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Ranibizumab vs Ranibizumab + Laser vs Bevacizumab in the Treatment of Threshold ROP

Media not available due to technical recording problems. EVRS is very sorry for the inconvenience.   Purpose: The aim of the study is to compare the efficacy of intravitreal ranibizumab injection, intravitreal ranibizumab injection combined with retinal laser ablation, and intravitreal bevacizumab injection in treatment of zone and posterior zone 2 severe threshold retinopathy of prematurity (ROP). Patients and methods: A...

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Pars Plan Lensectomy + Vitrectomy in Stages 4 and 5 ROP

Media not available due to technical recording problems. EVRS is very sorry for the inconvenience.   Advantages: Stages 4 and 5 ROP represent a severe form of ROP resulting in visual blindness. Pars plana lvitrectomy with or without lensectomy may offer a dismal prognosis in fixing the retinal detachment. Methods: A series of 15 consecutive cases of severe tractional retinal detachment and falciform folds presenting as stages 4 (8...

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Eight Years Experience with the Use of Bevacizumab in ROP

Media not available due to technical recording problems. EVRS is very sorry for the inconvenience.   Objectives: To report the ocular outcome in retrospective consecutive case series of Type I ROP (stage 3+) who had intravitreal injection of avastin as treatment for acute ROP. Methods: Retrospective review of 32 premature infants clinical cases (50 eyes) who received 0,03 cc of intravitreal bevacizumab as adjuvant treatment for laser...

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Vascular Findings in Eyes After Intravitreal Injection of Bevacizumab for ROP

Purpose: To report vascular findings in eyes that had primary treatment with intravitreal bevacizumab for acute ROP (type I stage 3+ ROP). Methods: Retrospective review of 22 infants (32 eyes) that had primary treatment with intravitreal bevacizumab for Type I (stage 3+) ROP. Of those, fourteen (22 eyes) had Zone I or Posterior Zone II ROP and 8 (10 eyes) had Zone II ROP. The minimum follow-up is 1,5 years and the maximum is 6,5...

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Pars Plana Lensectomy / Vitrectomy in Stages 4 and 5 ROP

Stage 5 ROP is a severe form of ROP resulting in retinal detachment and visual blindness. Pars plana lensectomy vitrectomy may offer a dismal prognosis in fixing these detachments.

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Efficacy and Safety of Intravitreal Bevacizumab Monotherapy for Threshold Retinopathy of Prematurity

The introduction of Intraocular Anti-VEGFs agents have significantly improved the management of a wide variety of neovscular ocular diseases including retinopathy of prematurity (ROP). In our hands, monotherapy treatment with intravitreal bevacizumab (IVB) is a favourable treatment modality in management of threshold ROP. In eyes with iris rubeosis, rigid pupils and vitreous haze where it is difficult to visualize the fundus and perform...

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Macular Unfolding for Managing Macular Folds in Retinopathy of Prematurity

Ehab N El Rayes (Cairo, Egypt) Advantages: To evaluate the efficacy of surgical managment of these folds by vitrectomy and unfolding. 9 infants with macular folds where included in this study from 2003-2010. These folds were due to regressed R.O.P. Folds were managed by vitrectomy and membrane peeling with dissection and unfolding with tissue distribution. Methods: A prospective study was designed to evaluate the efficacy of the procedure....

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Surgical Treatment of Late Onset Tractional RD of Regressed Retinopathy of Prematury

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Evaluating the ROP Occurrence in Premature Children Born in Usti Nad Labem between 1993 – 2001

Lidmila Procházková, Martina Závorková (Ústí Nad Labem, Czech Republic) Advantages: Authors evaluated the long-term results of screening test for ROP in children born in Ústí Nad Labem between January 1, 1993 and December 31, 2001. Methods: Dispensarization is obligatory in children with birth weight lower than 1500g and with birth coming before the 32nd gestational week. We examined children up to 2000g of weight. This paper...

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Intravitreal Injection of Bevacizumab (Avastin) as an Adjuvant to Peripheral Laser for Treatment of Progressive Threshold Stage 3 Retinopathy of Prematurity

http://www.evrs.eu/medias/2010/congress/Vascular-Pathologies-in-Young-Patients.flv Ahmed El Khashab (Cairo, Egypt) Purpose: To report a retrospective, consecutive, non-comparative case series of progressive threshold stage 3 retinopathy of prematurity (ROP) treated by the conventional peripheral laser therapy together with intravitreal injection of bevacizumab (Avastin). Methods: The study included 25 eyes of 13 patients with progressive...

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Effects of Initial Intravitreal Bevacizumab (Avastin) Prior to Laser Photocoagulation in Threshold Retinopathy of Prematurity

http://www.evrs.eu/medias/2010/congress/Vascular-Pathologies-in-Young-Patients.flv Ihab Saad Othman, Mohamed Sabry, Hany ELMekawy, Hisham Hosny (Giza, Egypt) Advantages: Threshold zone 1 and 2 ROP is a progressive disease with vision threatening complications. In this cohort, we could achieve retinal stabilization when 0.06 mg / 0.05 ml injection was performed 3-4 days prior to retinal ablation. Methods: Fourteen eyes received intravitreal...

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Transscleral Diode Laser Photocoagulation for the Treatment of Threshold Retinopathy of Prematurity: Easier, Faster and Cost-Effective Treatment

http://www.evrs.eu/medias/2010/congress/Vascular-Pathologies-in-Young-Patients.flv Martin Flores-Aguilar, Alicia Flores, Marco Hernandez (Celaya, Mexico) Advantages: Use of transscleral diode laser for ROP present some advantages over transpupillar photocoagulation: bigger spot size (the more retina treated, the less time of treatment). If tunica vasculosa lentis is still present we don’t need to have a very dilated pupil, the probe...

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Treatment of Aggressive Posterior ROP

Authors: Susana Teixeira, Manuela Bernardo, Graça Pires, Filomena Silva, Diogo Cavalheiro, Rosalina Barroso, Lisbon, Portugal Advantages: Aggressive Posterior ROP (AP-ROP) is a unique presentation of ROP that, even with the best standard treatment (pre-threshold laser ablation of anterior avascular retina) leads to unfavorable anatomic (55,2%) and functional (58%) results. As the proliferative phase (ROP Phase II) is associated with high...

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Intravitreal Bevacizumab in Retinopathy of Prematurity: 30 Months Follow-Up. Will we Change our Way of Treating ROP?

http://www.evrs.eu/medias/2008/congress/Intravitreal-Bevacizumab-in-Retinopathy-of-Prematurity:-30-Months-Follow-Up.-Will-we-Change-our-Way-of-Treating-ROP.flv Maria Ana Martinez-Castellanos, Jose Luis Guerrero-Naranjo, J. Gerardo Garcia-Aguirre, Virgilio Morales-Canton, Omar Honerlage-Merino, R.V. Paul Chan, Hugo Quiroz-Mercado Advantages: We present a treatment with antiangiogenic therapy for retinopathy of prematurity with good outcome...

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Intravitreal Anti-Vascular-Endothelial-Growth-Factors (Anti-VEGFs) for Severe Retinopathy of Prematurity

http://www.evrs.eu/medias/2008/congress/Intravitreal-Anti-Vascular-Endothelial-Growth-Factors-(Anti-VEGFs)-for-Severe-Retinopathy-of-Prematurity.flv Alay S. Banker, Ajay Dudani, Rohan Chauhan, Urvashi Goja Advantages: Evaluate efficacy of intravitreal Anti-VEGF agents in severe retinopathy of prematurity (ROP) alone or with laser. Methods: Prospective study of 34 eyes with severe ROP treated with intravitreal Anti-VEGFs (28-Bevacizumab,...

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The Role of Anti Vascular Endothelial Growth Factor (VEGF) Therapy (Bevacizumab) in the Management of Retinopathy of Prematurity

http://www.evrs.eu/medias/2008/congress/The-Role-of-Anti-Vascular-Endothelial-Growth-Factor-(VEGF)-Therapy-(Bevacizumab)-in-the-Management-of-Retinopathy-of-Prematurity.flv Ehab N El Rayes Advantages: To evaluate the possible role of using Anti VEGF therapy (Bevacizumab ) in treating retinopathy of prematurity (ROP). Methods: 38 eyes of infants with ROP received Anti VEGF (Bevacizumab) 1.25 mg / 0.05 ml for varying stages of ROP. Group 1...

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Diode Laser Treatment of Retinopathy of Prematurity – Anatomical and Refractive Outcomes

Ruth Axer Siegel (Petah Tikva, Israel), Idit Maharshak, MD (Petah Tikva, Israel), Rita Ehrlich, MD (Petah Tikva, Israel), Ronit Friling, MD (Petah Tikva, Israel), Dov Weinberger, MD (Petach Tikva, Israel), Lea Sirota, MD (Petah Tikva, Israel), Benjamin Shalev, MD (Petah Tikva, Israel), Ilana Sherf, Bsc (Petah Tikva, Israel), Moshe Snir, MD (Petah Tikva, Israel) PURPOSE: To report the anatomical and refractive outcomes of infrared diode...

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Neonatologists and the Management of Retinopathy of Prematurity (ROP)

Kristen L. Hartley (Miami, FL), Audina M. Berrocal, MD, FACS (Miami, FL), Amy C. Schefler, MD (Miami, FL), Magaly Diaz-Barbosa, (Miami, FL) PURPOSE: To attempt to understand where the need for more teaching should be directed. METHODS: A multiple-choice on-line questionnaire was sent to all 4,136 Board-certified neonatologists in the United States to determine their depth of knowledge regarding retinopathy of prematurity. RESULTS: Will be...

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Retinopathy of Prematurity (ROP) Screening Guidelines Using Birthweight (BW) of Less Than or Equal to 1250 Grams as Sole Inclusion Criteria

Shailesh Gupta, MD (Jacksonville, FL), K.V. Chalam, MD, PhD (Jacksonville, FL), Swati Agarwal, MD (Jacksonville, FL), Sandeep Chalam, (Jacksonville, FL), Sandeep Grover, MD (Jacksonville, FL) PURPOSE: To determine if BW alone can predict the need for inclusion in ROP screening guidelines. METHODS: Design: An unmasked retrospective chart review. Participants: 526 infants screened for ROP using AAPOS guidelines. Methods: Variables examined...

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Surgical Results in Advanced Stages of ROP

Georges Caputo, MD (Paris, France), Florence Metge, MD (Paris, France), Nicolas Teyssot, MD (Paris, France), Pascale Dureau, MD (Paris, France), Catherine Edelson, MD (Paris, France) PURPOSE: The aim of this study is to evaluate anatomical and functional outcome of vitrectomy in eyes presenting with retinal detachment secondary to stage 4B or 5 retinopathy of prematurity. METHODS: Retrospective study of all ROP patients treated with...

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Anti-VEGF Therapy for Pediatric Retinopathies: Which Case Is the Right Case?

http://www.evrs.eu/medias/2006/congress/Anti-VEGF-Therapy-for-Pediatric-Retinopathies:-Which-Case-Is-the-Right-Case.swf Kimberly A. Drenser, MD (Royal Oak, CA), Michael T. Trese, MD (Royal Oak, MI), Antonio Capone, MD (Royal Oak, MI) PURPOSE: To review the usefulness and the appropriate case selection of anti-VEGF agents for the treatment of vitreoretinopathies in the pediatric population. METHODS: Patients with either retinopathy of...

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Safety and Efficacy of Intravitreal Bevacizumab for Retinopathy of Prematurity

http://www.evrs.eu/medias/2006/congress/Safety-and-Efficacy-of-Intravitreal-Bevacizumab-for-Retinopathy-of-Prematurity.swf http://www.evrs.eu/medias/2006/congress/Safety-and-Efficacy-of-Intravitreal-Bevacizumab-for-Retinopathy-of-Prematurity.flv Hugo Quiroz-Mercado, MD (Mexico City, Mexico), ACV Travassos, MD (Lisboa, Portugal), Maria Ana Martinez-Castellanos, MD (Mexico City, Mexico, Mexico), Griselda Alvarez-Rivera, MD (Mexico City,...

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Telemedicine Screening for Retinopathy of Prematurity: The Stanford Experience (SUNDROP)

http://www.evrs.eu/medias/2006/congress/Telemedicine-Screening-for-Retinopathy-of-Prematurity:-The-Stanford-Experience-(SUNDROP).swf Steven Sanislo, MD (Menlo Park, CA), Darius M. Moshfeghi, MD (Menlo Park, CA) PURPOSE: To describe the Stanford University Network for Diagnosis of Retinopathy of Prematurity (SUNDROP) telemedicine screening initiative. METHODS: Three neonatal intensive care units (NICUs) affiliated with Lucile Packard...

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Vitreoretinal Surgery in Stage 5 ROP

http://www.evrs.eu/medias/2006/videos/Vitreoretinal-Surgery-in-Stage-5-ROP.flv Sven Crafoord, MD, PhD (Orebro, Sweden) SYNOPSIS Progression of Retinopathy of Prematurity (ROP) despite screening and laser treatment still occurs in some children. Once the ROP presents itself in an infant with bilateral stage 5 the vitreoretinal surgeon faces a demanding task. Some cases are candidates for a surgical effort to open up the total traction...

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