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Efficacy and Safety of Subthreshold Laser in Refractory DME Demostrated by Swept Source OCT and Microperimetry

SCIENTIFIC POSTER 2016_Efficacy and Safety of Subthreshold Laser in Refractory DME Demostrated by Swept Source OCT and Microperimetry Patricia Udaondo Purpose: To demostrate de efficacy and safety of subthreshold laser therapy in the management of refractory diabetic macular edema cases. Methods: Patients with persistent macular edema despite several intravitreal injections with antiVEGF and/or steroids were treated with the new streamline...

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Alternative Diffuse DME Treatment: Laser Photostimulation versus Topical Medical Therapy

Introduction: The standard first-line treatment for diffuse diabetic macular edema (DDME) is intravitreal injections. Although considered safer and more effective than laser, these drugs may have serious ocular and systemic complications. Recent research of the pharmacological properties of Nepafenac, found that this drug could reach the retina in sufficient concentrations to produce beneficial effects. We evaluated the efficacy of...

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The Impact of Macular and Peripheral Ischemia in DME

Purpose: To describe the effect of macular and peripheral retinal ischemia in diabetic macular edema (DME). Methods: This is a retrospective study on 259 eyes of 187 patients with DME. Degree of macular ischemia and peripheral retinal ischemia were graded in FFA for each case and macular edema with central foveal thickness (CFT) and structural changes of retinal layers were assessed using OCT. Results: There was macular ischemia of...

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Micropulse Contiguous Grid Laser for Diffuse DME

Objective: To investigate micropulse contiguous grid laser in fovea involved DDME and to correlate SD-OCT structural changes with resolution target visual fields. Purpose: To investigate micropulse contiguous grid laser in the treatment of eyes with DDME involving the fovea, and second, to correlate OCT findings with resolution target visual field (RTVF) measurements of threshold acuity at fixation, best acuity measured at any...

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Safety and Efficacy of Intravitreal Preservative-free Triamcinolone for ME Secondary to Diabetes or Retinal Vein Occlusion

Purpose: To evaluate the efficacy and safety of preservative-free triamcinolone acetonide injectable suspension (Taioftal) for the treatment of macular edema secondary to diabetes or retinal vein occlusion. Design, Setting & Participants: From January 2015 to December 2015, at Ospedale Maggiore of Bologna, a retrospective study was conducted on patients suffering from macular edema secondary to diabetes or retinal vein occlusion....

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Approach to Diabetic Epimacular Membranes in DME Surgery

Approach to Diabetic Epimacular membranes in Diabetic macular Edema surgery Risk of Diabetic Epimacular membranes (ERM) Peeling: These membranes are rather toughly adherent to an underlying fragile ischemic macula. Vascular connections may be present, in or around, the area of the membranes. This may elicit: iatrogenic retinal breaks, uncontrolled retinal bleeding. My Technique: I use Chandelier as the illumination tool, and an aspheric...

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Central Retinal Vein Occlusion: What`s New ?

Despite numerous studies describing predominantly its clinical course, many aspects of central retinal vein occlusion (CRVO) remain unclear. Hypotheses on the pathogenesis of CSCR have ranged from a basic alteration in the blood stream to an involvement of the blood vessel wall. We reviewed the different therapeutic approaches, including laser induced chorioretinal anastomosis (LICRA), vitrectomy (PPV) and intravitreal treatment (IVT)....

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Vitreo-retinal Interface in Non-tractional DME

Vitrectomy is a well-known technique for dealing with “tractional DME”. Most doctors however prefer medical treatment for “non-tractional” DME. Recently performed, ME EVRS study proved that vitrectomy may be a valuable treatment option for “non-tractional” DME. The aim of this presentation is to show the vitreo-retinal relationship in “nontractional DME” revealed during the surgery, pointing that in...

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Role of Endo-diathermy Probe in PDR Surgery

I use the endodiathermy probe as one of two instruments for bimanual dissection of diabetic fibrovascular proliferations. It replaces either the forceps or the vitreous cutting probe and scissors. Forceps Replacement: I identify the surgical planes, by inserting the endodiathermy probe tip underneath the membranes; this allows me to dissect with the vitreous cutting probe under good visulaization. Probe/scissors Replacement: In the...

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Retinal Teleangectasia

              Color and autofluorescence of retinal teleangectasia in a 30 yo boy, partially treated with laser. Contact Details: Email: parolinibarbara@gmail.com Cell Phone:...

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Macular Hole in RD PDR

          Giant macular hole in a 13 yo girl after surgery for retinal detachment. Subretinal strands are also visible. Tamponade is silicone oil. Contact Details: Email: parolinibarbara@gmail.com Cell Phone:...

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Coats Disease: Management of Lipid Exudates by Trans-scleral Drainage, Triamcinolone Injection Followed by Laser Peripheral Ablation

Aim: To evaluate the role of intravitreal Triamcinolone (TA) with or without trans-scleral drainage in management of Coats disease. Methods: Retrospective, interventional case series. Results: Fifteen consecutive cases with Coats disease were managed with 4mg/0.1ml intravitreal Triamcinolone injection on presentation and were followed for a minimum of one year duration. Additional management strategies including drainage of subretinal fluid...

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Chronic Diffuse DME: The Role of Vitrectomy vs Intravitreal Therapy

Introduction: Macular edema is the main cause of visual loss in diabetic patients. In spite of the ample choice of therapeutic modalities, chronic macular edema management is a challenge to this date. Aside from laser and intravitreal therapies, the newest proposal by some authors has been vitrectomy with ILM peeling as a possible solution for many therapy-resistant cases, or even naive cases. Reducing traction, increasing retinal...

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Qualitative and Quantitative Analysis of Retinal Vascular Impairment in Diabetic Maculopathy: An OCT-Angiography Assessment

Purpose: To perform a qualitative and quantitative assessment of the foveal microvasculature in eyes with diabetic maculopathy (DM) using optical coherence tomography angiography (OCT-A). Methods: Retrospective case series of 50 eyes of 34patients with DM (14 females, mean age 64.4 ± 9.2 years) and 30 eyes of 30 age-matched controls, evaluated by conventional multimodal imaging andSpectralis OCT-A (Heidelberg Engineering, Heidelberg,...

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Safety and Efficacy of Intravitreal Ocriplasmin in DME with Vitreomacular Adhesion

Introduction: There are many reports supporting that the relationship of the posterior cortical vitreous to the macula plays a role in the development of diabetic macular edema (DME). Until recently, the only treatment option available for vitreomacular adhesion (VMA) was vitrectomy. Given the risks for vitrectomy, the standard of care has generally been to wait until visual symptoms from VMT have deteriorated enough to justify the...

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Subthreshold Diode Micropulse Laser for the Treatment of Clinically Significant DME Less than 400 μ

Purpose: To assess effect of micropulse diode laser (MPDL) on best corrected visual acuity (BCVA) and central foveal thickness (CFT) in treatment of clinically significant diabetic macular oedema (CSME) as compared to conventional argon green laser (CGL) treatment. Design: Single-center, prospective, interventional, comparative study. Methods: Twenty four patients (40 eyes) with diabetic CSME were randomly assigned to MPDL (n=20) or CGL...

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Micropulse Contiguous Grid Laser for Diffuse DME

Objective: To investigate micropulse contiguous grid laser in fovea involved DDME and to correlate SD-OCT structural changes with resolution target visual fields. Purpose: To investigate micropulse contiguous grid laser in the treatment of eyes with DDME involving the fovea, and second, to correlate OCT findings with resolution target visual field (RTVF) measurements of threshold acuity at fixation, best acuity measured at any intercept...

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Definition of Cystoid Macular Degeneration in DME

Purpose: To describe cystoid macular degeneration (CMD) which had no clear definition in diabetic macular edema (DME) and to investigate related characteristics. Method: Retrospective study. Two hundred fifty one eyes of 179 patients who had cystic changes in OCT were enrolled. The horizontal and vertical diameters of the biggest cyst in the area of 1000µm from the center of the fovea were measured for the definition of CMD. The analysis...

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Microstructural Changes Depicted by OCT in DME: Insight into Pathomorphology and Tailored Management

The introduction of OCT and intravitreal pharmacotherapy has revolutionized the management of diabetic macular edema (DME). So far, central retinal thickness (CRT) is the most commonly used measure to quantify DME in randomized controlled trials and by retinal physicians in clinical practice. However, various studies showed that CRT has a modest correlation with visual acuity in DME and this relation is sometimes paradoxical. This...

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Retinal Vein Occlusion: Can it be Due to Vasculitis?

Retinal Vein Occlusion is the one of the most important causes for vision loss due to retinal conditions. Most of the time it is due to some associated systemic factors. Vascultis should be suspected in younger age groups with vein occlusions especially where no contributory systemic factors are present. Vasculitis as a disease presents with varied types of manifestations. Retinal vasculitis usually occurs in young patients with the...

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Bilateral Simultaneous Branch Retinal Artery Occlusion by Septic Emboli in Klebsiella Pneumoniae Endogenous Endophthalmitis: A First Case Report

Ah Ran Cho_SCIENTIFIC POSTER 2015 A branch retinal artery occlusion (BRAO) by a septic embolus in bacterial endogenous endophthalmitis has not been previously reported. The authors present the first case of a patient with bilateral simultaneous BRAO by evident septic emboli as a complication of nephrogenic Klebsiella endophthalmitis. A 50 year-old Asian female with a history of type 2 diabetes mellitus transferred to a tertiary care...

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Efficacy of Three Monthly Injections of Ranibizumab for ME Secondary to BRVO

11 dec 2013 … purchase viagra online buy fluoxetine 10 tulsa usa free viagra sample pills cheap fluoxetine in the uk fluoxetine by mail order fluoxetine online without prescription in canada and save money! online buy viagra. affordable viagra – Kateryna Chui_SCIENTIFIC POSTER 2015 Purpose: To assess the efficacy of the three monthly injections of ranibizumab for the treatment of macular oedema (MO) secondary to branch retinal...

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Anatomical & Functional Results After Different Treatment Modalities in Serous Macular Detachment Accompanying DME

Mehmet Demir_SCIENTIFIC POSTER 2015_1 Aim: To investigate the effect of application of a variety of treatment modalities on central macular thickness (CMT), serous macular detachment height (SMD) and best corrected visual acuity (BCVA) in diabetic macular edema (DME) with serous macular detachment. Methods: Eighteen eyes of 15 female and 20 eyes of 13 male Type 2I diabetic patients with DME and SMD applied to Retina Clinic were included in...

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Triamcinolone Versus Ranibizumab Intravitreal Injection Combined with Grid Laser Photocoagulation in the Management of Diffuse DME

The present study was conducted at Mansoura Health Insurence Hospital, Mansoura, Egypt. The study included 136 eyes diabetic patients, 80 males 56 females. All eyes had diffuse diabetic macular edema (DME). The best corrected visual acuity was tested. Fluorescein angiography (FA) and OCT were preformed. The 136 eyes were divided into two groups. Group I included 72 eyes which were subjected to intravitreal injection of triamcinolone (4 mg,...

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Flucinolone Acetate Intravitreal Implant in the Treatment of Persistent and Chronic DME. A Tertiary Multicentre Study

Introduction: Diabetic macular oedema (DMO) is a well known complication of diabetes. Until the last decade argon laser was considered the gold standard treatment of clinically significant macular oedema. Recent landmark studies (READ2, RESTORE, Relight, DRCR.net protocol I) shifted the focus of treatment towards intravitreal injections of anti-VEGF. However, anti-VEGF showed a limited effect in chronic CMO. The FAME study revealed...

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Posterior SubTenon Triamcinolone Acetonide Treatment in DME Cases

Burak ERDEN_SCIENTIFIC POSTER 2015 Aim: To evaluate the efficacy and safety of posterior subTenon triamcinolone acetonid injection in diabetic macular edema cases Material/Method: 13 eyes of 12 diabetic macular edema patients ( 7 M, 5 F ) were enrolled into this retrospective study. 40 mg triamcinolone acetonide was injected into the subTenon space via blunt tip cannula through a minor conjunctival incision in the inferonasal quadrant...

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Clinical Features According to the Diurnal Blood Pressure Variation in BRVO

Hyunwoong Kim_SCIENTIFIC POSTER 2015 Objectives: To investigate clinical features according to the diurnal blood pressure variation in branch retinal vein occlusion (BRVO) using 24-hour ambulatory blood pressure monitoring (24-hour ABPM). Methods: 24-hour ABPM was performed in patients with BRVO. The non-dipper was defined as a nocturnal systolic blood pressure (SBP) decrease less than 10%. Retinal vein occlusion site in fluorescein...

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Algorithm of Surgical Treatment & Rehabilitation of Patients with Tractional RD and ME in Diabetes Type I

Actuality: Proliferative diabetic retinopathy (PDR) is one of the most common complications of diabetes type I. Proliferative retinal changes lead to a sharp vision reduction and, consequently, loss of life quality in young able-bodied patients. Modern technology of vitreoretinal surgery can be successfully used to eliminate the effects of the proliferative process in an eye and improve vision up to its full recovery. However, in most...

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Factors Affecting Functional Outcome of Vitrectomy for PDR

Aim: To determine the factors which influence on the functional outcome of treatment after vitrectomy in patients with proliferative diabetic retinopathy (PDRP). Material & Methods: The study involved 56 patients (56 eyes) with PDRP in time of 2 months after vitrectomy. There were included patients with achieved positive anatomical outcome of treatment, the absence of residual macular edema by optical coherence tomography investigations...

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Neuroretina Degeneration After Vitrectomy for PDR with Vitreous Hemorrhage & Tractional RD

Aim: To compare the degree of neuroretinal degeneration by the complex of electrophysiological methods, pattern visual evoked potentials (PVEP) in patients with proliferative diabetic retinopathy (PDRP) who underwent vitrectomy due to only vitreous hemorrhage and tractional retinal detachment. Material & Methods: We examined 43 patients with PDRP (43 eyes) in terms of 2 months after vitrectomy. The study included patients with positive...

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Changes in Macular Appearance in OCT After Diabetic Vitrectomy

Jae Pil Shin_SCIENTIFIC POSTER 2015_2 Purpose: To classify the changes of macula with optical coherence tomography (OCT) and to analyze the visual prognosis according to the macular appearance in OCT after diabetic vitrectomy. Methods: We reviewed medical records of 60 eyes (56 patients) who had diabetic vitrectomy and had gradable OCT examination before and after surgery. We categorized OCT findings into several groups and analyzed visual...

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Intravitreal Dexamethasone Implant for Chronic DME Resistant to Ranibizumab Injections

Nil İrem Uçgun_SCIENTIFIC POSTER 2015 Purpose: To assess the effect of intravitreal dexamethasone (DEX) 0,7 mg implant (Ozurdex) in patients with chronic diabetic macular edema resistant to prior intravitreal (IV) monthly 5 dose Ranibizumab. Materials & Methods: Twenty five eyes of 24 patients were included the study. Before and after IV DEX implant visual acuity, central macular thickness (CMT) and intraocular pressure (IOP) were...

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Surgical Embolectomy for Branch Retinal Artery Occlusion

Purpose: To report a clinical case of surgical treatment of acute hemi-central retinal artery occlusion. Methods: A 52 years old female with hemi-central retinal artery occlusion due to calcific emboli (CE) on her right eye (RE) was operated on the 7th day after the event. The combined procedure that included phacoemulsification, intraocular lens implantation, pars plana vitrectomy and embolectomy followed fluid/air exchange was performed....

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Vitrectomy in Treatment Naive Diabetic Macular Edema

This movie presents the idea behind vitrectomy in treatment naive diabetic macular edema with and without epiretinal membranes. Surgical technique with ILM peeling will be demonstrated in multiple cases. Everything will be documented with SD-OCT and Swept Source OCT images. Intrasurgically, vitreomacular traction is present in most cases of diabetic macular edema, even if not visible in OCT images. Finally, surgical anatomic and functional...

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Cilioretinal Artery Occlusion with Non Ischemic Central Retinal Vein Occlusion

Maha Shahin_RETINA PHOTO 2015 A healthy 40-year-old man with history of amaurosis fugax in the left eye. 2 days later, he developed scotoma. Examination revealed retinal whitening along the course of one of the cilioretinal arteries and scattered retinal hemorrhages. On fluorescein angiogram of the affected eye, the cilioretinal arteries filled normally. There was marked delay in the filling of the central retinal vein. The patient had no...

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Combined Ranibizumab + Laser Photocoagulation for ME Secondary to BRVO

SCIENTIFIC POSTER_Kateryna Chui baclofen no rx no rx baclofen cod delivery oral baclofen baclofen iv pump order baclofen purchase prednisolone online – safe pharmacy. buy prednisolone online no prescription . buy without a prescription prednisolone 5mg . prednisolone  overnight cod where to buy baclofen rx saturday shipping nebraska prednisone cost walmart prednisone cost walmart buy prednisone online Purpose: To investigate...

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Young EVRS Course: Treatment of DME

                    Exerts: Didier Ducournau & Paul Tornambe Young EVRS Course is dedicated to ophthalmologist at the beginning of their carriers. The course is intended to serve as the forum for asking questions and getting valuable answers. World class experts Didier Ducournau and Paul Tornambe will be gathered to present the topics. So prepare your questions and grill the...

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Retinal Inflammation and DME: Novel Approach

Media not available due to technical recording problems. EVRS is very sorry for the inconvenience.   Objectives: To evaluate the efficacy of topical nepafenac in patients with impaired blood-retinal barrier (BRB) in the macular area. Methods: In a prospective pilot study 15 eyes were included; in the first visit and controls complete eye examination was performed (mean follow-up: 79 days). Visual acuity (VA), central thickness (CT) and...

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577nm Yellow Laser vs 532nm Green Laser for DME

Media not available due to technical recording problems. EVRS is very sorry for the inconvenience.   Advantages: Macular photocoagulation is a standard of care therapy for Diabetic macular edema and it is desirable to use a laser wavelength that is least noxious to the macular tissue. We present our study and concept, suggesting that Yellow laser (577 nm) be used a safe and efficacious alternative to the standard Green Laser (532nm) as...

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Subthreshold Diode Micropulse Photocoagulation for Significant DME

Media not available due to technical recording problems. EVRS is very sorry for the inconvenience.   Purpose: To assess effect of micropulse diode laser (MPDL) on best corrected visual acuity (BCVA) and central foveal thickness (CFT) in treatment of clinically significant diabetic macular oedema (CSME) as compared to conventional argon green laser (CGL) treatment. Design: Single-center, prospective, interventional, comparative...

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My Way Treating Diabetic Retinopathy in a Vitrectomized Eye

Media not available due to technical recording problems. EVRS is very sorry for the inconvenience.   With either diabetic macular edema or with proliferative retinopathy we should ascertain that all retinal laser treatment needed has been done and above all emphasize the importance of a good metabolic control to achieve good results. We certainly should not give up and use anti-angiogenic or corticosteroid intra-vitreal injections as...

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Threshold Laser for Perifoveal Teleangiectasies

Media not available due to technical recording problems. EVRS is very sorry for the inconvenience.   Macular edema due to perifoveolar teleangiectasies is difficult to treat when the TAE are located close to, or at the border of the FAZ. Advantages: Encouraged by the good results of the stimulation treshold or subtreshold laser in CSC without visible focus (we presented this method at the EVRS meeting in Sevilla), we use this treatment...

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Ranibizumab vs Ranibizumab + Laser vs Bevacizumab in the Treatment of Threshold ROP

Media not available due to technical recording problems. EVRS is very sorry for the inconvenience.   Purpose: The aim of the study is to compare the efficacy of intravitreal ranibizumab injection, intravitreal ranibizumab injection combined with retinal laser ablation, and intravitreal bevacizumab injection in treatment of zone and posterior zone 2 severe threshold retinopathy of prematurity (ROP). Patients and methods: A...

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Pars Plan Lensectomy + Vitrectomy in Stages 4 and 5 ROP

Media not available due to technical recording problems. EVRS is very sorry for the inconvenience.   Advantages: Stages 4 and 5 ROP represent a severe form of ROP resulting in visual blindness. Pars plana lvitrectomy with or without lensectomy may offer a dismal prognosis in fixing the retinal detachment. Methods: A series of 15 consecutive cases of severe tractional retinal detachment and falciform folds presenting as stages 4 (8...

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Eight Years Experience with the Use of Bevacizumab in ROP

Media not available due to technical recording problems. EVRS is very sorry for the inconvenience.   Objectives: To report the ocular outcome in retrospective consecutive case series of Type I ROP (stage 3+) who had intravitreal injection of avastin as treatment for acute ROP. Methods: Retrospective review of 32 premature infants clinical cases (50 eyes) who received 0,03 cc of intravitreal bevacizumab as adjuvant treatment for laser...

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Management of Postvitrectomy Vitreous Hemorrhage in Patients with PDR

Media not available due to technical recording problems. EVRS is very sorry for the inconvenience.   Post vitrectomy vitreous hemorrhage is the main cause of failure in patients with proliferative diabetic retinopathy, the rate of this complication is 25 -65% of cases. Most of surgeon usually perform vitrectomy again, sometimes with gas tamponade for haemostatic effect. We propose to do more easy procedure – outpatient fluid gas...

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Endodiathermy Probe as an Aid to Membrane Delamination in Diabetic Traction RD

Media not available due to technical recording problems. EVRS is very sorry for the inconvenience.   Purpose: Eyes with diabetic traction detachment (DTRD) can differ in severity. Systemic control and medication is also very important, which may play a role in the intraoperative and postoperative follow-up. One important complication during surgery is bleeding; when cannot be contolled effectively during pars plana vitrectomy, can...

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Bi-linear Aspiration Flow & Cutting Frequency Control and Segmentation in PDR

Media not available due to technical recording problems. EVRS is very sorry for the inconvenience.   Different techniques have been described for the dissection of proliferative diabetic retinopathy (PDR). When there is a strong adherence between the fibrovascular proliferation and the retinal vessels, segmentation is a safe technique to reduce the risk of bleeding and retinal tear. With the advance of vitrectomy machines, the control...

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Advanced PDR: Surgical Approach

Media not available due to technical recording problems. EVRS is very sorry for the inconvenience.   Methods: Preoperative Avastin 24 hours Always Bimanual approach For dissection I use: a 23G vitreous cutter, Scissors, Fashioned 23G Pick. I use the lower temporal trocar sometimes- in cases with dense fibrovascular proliferations in the upper retina. the working trocars in these cases are the lower temporal and upper nasal The membrane...

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Change of Microaneurysm in Diabetic Retinopathy Patients Who Undergo Bevacizumab Injection

Purpose: To evaluation of microvasular change(microaneurysm) in diabetic retinopathy patients who undergo intravitreal bevacizumab injection by FAG(fluorescein angiography). Method: Thirty- one eyes of 31 diabetic retinopathy patients undergoing intravitreal bevacizumab injection(1.25mg/0.05ml) only one eye were included in this study. The control group(31 eyes) were the opposite eyes. We made an exception for both intravitreal bevacizumab...

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Treating RVO with a Sequential Treatment

Purpose: To evaluate the efficacy and safety of combination therapy with intravitreal ranibizumab followed by dexamethasone implant as compared to dexamethasone implant alone in treating macular edema (ME) due to retinal vein occlusions (RVO). Methods: Retrospective, comparative study. Results: 18 patients had intravitreal ranibizumab followed by dexamethasone implant within 6 weeks of injection (group 1), 19 patients had dexamethasone...

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Vascular Findings in Eyes After Intravitreal Injection of Bevacizumab for ROP

Purpose: To report vascular findings in eyes that had primary treatment with intravitreal bevacizumab for acute ROP (type I stage 3+ ROP). Methods: Retrospective review of 22 infants (32 eyes) that had primary treatment with intravitreal bevacizumab for Type I (stage 3+) ROP. Of those, fourteen (22 eyes) had Zone I or Posterior Zone II ROP and 8 (10 eyes) had Zone II ROP. The minimum follow-up is 1,5 years and the maximum is 6,5...

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Patients Demographics, Ocular Co-pathology & Results for RVO with ME Treated with Ozurdex

The purpose of this work is to describe patients’ demographics, existing ocular co-pathology and treatment procedures for patients treated with Ozurdex for macular oedema due to branch and central retinal vein occlusion in the UK National Health Service (NHS). A multicenter national database study of prospectively collected anonymized data within an electronic medical record system (Medisoft). Data from participating 15 NHS centres across...

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Early vs Late Treatment of ME Due to BRVO with Either Ranibizumab or Bevacizumab

SCIENTIFIC POSTER_Sezin Ozdogan Erkul_1 In this study we wanted to compare efficacy and safety of bevacizumab and ranibizumab in treatment of macular edema due to branch retinal vein occlusion depending on the duration of macular edema. An institutional review board approved retrospective survey was done among 58 eyes of 57 patients having macular edema due to branch retinal vein occlusion. Patients were grouped according to the initial...

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Dexamethasone Implant vs Ranibizumab for RVO with ME : Efficacy Comparison

SCIENTIFIC POSTER_Chi Fung Ernie Lo Background: To evaluate the efficiency of Dexamethasone implants to Ranibizumab injections in macular edema secondary to retinal vein occlusion (RVO) in clinical setting. Design: This is a retrospective comparative cohort study Participants: 44 eyes of 44 newly diagnosed patients with macular edema secondary to either branch retinal vein occlusion or central retinal vein occlusion. Included patient...

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Coats Disease Treated with PPV, Scleral Buckle and Intravitreal Anti-VEGF : A Case Report

Purpose: To report the results of of PPV, scleral buckling and anti-VEGF injections in a patient with Coats disease. Method: Patients data include ophthalmologic evaluation, surgical procedure documentation, OCT and fundus imaging. Results: A 15 years-old boy was referred to our department with leucocoria and low vision. BCVA was 1.0 in right eye and hand movements in left eye, IOP 12 and 8 mm hg respectively. Fundus examination revealed...

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Vitrectomy in Diabetic Macular Edema

For many years, pars plana vitrectomy with posterior hyaloid detachment and peeling of internal limiting membrane (ILM) has been considered a treatment option for diabetic macular edema by retina surgeons worldwide. The 2012 large scale study by EVRS surgeons showed that the surgical option alone resulted, by far, in the most significant visual acuity improvement. However the surgical treatment has, so far, failed to gain widespread...

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PDR : Small Gauge Vitrectomy For Complex Cases

Advantages: Small-Gauge transconjunctival Vitrectomy is a minimally invasive surgical technique. The recent advances in instrumentation have helped to improve the safety and efficacy of surgical technique for Diabetic Retinopathy for Complex Cases. Methods: The video we present, highlights the various spectrum of surgical techniques we can use to treat severe Proliferative Diabetic Retinopathy. The video shows our experience and the...

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Small-gauge Endodiathermy Probe As An Aid to Elevate Tractional Membranes in eyes with Diabetic Traction Retinal Detachment

Purpose: Diabetic traction detachment (DTRD) can differ in severity. Systemic control and medication is very important and may play a role in intraoperative and postoperative follow-up. One important complication during surgery is bleeding; when this cannot be controlled effectively during pars plana vitrectomy, it can cause difficulty in membrane dissection, and even complicate the procedure with retinal tear formation. Preoperative...

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My Way of Treating Diabetic ME

Diabetic macular edema is a multifactorial disorder that needs a multimodal and individualized approach. First we must understand the main mechanism behind each particular case (ischemic, inflammatory, tractional or even mixed) and then select the best treatment option. If it is not possible to clarify the main mechanism (which can change with time, as the natural history of this ocular disease) we should always choose the best way that...

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ILM Peeling During Vitrectomy for Tractional DME. My Way

I do ERM-ILM peeling by using: Chandelier illumination, aspheric macular contact lens, 23 G needle OR closed tip ILM Forceps for creating the ILM flap, clamping the infusion cannula during the BBG stain injection. Chandelier allows for satisfactory illumination with a free second hand that stabilizes the working hand and thus provides stability, precision, control and dexterity. However, positioning and redirecting by the assistant may...

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Unusual Ocular Pretrombotic Syndrome

RETINA PHOTO_Javier Placeres Images showing retinal hemorrhages at different levels (three of them in the subhyaloid space, many of them in the intraretinal space and combined hemorrhages in areas of posterior vitreous detachment).

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Weird Embolus in a Patient with Mechanical Mitral Prosthesis

RETINA PHOTO_Monica Loureiro Color fundus photo of right eye with inferior branch retinal artery occlusion by an embolus, whose characteristics may represent prosthesis material?

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Coats-like Disease Associated with Translocation

RETINA PHOTO_Israel Gomez Sanchez A girl of 13 with multiple congenital anomalies and Hypomelanosis of Ito (Pigmentary mosaicism). Feature a fundoscopy with; teleangiectasia, exudation associated to foveal scar and hypomelanic patches of retina. This hypomelanic patches, hyperfluorescent in fluorescein angiography (window effect) correspond congruently with hypomelanic skin...

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Dexamethasone Implant in a Pregnant Woman for the Treatment of ME in CRVO

Poster Jesus Zarallo Gallardo Introduction: There are several retinal diseases that may worsen or alter during pregnancy as a result of hematologic, hormonal, metabolic, cardiovascular, and immunologic changes. Although normal pregnancy and its hypercoagulable state may induce retinal vein occlusion, hereditary or acquired changes in hemostatic factors increase the risk of thromboembolic events. The risk of venous thromboembolism in...

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The Availability of 24-hour Ambulatory Blood Pressure Monitoring in the BRVO

Poster Il Han Yun Purpose: Hypertension is a major risk factor of retinal vascular occlusion. Generally, blood pressure (BP) has a tendency of fluctuation increased with activity and decreased at night or rest. Especially, non-dipper status is thought to be of clinical and prognostic relevance to target organ damage (TOD) in many studies. So we took part in a measure the 24-hour ambulatory blood pressure monitoring (24hour ABPM) in...

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Removal of the Internal Borderline Membrane in DME Treatment

buy zyban nline canada. buy zyban nline uk. buy cheap zyban nline. rder zyban n prescriptin. nn-prescriptin zyban. zyban nline n prescriptin. zyban generic … Poster Olga Yevsyukova apr 4, 2012 – most of the dramatic side effects occur rarely, buy zoloft from mexico, zoloft online cod , zoloft maximum dosage, three weeks apart. price advair diskus generic name of advair diskus order fluticasone Topicality of the...

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Combined Tractional and Rhegmatogenous RD in Diabetic Patients

Poster Zbiba Walid Goals: The aim of our study was to evaluate the clinical characteristics, the results of surgery and the functional prognosis factors of combined tractional and rhegmatogenous retinal detachment in diabetic patients. Methods: Retrospective study of 32 eyes of 32 diabetic patients who underwent vitrectomy for combined tractional retinal detachment. Extension of fibro vascular proliferation was classified according to its...

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Comparison of Clinical Outcomes of 25 and 23 Gauge Vitrectomy for PDR

Poster Mehmet Onen Purpose: To compare anatomical and functional outcomes of 25 gauge and 23 gauge transconjunctival sutureless vitrectomy (TSV) for treatment of proliferative diabetic retinopathy (PDR). Methods: Retrospective review of 81 consecutive eyes from 81 patients undergoing 25 gauge and 23 gauge TSV with a minimum of 6-month follow-up (vitreous hemorrhage (VH), n=51; tractional retinal detachment (TRD), n=30). Vitrectomy was...

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MH After Intravitreal Ranibizumab Injection for DME

Poster Jaeryung Oh Purpose: To report a case of macular hole formed after intravitreal ranibizumab injection in diabetic macular edema. Case summary: A 76-year-old woman with a 30-year history of type 2 diabetes visited the clinic presenting with the complaint of decreased vision in her right eye. The best-corrected visual acuity of the right eye was 6/20, and 6/12 in the left eye. Intraocular pressure was 20 mmHg in her right eye and she...

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The Change of Macular Thickness Measured by OCT in Diabetic Patients

Advantages: To demonstrate the change in macular thickness using optical coherence tomography in diabetic patients and to assess its relationship with glycosylated hemoglobin (HbA1c) levels and hypertension state. Methods: Diabetic patients who underwent at least two macular thickness measurements with OCT within a 12-month period were include d. HbA1c values within 1 month of each OCT study, and clinical data such as age, insulin...

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OCT Findings in Central Retinal Artery Occlusion

The author describes optical coherence tomography (OCT) findings in a patient with central retinal artery occlusion by conducting a retrospective review of one case. Central retinal artery occlusion shows a distinct pattern on OCT images. In the acute phase, OCT images demonstrate the increased reflectivity and thickness of the inner retina and a corresponding decrease of reflectivity in the outer layer of the retina and retinal pigment...

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Clinical Outcomes According to Silicone Oil Removal Timing in PDR

Advantages: To evaluate the visual prognosis and the occurrence of complications after different terms of silicone oil removal (SOR) in proliferative diabetic retinopathy (PDR). Methods: 21 patients who underwent SOR less than 3 months and 12 patients more than 6 months were included in this retrospective study. The length of silicone oil retention in the eye, visual acuity (VA) and intraocular pressure (IOP) prior to the SOR procedure...

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Comparison of the Axial Length Measurement by Partial Interferometry and Sonography in the Retinal Vein Occlusion

Poster Jung Yeul Kim Purpose: To investigate the axial length of the retinal vein occlusion using contact A-scan sonography and partial interferometry. Participants: The Nineteen patients diagnosed of acute retinal vein occlusion with macular edema and the 24 patients diagnosed of chronic retinal vein occlusion without macular edema. Methods: The central macular thickness was measured by optical coherence tomography. The axial length was...

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Intravitreal Triamcinolone Versus Bevacizumab for Treatment of Subretinal Fluid in Diabetic Retinopathy

Poster V. Levent Karabas Purpose: To evaluate the efficacy of intravitreal triamcinolone acetonite (IVT) injection versus intravitreal bevacizumab (IVB) injection in the management of subretinal fluid in patients with diabetic retinopathy. Methods: Forty-seven patient affected by diabetic macular edema with subretinal fluid were included. Patients were assigned randomly to two groups. IVT group, patients who received 4mg/0.1ml...

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Transpupillary Thermotherapy for Coats’ Disease with Multiple Macroaneurysms in the Posterior Pole

Poster 4 Salim Ben Yahia Advantages: To report clinical findings and outcome of an atypical case of Coats’ disease in an adult patient. Methods: A 48-year-old female underwent ocular examination including dilated fundus examination, fluorescein angiography, and optical coherence tomography. Effectiveness / Safety: The patient presented with decreased vision in her left eye. Fundus examination revealed multiple macroaneurysms in the...

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Macular Photocoagulation Assisted by Intravitreal Bevacizumab (IVB) Versus Triamcinolone (IVTA) in Diabetic Macular Edema with Serous Macular Detachment

Advantage: Diabetic macular edema (DME) with serous macular detachment (SMD) responds poorly to laser treatment due to presence of subretinal fluid but has been seen to resolve following both IVB and IVTA. Re-injections maybe required owing to their limited period of action. We, thus, compared the efficacy of IVTA and IVB followed by laser photocoagulation, in treating DME with SMD. Methods: In this prospective interventional case...

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Intravitreal Diclofenac for Macular Edema (ME) in Branch Retinal Vein Occlusion (BRVO)

Advantage: Various modes of pharmacological intervention like posterior subtenon triamcinolone, intravitreal triamcinolone and bevacizumab, have been seen to be useful in macular edema in BRVO. However, use of triamcinolone has risk of cataract and glaucoma development while bevacizumab is an expensive drug. Intravitreal diclofenac has been found to be effective in decreasing diabetic macular edema but has not been used in macular edema...

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The Appropriate Timing of Pars Plana Vitrectomy After Pretreatment with Intravitreal Bevacizumab for Proliferative Diabetic Retinopathy

Purpose: The purpose of this study was to determine the appropriate timing of pars plana vitrectomy after pretreatment with intravitreal bevacizumab (IVB) for proliferative diabetic retinopathy using histopathological examination of epiretinal membrane biopsies. Material & Methods: This prospective study was conducted in Maghrabi Eye Hospital & Kuwait University Hospital, Sana, between January 2009 – May 2010. Forty...

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Pars Plana Lensectomy / Vitrectomy in Stages 4 and 5 ROP

Stage 5 ROP is a severe form of ROP resulting in retinal detachment and visual blindness. Pars plana lensectomy vitrectomy may offer a dismal prognosis in fixing these detachments.

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Efficacy and Safety of Intravitreal Bevacizumab Monotherapy for Threshold Retinopathy of Prematurity

The introduction of Intraocular Anti-VEGFs agents have significantly improved the management of a wide variety of neovscular ocular diseases including retinopathy of prematurity (ROP). In our hands, monotherapy treatment with intravitreal bevacizumab (IVB) is a favourable treatment modality in management of threshold ROP. In eyes with iris rubeosis, rigid pupils and vitreous haze where it is difficult to visualize the fundus and perform...

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23 Gauge Probe Surgery in Severe Proliferative Diabetic Retinopathy

Technological advances in 23 gauge probe design and vitrectomy machines, allowed the use of the probe to perform many intraoperative techniques and manipulations during complex diabetic vitrectomy. The aim of this work is to describe techniques for using the 23 gauge vitrectomy probe to manage complex diabetic vitrectomy. 120 eyes with severe complications of proliferative diabetic retinopathy were included in this work. They include cases...

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Diabetic Retinopathy

Introduction: Diabetes mellitus is the most common cause of proliferative vascular retinopathy, which also includes retinal venous occlusive disease, Sickle cell retinopathy and retinopathy of prematurity. The underlying abnormality in these disorders is retinal ischemia, which may ultimately lead to the formation and contraction of proliferative fibrovascular membranes with subsequent vitreous hemorrhage and/or retinal detachment. In...

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Limited Surgery in Diabetic Retinopathy

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The EVRS Macular Edema Study Results

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The Effectiveness and Safety of Triamcinolone Injections in DME

Advantages: Intravitreal triamcinolone injections turned out to be effective in reducing macular edema and improving vision in refractory DME after a laser treatment or even as an initial treatment. The steroid-related adverse events, e.g. cataract and elevated intraocular pressure, should be weighed against the benefits of the treatment. Methods: Twenty-mg triamcinolone acetonide intravitreal injections (IVTA) were applied to 110 DME...

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Effectivity of Intravitreal Triamcinolone Injections for Diabetic Cystoid Macular Edema

Persistent diffuse macular edema (ME) or cystoid ME is a result of chronic inflammation with the generalized breakdown of the inner blood retinal barrier and fluid accumulation, primarily in the outer plexiform layer. This process is characterized by the development of hard exudates and progressively lost of vision. Triamcinolone acetonide is the most effective anti-inflammatory agent. After injection into the vitreous cavity...

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Comparison of Endovitreal Triamcinolone with Betamethasone in DME

Advantages: Use of intravitreal injection of crystalline corticosteroids- bethamethasone and triamcinole dose of 4 mg in 0.1 ml allows to improve visual acuity and restore adequate morphological retinal thickness in patients with diffuse diabetic macular edema. Methods: Comparison of efficacy and safety of intravitreal injection of 4 mg (0.1 mL) triamcinolon (36 patients – 40 eyes) and 4 mg (0.1 mL) bethamethasone (60 patients...

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Fluocinolone Acetonide Implants for the Treatment of Chronic DME

Advantages: Given the chronic nature of diabetic macular edema (DME), an implant (ILUVIEN®) that releases a continuous, submicrogram daily dose of fluocinolone acetonide (FAc) could fill an unmet need for continuous long-term therapy. Methods: The Fluocinolone Acetonide in Diabetic Macular Edema (FAME) study consisted of 2 randomized, prospective, multicenter, double-masked, sham-controlled, parallel-group phase 3 trials enrolling...

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Micropulse Contiguous Grid Laser for Resistant Diffuse DME

Purpose: To investigate micropulse contiguous grid laser (MCGL) for DDME involving the fovea, and to correlate OCT findings with resolution target visual fields (RTVF) scotomas and global macular acuity (GMA). Methods: One year retrospective review of sequentially treated eyes including, OCT, FA, RTVF and NEI-VFQ 25. Results: In 56 eyes GMA improved 0.2 logMAR in 34%, with none worsening >0.3 logMAR. Central OCT decreased 173 µm+9.3....

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Effectiveness of Combined Betamethasone and Laser Coagulation for DME

Advantages: Combined treatment of diffuse diabetic macular edema using intravitreal injection of bethamethasone and laser coagulation is effective in improving visual acuity and restoration of the morphofunctional state of the retina. Methods: Intravitreal injection 4 mg (0.1 ml) of bethamethasone combined with laser coagulation was conducted in 33 patients (33 eyes) with diffused diabetic macular edema. Patients were divided into 2...

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Micropulse Laser Following Intra Vitreal Bevacizumab in Diffuse DME

Advantages: Intravitreal bevacizumab followed by laser micropulse in CSME offers a clear advantage of non-inducing a visible retinal burn and having a potential efficiency in reducing foveal thickness and visual acuity Methods: Prospective case series. One hundred and twenty cases of non-ischemic non-tractional CSME with macular thickness more than 400 microns as defined by OCT were managed by initial intravitreal bevacizumab injection...

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Micropulsed 577 nm Laser Stimulation for DME

Advantages: Laser stimulation seems to be effective, safer, non-tissue harmful and cost effective to treat diabetic macular edema. Methods: Eighty-eight eyes of 78 diabetic patients with DME were treated with yellow diode laser (577 nm) suited for micropulse treatment in macular area. ETDRS best corrected visual acuity, High definition optical coherence tomography to determine central macular thickness, Fluorescein angiography (FA) and...

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Aflibercept (VEGF Trap Eye, Eylea) for Treatment of Diabetic Macular Edema

Advantages: Aflibercept (VEGF Trap Eye, Eylea) has a longer duration of action compared to ranibizumab (Lucentis). Methods: Randomized clinical trials. Effectiveness / Safety: In a phase II trial patients with diabetic macular edema gained 9.7 letters with aflibercept every 8 weeks and 13.1 letters with aflibercept every 4 weeks.  Phase III trials, VISTA and VIVID, are underway. Take home message: Aflibercept may be an effective...

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Treatment of Diabetic Macular Edema with Ranibizumab

Advantages: Intravitreal ranibizumab improves vision of patients with diabetic macular edema. Methods: Review of recent clinical trials such as DRCR.net. Effectiveness / Safety: DRCR trials showed that in patients with diabetic macular edema, intravitreal ranibizumab with prompt or deferred focal/grid laser had superior Visual Acuity outcome compared with focal/grid laser treatment alone. Take home message: Intravitreal ranibizumab is...

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ILM Peeling in Patients with Clinically Significant DME: Long-term Outcomes

Background: Diabetic macular edema (DME) is a frequent complication of diabetic retinopathy. It is characterized to increased vascular permeability, due to blood-retinal barriers breakdown. Since macular laser treatment has shown poor efficacy to diffuse edema, surgical option of therapy is discussed. Several studies have proven the efficacy of pars plana vitrectomy (PPV) with inner limiting membrane (ILM) peeling in case of DME with a...

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Does Vitreous Surgery for Diabetes Complications Have an Influence on the Course of Macular Edema in Long-term Follow-up?

Advantages: To evaluate the influence of vitreous surgery performed for vitreous hemorrhage and traction retinal detachment (macular edema excluded) as a complication of diabetic retinopathy with or without ILM peeling on macular edema formation. Additionally to evaluate long-term spectral domain optical coherence tomography (SD-OCT) follow- up of macular structure. Methods: 101 eyes of patients, who had undergone vitrectomy were...

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PPV in Management of Type 1 Non-tractional DME After Failure of all Therapies

Advantages: PPV is a useful method in management of non-tractional, non-ischemic resistant diffuse diabetic macular edema associated with type 1 DM Methods: Type 1 Diabetic macular edema (DME) is typically managed by thermal laser, intravitreal injections and systemic control. An entity of diffuse DME persists despite all therapies. We present 5 cases of diffuse non-tractional, non-ischemic diffuse DME in type 1 DM managed by clear...

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Vitrectomy Outcome in Resistent Non-tractional Diffuse DME

Advantages: Diabetic diffuse macular edema not responding to repeated IV injctions of Anti-VEGF and/or Triamcinolone may benefit from vitrectomy and ILM peeling. Vitrectomy helps to remove factors and mediators that may play a role in production of macular edema and/or its no or poor response to IV injections. ILM peeling ensure complete relieve of traction and may stimulate retinal glial cells mainly Muller cells to reactive fibrosis and...

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Vitrectomy Outcome in Traction Diffuse DME

Advantages: In eyes with diffuse diabetic macular edema and OCT evidence of tangential and/or anteroposterior traction, Vitrectomy techniques allow complete release of traction, restoration of normal or near normal retinal architecture, and functional improvement. Methods: 65 eyes with traction diabetic diffuse macular edema underwent 23 gauge vitrectomy. All eyes underwent preoperative FA and OCT. Vitrectomy was combined with...

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