM peeling when removal of the former is indicated, we present our technique that we believe is both effective and safe. Methods: We present our adopted...

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Why Did I Choose Trypan Blue (Membrane Blue / Membrane Blue Dual)?

I use routinely trypan blue since 2002 and operated more than 5000 cases during that time. Trypan blue is a non- specific dye. It stains vitreous, epiretinal membranes and ILM and I find it as an advantage to have improved visualization of all the tissue with a single dye. Trypan blue is non- toxic. Trypan blue is approved for vitreoretinal surgery. The effectiveness of staining depends on the observation system Different cases/ surgical...

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Efficacy and Safety Analysis of Intraocular Lutein-based Dyes for Vitreoretinal Surgery in Preclinical and Clinical Models

SCIENTIFIC POSTER_Mafalda Figueiredo Purpose: To investigate the efficacy and safety of novel dyes composed of lutein in association with brilliant blue for staining the vitreous and the internal limiting membrane (ILM) during vitreoretinal surgery in pre-clinical and clinical human models. Methods: The preclinical efficacy of lutein-based dyes (Retidyne and Retidyne Plus) was tested in sixty human cadaveric eyes undergoing vitreoretinal...

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