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Dexamethasone Implant in a Pregnant Woman for the Treatment of ME in CRVO

Poster Jesus Zarallo Gallardo Introduction: There are several retinal diseases that may worsen or alter during pregnancy as a result of hematologic, hormonal, metabolic, cardiovascular, and immunologic changes. Although normal pregnancy and its hypercoagulable state may induce retinal vein occlusion, hereditary or acquired changes in hemostatic factors increase the risk of thromboembolic events. The risk of venous thromboembolism in...

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Surgery Associated with Intravitreal Anti-VEGF Agents in CRVO. A More Rational Approach?

http://www.dailymotion.com/video/xukzpn http://www.dailymotion.com/video/xuk625 Central retinal vein occlusion is a multi-factorial event. Like any venous thrombosis, one of the key components in play is stenosis of the vessel. In the eye, this stenosis generally originates from the vein being compressed by a sclerotic artery in a non-expandable space such as the optic nerve at the level of lamina cribrosa. Resection of the lamina cribrosa...

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3 Bevacizumab vs 2 Triamcinolone Injections in Recent CRVO

http://www.dailymotion.com/video/xukzpn http://www.dailymotion.com/video/xuk625 Advantages: Repeated intravitreal injections of bevacizumab (IVB) are more efficacious than repeated intravitreal injections of triamcinolone (IVT) in the treatment of macular edema in eyes with acute central retinal vein occlusion (CRVO). Methods: In a randomized clinical trial, 110 eyes with recent onset (less than 12 weeks) CRVO were included. Participants...

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Ischemic Changes After Intravitreal Injections for Treatment of ME with CRVO

Advantages: To investigate the ischemic changes after intravitreal injection for treatment of ME with CRVO. Methods:   55 patients treated with anti-VEGF for ME with CRVO were included. Take home message: Intravitreal injection for ME with CRVO could induce ischemic changes in some cases. So these possibilities have to be notified to patients and close follow-up is...

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Early Treatment of ME Secondary to CRVO with Intravitreal Bevacizumab

Advantages: To evaluate visual and anatomical outcomes of macular edema (ME) secondary to central retinal vein occlusion (CRVO) after early onset treatment with intravitreal injections of bevacizumab (IVB). Methods: Ten consecutive eyes with ME secondary to nonischemic CRVO were included in this retrospective study. All patients had fundus fluorescein angiography (FFA) and optical coherence tomography at presentation. All patients were...

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Treatment of Macular Edema Secondary to Central Retinal Vein Occlusion: Comparison of Pars Plana Vitrectomy with Internal Limiting Membrane Peeling and Intravitreal Bevacizumab Injection

Hande Etus, Levent Karabas, Yusuf Çaglar (Kocaeli, Turkey) Advantages: To compare anatomic and functional results in patients with macular edema in central retinal vein occlusion (CRVO) treated with pars plana vitrectomy (PPV) with internal limiting membrane (ILM) peeling and intravitreal bevacizumab injection treatment (IVBT). Methods: A total of 29 patients were examined retrospective. PPV with ILM peeling was performed in Group A...

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Why Use the Pascal Laser to Treat Retinal Vascular Ischemic Pathologies and Macular Edemas?

http://www.evrs.eu/medias/2010/congress/Branch-Retinal-Vein-Occlusion-Central-Retinal-Vein-Occlusion.flv Catherine Favard (Paris, France) Advantages: The Pattern Scanning Laser (Pascal) is a semi-automatic photocoagulator using short pulses of 10 to 20 milliseconds applied in square (2X2 to 5X5 impacts) or grid (14 to 56 impacts) patterns. Methods: Between March 2008 and May 2010, 27 eyes: 15 Ischemic diabetic retinopathies (DR) and 12...

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Radial Optic Neurotomy Revisited

http://www.evrs.eu/medias/2010/congress/Branch-Retinal-Vein-Occlusion-Central-Retinal-Vein-Occlusion.flv Giampaolo Gini, Giorgio La Rocca (Florence, Italy) Advantages: RON offers dramatically better anatomic and functional results as compared to non-surgical procedures provided that the following criteria are used: – proper patient selection – early intervention – ILM peeling. Methods: Early vitrectomy associated with...

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Combined Treatment of CME after Branch Retinal Vein Occlusion

http://www.evrs.eu/medias/2010/congress/Branch-Retinal-Vein-Occlusion-Central-Retinal-Vein-Occlusion.flv Ivan Fiser, Martina Rubesova (Prague, Czech Republic) Advantages: In most cases of persisting CME after BRVO we use vitrectomy with ILM peeling which has a good effect in more than 60 % of eyes but. In some patients we start with Avastin that brings a repeated benefit but later recurrences of CME happen. Laser coagulation in edematous...

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Combined Treatment of CME after Central Retinal Vein Occlusion

Ivan Fiser, Martina Rubesova (Prague, Czech Republic) Advantages: CME after CRVO is a typical case where it is very difficult to define which treatment is best to start with. Triamcinolone can be helpful (which was shown in a recent study) but a recurrence can happen. Avastin also has a temporary effect. ILM peeling can be beneficial, too, but we also see recurrences of CME after it. Laser treatment of edematous retina is difficult. We...

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Central Retinal Vein Occlusion / Branch Retinal Vein Occlusion: It is More Brilliant to Peel the ILM

http://www.evrs.eu/medias/2010/congress/Branch-Retinal-Vein-Occlusion-Central-Retinal-Vein-Occlusion.flv Didier Ducournau (Nantes, France) Last year, during the 2009 EVRS congress, we presented the results of ILM removal on 236 patients presented a macular edema after BRVO (82) and CRVO 154); more than one year after operation, the obtained improvement (in LorMAR lines) was superior to 5 lines i.e. twice as much than after repeated...

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ILM Peeling in Branch Retinal Vein Occlusion & Central Retinal Vein Occlusion

http://www.evrs.eu/medias/2010/congress/Branch-Retinal-Vein-Occlusion-Central-Retinal-Vein-Occlusion.flv Jean-Paul Amar (Cannes, France) The author made a study on 130 cases over 3 years. The results confirmed those presented last year by Didier Ducournau. The removal of the ILM demonstrates a long-term improvement of visual acuity and a nearly total disappearance of neovascular glaucoma. The importance of the improvement is higher than the...

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Avastin Laser Combination Equivalent to ILM Peeling in Central Retinal Vein Occlusion: A Review of Cases

http://www.evrs.eu/medias/2010/congress/Branch-Retinal-Vein-Occlusion-Central-Retinal-Vein-Occlusion.flv Theodoros Potamitis, Yianna Antoniou (Limassol, Cyprus) Advantages: The use of Avastin has revolutionized the management of many retinal vasculopathies over the past few years and when its use leads to the avoidance of surgery the advantages to the patient are obvious. Methods: Patients over a five-year period with CRVO treated by both...

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Three-Intravitreal Bevacizumab vs Two-Intravitreal Triamcinolone Injections in Retinal Vein Occlusion

http://www.evrs.eu/medias/2010/congress/Branch-Retinal-Vein-Occlusion-Central-Retinal-Vein-Occlusion.flv Alireza Ramezani, Morteza Entezari, Siamak Moradian, Hamed Esfandiari, Babak Dehsarvi, Masoud Soheilian, Hamid Ahmadieh, Mehdi Yaseri (Tehran, Iran) Advantages: Repeated intravitreal injections of bevacizumab (IVB) are more effective than repeated intravitreal injections of triamcinolone (IVT) in acute retinal vein occlusion...

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Retrospective Analysis of 16 Patients with Central Retinal Vein Obstruction

Hülya Güngel, Ozen Osmanbasoglu, Ebru Demet Aygit (Istanbul, Turkey) Advantages: To evaluate the clinical findings and treatment outcomes in patients with central retinal vein obstruction (CRVO). Methods: 16 patients’ data that were followed more than 6 months were evaluated. Based on the angiographic findings patients were grouped as ischemic and non-ischemic CRVO. Visual acuity, OCT findings and treatment modalities were...

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Intravitreal Injection of Bevacizumab for the Treatment of Macular Edema Secondary to Retinal Vein Occlusion

http://www.evrs.eu/medias/2010/congress/Branch-Retinal-Vein-Occlusion-Central-Retinal-Vein-Occlusion.flv Salim Ben Yahia, Riadh Messaoud, Imen Chtioui, Rim Kahloun, Sonia Zaouali, Moncef Khairallah (Monastir, Tunisia) Advantages: To manage macular edema secondary to retinal vein occlusion with intravitreal injection of bevacizumab. Methods: Thirty eyes of 30 patients with macular edema secondary to retinal vein occlusion (central retinal...

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Examination of the Relation Between Clinic, Fluorescein Angiographic Findings and Ophthalmodynamometric Measurements in Patients with Central Retinal Vein Obstruction

http://www.evrs.eu/medias/2010/congress/Branch-Retinal-Vein-Occlusion-Central-Retinal-Vein-Occlusion.flv Hülya Güngel (Istanbul, Turkey) Advantages: To examine the relation between clinic, fluorescein angiographic findings and ophthalmodynamometric measurements in patients with central retinal vein obstruction. Methods: Routine ophthalmologic examination, fluorescein angiography and ophthalmodynometry was performed in 28 subjects. H.K....

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Intravitreal Growth Factors in Central Retinal Vein Occlusion and Branch Retinal Vein Occlusion

http://www.evrs.eu/medias/2010/congress/Branch-Retinal-Vein-Occlusion-Central-Retinal-Vein-Occlusion.flv Michael Koss, M. Pfister, F. Rothweiler, M.  Michaelis, J.  Cinati, Pankaj Singh, Frank Koch (Frankfurt am Main, Germany) Advantages: To determine the levels of intravitreal VEGF A, monocytic adhesion protein = MCP, and IL-6 levels in retinal vein obstruction over a clinical observation time. Methods: Twelve patients with central...

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Central Retinal Vein Occlusion – Anticoagulant Treatment with Warfarin

Jiri Rehak, (Olomouc, Czech Republic), Evzen Fric, MD (Olomouc, Czech Republic), Matus Rehak, MD (Olomouc, Czech Republic), Barbora Babkova, MD (Olomouc, Czech Republic), Zuzana Pracharova, MD (Olomouc, Czech Republic) PURPOSE: It is generally thought that don’t exist effective treatment of central retinal vein occlusion (CRVO). This study evaluate the effect of anticoagulant treatment with warfarin on visual acuity (VA) in the therapy of...

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Intravitreal Triamcinolone for Acute Central Retinal Vein Occlusion: A Randomized Clinical Trial

Alireza Ramezani, MD (Tehran, Iran), S. Morteza Entezari (Tehran, Iran), Siamak Moradian, MD (Tehran, Iran), Homa Tabatabaei, MD (Tehran, Iran), Shohreh Kadkhodaei, MD (Tehran, Iran) PURPOSE: Central retinal vein occlusion (CRVO) is the most common vascular event in the eye after diabetic retinopathy. This study was conducted to evaluate the therapeutic effect and safety of intravitreal triamcinolone acetonide (IVT) in acute...

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Intravitreal Bevacizumab for Idiopathic Central Retinal Vein Occlusion in a 12 Year Old Girl

Jared S. Nielsen, MD (Chicago, IL), Manjot Gill, MD (Chicago, IL) PURPOSE: To describe an unusual case of idiopathic central retinal vein occlusion (CRVO) in a 12 year old girl, and report successful treatment with intravitreal bevacizumab in this pediatric patient. METHODS: Retrospective report of a single case. RESULTS: A healthy 12 year-old white female presented 3 weeks after painless loss of vision in her right eye (Va: CF2FT)....

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Ophthalmic Arterial Fibrinolysis with Urokinase for Recent Severe Central Retinal Venous Occlusion: Initial Experience

Jose Luis Rosales Meneses, MD, PhD (San Cristobal, Venezuela), Jose G. Rosales Meneses, MD (San Cristobal, Venezuela) PURPOSE: To investigate the effects of local ophthalmic arterial fibrinolysis on central retinal venous occlusion (CRVO). METHODS: Ten patients had recent severe nonischemic CRVO for which no alternative therapy was available. A flow-guide microcatheter was introduced coaxially via the femoral artery into the ophthalmic...

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Direct Tissue Plasminogen Activator Infusion Into a Branch Retinal Vein in Patients with Central Retinal Vein Occlusion

Sun-Taek Lim, (Gwangju, South Korea), Young-Duk Kim, MD, PhD (Gwangju, Korea), Chang-Ryong Kim, MD, PhD (Gwangju, Korea), Yeon Lee, MD, PhD (Gwangju, Korea) PURPOSE: To evaluate visual acuity outcomes and retinal blood circulation after direct tissue plasminogen activator (t-PA) infusion into a branch retinal vein. METHODS: In this prospective, non-comparative, casecontrol study, ten eyes of ten consecutive patients with central retinal...

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Unilateral Nonischemic Central Retinal Vein Occlusion in Young Adults

Christos D. Kalogeropoulos, MD (Ioannina, Greece), Maria Stefaniotou (Ioannina, Greece), Ioannis C. Asproudis, MD (Ioannina, Greece), Miltiadis B. Aspiotis, MD (Ioannina, Greece) PURPOSE: Central retinal vein occlusion (CRVO) is relatively rare in young adults. Diagnostic approach was performed in a series of patients with unilateral nonischemic CRVO. The disease outcome was correlated to the final diagnosis and therapy. METHODS: Thirty...

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Transvitreal Radial Optic Neurotomy

Hans Hoerauf, MD (Luebeck, Germany), Philipp Steven, MD (Luebeck, Germany) PURPOSE: The role of radial optic neurotomy (RON) as a new treatment option for central retinal vein occlusion (CRVO) is discussed controversially. To rule out a therapeutic effect of vitrectomy, posterior vitreous detachment (PVD) and/or ILM-delamination a transvitreal RON only was performed in 5 patients. METHODS: In 5 eyes of 5 patients with CRVO (2 ischemic, 3...

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Ranibizumab (Lucentis) in Ischemic Central Retinal Vein Occlusion: Interim OCT and Visual Results from the RAVE Trial

Matthew S. Benz, MD (Houston, TX),* David M. Brown, MD (Houston, TX),* Richard H. Fish, MD (Houston, TX),* Rosa Y. Kim, MD (Houston, TX),* Andrew Strickler, MS (Houston, TX), Tien P. Wong, MD (Houston, TX)* PURPOSE: Patients with ischemic central retinal vein occlusion have a high rate of developing anterior segment neovascularization and neovascular glaucoma and often have a dismal visual outcome. The RAVE (Rubeosis Anti-VEGF) study is an...

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Pars Plana Vitrectomy on 23-Year Old Man with Central Retinal Vein Occlusion

Dagmar Dotrelova, MD, PhD (Prague, Czech Republic), Tereza Lainova Vrabcova, MD (Prague, Czech Republic), Jan Kvasnicka, MD (Prague, Czech Republic), Martin Hlozanek, MD (Prague, Czech Republic) PURPOSE: Case report showing complex diagnostics and therapy in young man with central retinal vein occlusion (CRVO). METHODS: CRVO is typically found in population over 60, vascular and hematological disorders are another risk factors. Retinal...

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Intravitreal Bevacizumab for Treatment of Macular Edema in Central and Branch Retinal Vein Occlusion

Ajay Dudani, MD (Mumbai, India), Alay S Banker, MD (Ahmedabad, Gujarat, India), J. Fernando Arevalo, MD, FACS (Caracas, Venezuela) PURPOSE: To report the anatomic and visual acuity response after intravitreal injection of bevacizumab in patients with macular edema due to central retinal vein occlusion (CRVO) and branch retinal vein occlusion (BRVO). METHODS: Prospective study of patients with macular edema due to CRVO/BRVO who were treated...

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New Technique for Acute Central Retinal Vein Occlusion Surgery

http://www.evrs.eu/medias/2006/videos/New-Technique-for-Acute-Central-Retinal-Vein-Occlusion-Surgery.flv Georgiy E. Stolyarenko, MD, PhD (Moscow, Russia) SYNOPSIS New surgical technique of indirect massage of central retinal vein thrombus after acute (4 days) occlusion is shown. Two types of massage – hydrodynamic and mechanical are applied. Two simptomas of passable and unpassable vein are revealed.

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Short Term Visual and Anatomic Outcomes Following Intravitreal Bevacizumab for Macular Edema Secondary to Central Retinal Vein Occlusion

Jose A. Roca, MD (Lima, Peru), Lihteh Wu, MD (San Jose, Costa Rica), Fernando Arevalo, MD (Caracas, Venezuela), Mauricio Maia, MD (São Paulo, Brazil), Maria H. Berrocal, MD (Santurce, PR), Francisco J. Rodriguez, MD (Bogota, Colombia), Michel Eid Farah, MD, PhD (São Paulo, Brazil), Fabio Bom Aggio, MD (São Paulo, Brazil) PURPOSE: To describe the visual and anatomic outcomes of an intravitreal injection of 1.25 mg or 2.5 mg of bevacizumab...

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Particular Profile for Idiopathic Central Retinal Vein Occlusion in Young Adults

Frank J. Becquet, MD, PhD (Nantes, France), Jean-François Le Rouic, MD (Nantes, France), Didier Ducournau, MD (Nantes, France) PURPOSE: To describe and evaluate the prevalence of intensive sport practising among patients with earlyonset central retinal vein occlusion (CRVO). METHODS: Intensive sport practising was evaluated in a consecutive series of 10 patients with CRVO who were younger than 45 years of age (mean age, 37.2 years) from a...

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Pegaptanib Sodium for the Treatment of Macular Edema Following Central Retinal Vein Occlusion

John A. Wells, MD, FACS (Columbia, SC),* PURPOSE: Vascular endothelial growth factor (VEGF) both promotes angiogenesis and enhances vascular permeability. VEGF levels rise following retinal vein occlusion. Selective VEGF blockade has been effective in treating diabetic macular edema. The current trial examined whether this approach was effective in treating macular edema that follows CRVO. METHODS: A randomized, multicenter, double-masked,...

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Radial Optic Neurotomy Plus Intravitreal Triamcinolone with and without Internal Limiting Membrane Peeling for Central Retinal Vein Occlusion

Jose Garcia-Arumi, MD (Barcelona, Spain), Miguel Angel Zapata, MD (Barcelona, Spain), Anna Boixadera, MD (Barcelona, Spain), Alejandro Fonollosa, MD (Barcelona, Spain), Jorge Prieto, MD (Barcelona, Spain), Vicente Martinez-Castillo, MD (Barcelona, Spain) PURPOSE: RON has been proposed to relieve the pressure exerted by scleral ring in CRVO. Vitrectomy, intravitreal triamcinolone and ILM peeling seem to be effective for treating macular...

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Reversal of Ischemic Central Retinal Vein Occlusion: A Novel Technique of Multiple Retinal Vein Decompression and Chorioretinal Venous Anastomosis

Calvin A. Grant, MD (Oak Lawn, IL) PURPOSE: To address the possibility of safe and reproducible multiple sequential branch retinal vein decompression and chorioretinal venous anastomosis for the reversal ischemia central vein occlusion as evidenced by patient satisfaction, vision, pupillary function, and fluorescein and/or ICG angiography. To monitor for neovascularization and vitreous hemorrhage known in laser only CRVA...

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Optical Coherence Tomography Evaluation of Macular Edema after Radial Optic Neurotomy in Patients Affected by Central Retinal Vein Occlusion

http://www.evrs.eu/medias/2005/congress/Optical-Coherence-Tomography-Evaluation-of-Macular-Edema-after-Radial-Optic-Neurotomy-in-Patients-Affected-by-Central-Retinal-Vein-Occlusion.swf F. Patelli, P. Radice, G. Zumbo, F. M. Di Tizio, G. Fasolino, S. Marchi Purpose: To evaluate the characteristics of macular edema (ME) before and after radial optic neurotomy (RON) detected by optical coherence tomography (OCT), in patients with central...

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