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Photoreceptor Change and Visual Outcome After Idiopathic Epiretinal Membrane Removal with or Without Additional Internal Limiting Membrane Peeling

Advantages: To compare postoperative photoreceptor status and visual outcome after epiretinal membrane (ERM) removal with or without additional internal limiting membrane (ILM) peeling Methods: Medical records of forty eyes from 37 patients undergoing ERM removal with residual ILM peeling (additional ILM peeling group) and 69 eyes from 65 patients undergoing ERM removal without additional ILM peeling (no additional peeling group) were...

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Neuroprotective Effects of Sustained-release Intravitreal Fluocinolone Acetonide in RCS Rats

Raymond Iezzi, MD (Detroit, MI), Inna Glybina, MD, PhD (Detroit, MI), Paul Ashton, PhD (Watertown, MA),* Gary W. Abrams, MD (Detroit, MI) PURPOSE: Corticosteroids and estrogens have been shown to exibit neuroprotective effects, mediated via the stabilization of lipid membranes and the inhibition of apoptosis. The purpose of this study was to determine if chronic intravitreal delivery of the synthetic corticosteroid, Fluocinolone Acetonide...

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Subretinal Schwann Cell Injections Preserve Plexiform Synapses and Retinal Function in RCS Rats

Isabel Pinilla, MD (Zaragoza, Spain), Nicolás Cuenca, PhD (Alicante, Spain), Yves Sauvé, PhD (Edmonton, Canada), Gema Martínez-Navarrete, (Alicante, Spain), Emilio Abecia Martinez, MD (Zaragoza, Spain), Raymond D. Lund, PhD (Salt Lake City, UT) PURPOSE: To examine the preventive potential of subretinal injections of neurotrophin producing cells (Schwann cells) on retinal circuitry in the RCS (Royal College of Surgeons) rat model of...

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