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You Have Got Endophthalmitis! What Next…???

The purpose of this presentation is to highlight significant worldwide issues in relation to Endophthalmitis management. It explores a detailed answer to this question – “What has changed since EVS?”; and highlights profound limitations of EVS, New evidences since EVS and Current Global Retina-Practice-Trends. The author unreservedly defends the role of early or primary vitrectomy in the management of most cases of Endophthalmitis;...

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Endophthalmitis After Intravitreal Drug Injection – A Transatlantic Controversy Regarding Prophylaxis and Treatment

Intravitreal drug application (IVI) has become the most frequent invasive intraocular procedure. Endophthalmitis – although rare with an incidence of 0,04% per injection – is the most devastated complication. Looking back to the initial era of IVI, infectious rates were as high as after cataract surgery. In face of a significant increased individual cumulative risk, antiseptic measures have been introduced and resulted in a marked...

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Ten Consecutive Cases of Endophthalmitis After IVT of Bevacizumab

Purpose: The purpose of this study is to report 10 consecutive cases of endophthalmitis after intravitreal injection of bevacizumab (avastin; roche) obtained from a single batch. Methods: One vial of bevacizumab (100mg/4ml) was used to take 10 sterile injections and aplied in the same moment that was taken from the batch. Bevacizumab (1.25mg/0.05ml) was injected intravitreally into 10 eyes of ten patiens to treat diabetic macular edema,...

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Intravitreal Levoxacin as Initial Treatment of Acute Exogenous Endophthalmitis Before PPV

The authors declare no conflict of interest. Purpose: To report the efficacy of intravitreal levofloxacin as an initial treatment of acute exogenous endophthalmitis on the stage of transportation of the patients to the vitreoretinal department and before early pars plana vitrectomy (PPV). Methods: Thirty patients (34 eyes) with exogenous endophthalmitis were included to this prospective non-randomized study. Fourteen patients (41.2%) had...

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Endoscopy-guided 20G PPV in Severe Endophthalmitis: Literature Review & Report of 18 Cases

Objective: We aim to report the anatomical and functional outcomes after endoscopy-guided vitrectomy, in a series of severe endophthalmitis. We also aim to identify two different clinical presentation modes and to compare the outcomes. Patients & Methods: Retrospective case study, single center, all patients who underwent endoscopic vitrectomy 20ga (Endo optiks E4 system) for severe endophthalmitis were included. For each case, data...

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Endophthalmitis – Immediate Intravitreal Antibiotic Therapy Only is What We Should Do

The Endophthalmitis Vitrectomy Study (EVS) has recommended that intravitreal antibiotics should be the ‘‘standard of care’’ for acute endophthalmitis occurring after cataract surgery and that the benefit of early vitrectomy surgery is limited. However, with recent advances in vitrectomy surgery techniques, there has been an increased interest in performing early vitrectomy surgery to treat endophthalmitis in...

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