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Clinical Experience of Ocriplasmin for Vitreomacular Traction and MH

Purpose: To evaluate the anatomical and functional results after ocriplasmin (JETREA, ThromboGenics NV, Iselin, NJ, USA) injection in patients with vitreomacular traction (VMT) with or without macular hole (MH). Methods: Fifteen prospective patients with VMT were treated with a single ocriplasmin injection and followed-up at baseline, 1 week, 1, 3 and 6 months. ETDRS best-corrected visual acuity (BCVA), intraocular pressure and...

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Outcome of IVT of Ocriplasmin for Symptomatic Vitreomacular Adhesion

SCIENTIFIC POSTER 2016_Outcome of IVTY of Ocriplasmin for Symptomatic Vitreomacular Adhesion Mostafa Elgohary Purpose: To evaluate the rate of release of vitreomacular adhesion (VMA), anatomical changes and visual outcome following intravitreal ocriplasmin injection for the treatment of symptomatic VMA with and without full-thickness macular hole (FTMH). Methods: This is a retrospective, interventional, case-series of 12 eyes of 11...

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Outcome of Vitreomacular Traction Syndrome: Natural Course vs Vitrectomy vs Ocriplasmin

SCIENTIFIC POSTER 2016_Outcome of Vitreomacular Traction Syndrome Natural Course vs Vitrectomy vs Ocriplasmin Constantinos Demosthenous Purpose: Posterior Vitreous Detachment (PVD) is a common eye condition related with the normal aging of vitreous gel. However, the presence of persistent vitreomacular adhesions exerting tractional forces may be associated with the disruption of foveal anatomy thereby causing symptoms of visual...

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Comparison of Clinical Characteristics in Myopic Traction Maculopathy with and Without MH

So Hyun Bae_SCIENTIFIC POSTER 2015 Purpose: To compare the clinical characteristics of myopic traction maculopathy (MTM) with and without macular hole (MH). Methods: This retrospective study included the patients with MTM who underwent vitrectomy. The eyes were subdivided into 2 groups based on the presence of MH. Clinical features were assessed including age, sex, axial length, visual acuity, posterior staphyloma, chorioretinal atrophy and...

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The Efficacy of Ocriplasmin in the Treatment of Symptomatic Vitreomacular Traction

Katarzyna Michalska-Malecka_SCIENTIFIC POSTER 2015 The Aim: The aim of the research was to evaluate the influence of ocriplasmin intravitreal injection on the changes in vitreomacular traction and on improvements in visual acuity. Patients & Methods: The analysis included patients who were treated in the University Centre of Ophthalmology and Oncology, Independent Public Clinical Hospital, Medical University of Silesia in Katowice, and...

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My Tips for Improved Outcomes in Macular Hole Surgery

The authors present “My Way” for Macular Hole surgical approach. Reports in the literature are largely retrospective, making direct comparison of surgical strategies and methods difficult.The authors expose their tips and rationale for surgical approach that they believe is a contribution to improved outcomes. Tip 1 – Idiopathic Macular Holes are actually secondary to Vitreo Macular Traction (VMT) Tip 2 – In macular holes...

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The Role of OCT in Management of VMT

OCT is a prime technique for studying vitreo-retinal interface, from which it is possible to establish the diagnosis of vitreomacular traction. A recently proposed new classification of the pathology of vitreo-retinal interface based on microstructural retinal images provided by SD-OCT allows better discussion about the therapeutic decision. However identifying a diagnosis cannot be the sole basis for treatment decision. The OCT allows us...

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Macular Hole and VMT in Fellow Eye…How to Approach?

A 68-years-old patient,female,with loss of vision in the right eye (count fingers) and symptoms of deterioration visual acuity and distorted vision in the left eye. The OCT showed a full thickeness macular hole in the right eye and a vitreomacular traction in the left eye. The issue in discussion is: The aproach to the right eye. Wich are the options of treatment for the left eye??: Vitrectomy?? Pharmacologic Vitreolysis?? The authors...

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Improvements in Visual Acuity After Treatment of Vitreomacular Traction and Full-Thickness Macular Hole With Ocriplasmin

Advantages: Vitreomacular traction (VMT) is a progressive retinal disorder that can result in visual distortions and loss of vision that until recently did not have a pharmacological treatment option. Phase 3 clinical trials showed that a single intravitreal injection of ocriplasmin (125 µg) results in a significantly higher proportion of patients achieving anatomic resolution of VMT and closure of full-thickness macular hole (FTMH)...

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Efficacy of Ocriplasmin in Patients with Vitreomacular Traction

Background/Advantages: Since May 2013 ocriplasmin (Jetrea, Alcon) has been available on the German market for the treatment of vitreomacular traction (VMT) including when associated with a macular hole of less than or equal to 400 microns. The main aim of this study was to treat a more homogenous group of patients with specific baseline characteristics with ocriplasmin, and to compare the results with those of previous trials. Patient...

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Symptomatic VMT: 27 G Surgical Way vs Injections!

Advantages: In selected cases of VMT, pharmacologic treatment is proposed but the effect is not 100%. The mini MIVS approach obtained complete result but with the risk of surgery and the stimulation of the cataract. My way is a modification of the Oshima technique using a 27 G approach, reflow strategy, slit lamp illumination and only one pars plana port approach with forceps without vitrectomy in this phakic patient. Methods: The use of...

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Natural Course and Surgical Treatment of Vitreomacular Traction Syndrome

Advantages: To present the natural course vs. vitrectomy for macular oedema in vitreomacular traction syndrome. Methods: 52 patients with vitreomacular traction syndrome were examined with mean follow- up of 12 months. Patients had complete ophthalmic examination and spectral domain optical coherence tomography (SD- OCT) on a regular course. Effectiveness / Safety: 15 eyes had vitrectomy performed and 13 had spontaneous resolution of...

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Comparing the Results of ERM and Vitreomacular Traction Syndrome Surgeries

Comparing the Results of ERM and Vitreomacular Traction Syndrome Surgeries Lidmila Prochazkova Advantages: Comparing anatomical and functional results of idiopathic epiretinal membrane (ERM) and vitreomacular traction syndrome (VMTS) surgeries carried out at the Department of Ophtalmology, Masaryk Hospital, Usti nad Labem. Methods: Over the course of 4.5 years 47 surgeries were performed for idiopathic ERM and 15 for VMTS. We have...

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A Single Injection of Ocriplasmin for the Treatment of Symptomatic Vitreomacular Adhesion (sVMA): Results of the Phase III MIVI-TRUST Program

Peter Stalmans for the MIVI-TRUST Study Group (Leuven, Belgium) Purpose: Symptomatic vitreomacular adhesion (sVMA) is implicated in the pathobiology of retinal disorders including vitreomacular traction syndrome and macular hole, and is associated with more severe disease in other conditions such as diabetic retinopathy, DME, and AMD. The MIVI-TRUST program is composed of two Phase III trials evaluating ocriplasmin for the treatment of sVMA...

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Congress – An unusual large tractional macular break

SYMPOSIUM:MACULA POT POURRI Moderator: Khaled El-Rakhawy Sunday, June 19, 2005 An unusual large tractional macular break Author: S. Ben Yahia, S. Jenzeri, B. Jelliti, S. Aouafi, M. Oueld El Hassen, R. Messaoud, A. Ladjimi, M. Khairallah Abstract : Purpose: To describe an unusual case of a large tractional macular break. Methods: Case report. Results: A 38-year-old healthy man presented with a sudden decrease of vision in his left...

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Vitreo-Macular Surgery – Double Edge Sword

http://www.evrs.eu/medias/2010/videos/ChiragBhatt_2_VP6_768K.flv Chirag Bhatt, Aniruddha Maiti, Deepak Sharma, P. K. Chatterjee, R. C. Paul (Kolkata, India) Advantages: Vitreo-macular traction syndrome if treated timely can give encouraging results and if left untreated may lead to chronic CME or even full-thickness macular hole thus leading to reduction of vision in some cases. Methods: We use 23 Gauge transconjunctival sutureless...

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Myopic Traction Maculopathy: A Slowly Progressive and Treatable Disease

http://www.evrs.eu/medias/2006/congress/Myopic-Traction-Maculopathy:-A-Slowly-Progressive-and-Treatable-Disease.swf Giacomo Panozzo, MD (Verona, Italy), Barbara Parolini, MD (Verona, Italy), Andrea Mercanti, MD (Verona, Italy) PURPOSE: Myopic Traction Maculopathy (MTM) is a recently discovered cause of visual impairment in high myopia, generated by the presence of anomalous vitreoretinal traction inside the staphyloma. Development, natural...

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Hypothesis: Is Vitreous Adhesion a Risk Factor for CNV in AMD?

http://www.evrs.eu/medias/2005/congress/Hypothesis:-Is-vitreous-adhesion-a-risk-factor-for-CNV-in-AMD.swf Martine Mauget-Faÿsse, Maddalena Quaranta El Maftouhi, Margara Zanotele, François Devin Purpose: The relationships between posterior vitreous and retina have been poorly described in vivo in exudative AMD. In a previous study (ARVO 2003), high prevalence of abnormalities of the vitreo-retinal interface have been found in exudative AMD...

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25G Vitrectomy for Epiretinal Membranes (ERM) and Vitreo-Macular Traction Syndromes: Short-Term Results

A. C. Gribomont, J. Delescaille Purpose: To evaluate the safety and efficacy of the 25G transconjunctival vitrectomy in the treatment of epimacular membranes and vitreo-macular traction syndromes. Methods: In this prospective study dealing with a consecutive series of 38 eyes with an epimacular membrane or a vitreo-macular traction syndrome, either idiopathic or secondary, we recorded the visual acuity and intraocular pressure the day...

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An Unusual Large Tractional Macular Break

http://www.evrs.eu/medias/2005/congress/An-unusual-large-tractional-macular-break.swf S. Ben Yahia, S. Jenzeri, B. Jelliti, S. Aouafi, M. Oueld El Hassen, R. Messaoud, A. Ladjimi, M. Khairallah Purpose: To describe an unusual case of a large tractional macular break. Methods: Case report. Results: A 38-year-old healthy man presented with a sudden decrease of vision in his left eye. He had no history of ocular trauma. Visual acuity was 20/20...

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