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Development of Angioid Streaks in Association with Pseudoxanthoma Elasticum: Report of 5 Cases

SCIENTIFIC POSTER_Jose Alberto Lemos Purpose: Angioid streaks are visible irregular crack-like dehiscences in an abnormal and calcified Bruch’s membrane that are associated with atrophic degeneration of the overlying retinal pigment epithelium. They appear as dark or reddish streaks originating from the optic disc, almost always bilaterally. Angioid streaks have been commonly associated with systemic conditions such as pseudoxanthoma...

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Complementary Angiographic and Autofluorescence Findings in Pseudoxanthoma Elasticum

Pseudoxanthoma elasticum (PXE) is a systemic disease with characteristic findings on fundus examination. The fundus findings may be difficult to detect with ophthalmoscopy. A case report is described as follows. A PXE patient had subtle retinal findings on fundoscopy that were more prominently seen using a combination of both fundus autofluorescence (FAF) imaging and fluorescein angiography. The fundus features visualized using each of...

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Combination Treatment of PDT and Intravitreal Ranibizumab for CNV Secondary to Angioid Streaks – 12-Month Results

Angioid streaks also called Knapp striae are small breaks in the Bruch’s membrane and have been reported with a host of systemic diseases. Rupture of streaks or development of secondary choroidal neovascular membrane (CNVM) carries a dismal visual prognosis. We report the result treatment of CNVM secondary to angioid streaks with combination treatment of photodynamic therapy (PDT) and intravitreal ranibizumab.

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Photodynamic Therapy with Verteporfin Combined with Intravitreal Bevacizumab for Choroidal Neovascularization in Angioid Streaks

Levent Karabas, Hande Etus*, Bengu Yucel, Yusuf Çaglar (Kocaeli, Turkey) Advantages: To evaluate safety and efficacy of photodynamic therapy (PDT) with Verteporfin combined with intravitreal bevacizumab for choroidal neovascularization associated with angioid streaks. Methods: Six eyes of six patients treated with PDT with Verteporfin and 0, 05 mg/ml Bevacizumab injections were included. Standardized protocol, visual acuity (VA),...

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When to Consider Stopping Intravitreal Bevacizumab for the Treatment of CNV Secondary to Angioid Streaks

Leila El Matri, Fedra Kort, Ahmed Chebil, Rim Bouraoui, Najoua Ben Youssef, Mejda Bouladi (Tunis, Tunisia) Advantages: Choroidal neovascularization (CNV) is the most serious complication of angioid streaks. It occurs in young and active people and leads to severe visual impairment. Treatment is difficult and results are often disappointing. Methods: Twenty eyes of 19 patients with subfoveal or juxtafoveal CNV secondary to angioid streaks...

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Intravitreal Injection of Bevacizumab for the Treatment of Choroidal Neovascularization Secondary to Angioid Streaks

Salim Ben Yahia, Rim Kahloun, Salma Gargouri, Rim Ghrissi, Riadh Messaoud, Moncef Khairallah (Monastir, Tunisia) Advantages: To manage choroidal neovascularization (CNV) secondary to angioid streaks with intravitreal injection of bevacizumab. Methods: Eight eyes of 8 patients with CNV secondary to angioid streaks were treated with intravitreal injection of 1.25 mg (0.05 mL) of bevacizumab. Main outcome measures included changes in...

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