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TTT-like Laser Coagulation of Peripapillary Neovascular Membranes

In eyes with AMD or other choroidal pathologies prone to develop subretinal neovascular membranes we occasionally encounter cases where the CNV is localized around the optic disc, giving rise to an exudative retinal detachment frequently involving the macula and reducing visual function. When the CNV does not involve the foveal zone directly, anti-VEGF therapy is not indicated, although it might be effective. Many will be hesitant to use...

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Gloucestershire Model for Treating Neovascular ARMD – An Industrial Production Line!

The management of patients with neovascular age related macular degeneration (nAMD) forms a large and increasing proportion of hospital eye service activity worldwide, particularly since the introduction of intravitreal anti-VEGF therapy. The delivery of anti-VEGF therapy has created substantial service pressures on ophthalmology departments. Delays in access to timely initial treatment and follow up assessment are widespread in the UK...

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Personalized Medicine Applied to AMD

Introduction: AMD is a multi factorial disease triggered by aging (parainflammation), and genetic, cardio-vascular, inflammatory and environmental factors. The natural history of the disease shows that 80% of neovascular membranes are occult and that their natural course is a succession of relapse and remission phases. Patients and Methods: 45 eyes in 38 consecutive patients with neovascular AMD were treated by intravitreal anti VEGF...

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Reasons for Aflibercept Prescription in Wet AMD in Real Life

Purpose: To describe the main reason for aflibercept prescription in the treatment of exudative age-related macular degeneration (AMD) during the initial weeks of availability of this drug in a clinical setting. Patients and methods: During the first 16 weeks of availability in France, four experienced practitioners in retinal disease detailed the main reason that led to aflibercept prescription. The charts of these patients were reviewed...

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Epiretinal Membranes in Neovascular Age-related Macular Degeneration: Effect on Outcomes of Anti-VEGF Therapy

Introduction: Vitreomacular interface changes of AMD patients such as posterior vitreous detachment (PVD), vitreomacular adhesion (VMA) and vitreomacular traction (VMT) have been addressed in several clinical studies using optic coherence tomography (OCT).However role of epiretinal membrane (ERM) has not been investigated in the concept of vitreomacular interface disorders in nAMD patients. Methods or Study Design: This study is a...

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Primary Combination Therapy for Exudative ARMD

Objective: Efficacy of Primary ICG-directed PDT Triple Therapy with verteporfin (Visudyne), ranibizumab (Lucentis), and triamcinolone acetonide (Triescence) versus €˜Standard of Care, i.e. anti-VEGF monotherapy, for the treatment of Exudative ARMD. Design: Retrospective, non-randomized, exploratory study. Methods: 2 year study of 115 patients (120 eyes) with treatment-naive Exudative ARMD, VA 0.1 to 1.00 LOGMAR units, who were placed into...

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Structural Changes of Choroidal Neovascularization in Indocyanine Green Angiography After Ranibizumab Injection

SCIENTIFIC POSTER_Il Han Yun Purpose: To investigate the mechanism of choroidal neovascularization (CNV) recurrence followed by intravitreal ranibizumab injections based on vascular structural changes of choroidal neovascularization (CNV) using indocyanine green angiography (ICGA) Methods: A total of 31 patients with exudative age-related macular degeneration and CNV whose structures were identifiable in ICGA. Patients with either...

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Morphology of PED as a Predicting Factor of Outcomes for Anti-VEGF Therapy of Wet AMD

SCIENTIFIC POSTER_Elena Kozina OCT-criteria for a potential risk of pigment epithelium (PE) tear development, PE reattaching and PED resistance at A-VEGF therapy of patients with wet AMD, accompanied by high PE detachment are determined retrosprctively for predicting the possible treatment outcome and determination of the optimal mode of A-VEGF injection. General Considerations: In clinical practice the different morphological forms of...

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Two Different Options in the Treatment of Premacular Hemorrhage Secondary to Macroaneurysm

  SCIENTIFIC POSTER_Ines Coutinho Purpose: Premacular hemorrhage is one major cause of sudden visual loss and occurs in a variety of disorders, among others in retinal arterial macroaneurysms (RAM). Possible therapeutic options include observation, vitrectomy, intravitreal rT-PA injection or laser posterior hyaloidotomy. However, the best treatment is still controversial. We report on 2 cases with premacular haemorrhage due to RAM. The...

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Expression Pattern of Extracellular Matrix Components After Ranibizumab for Neovascular ARMD

Poster Malgorzata Nita Purpose: The aim of the study was to evaluate the effect of loading doses of ranibizumab on gene expression of matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs) in patients with CNV/AMD. Setting: Study was conducted by the Department of Ophthalmology, Medical University of Silesia, Independent Public Clinical Hospital, Katowice, Poland. Methods Inclusion criteria: patients ≥60...

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Ocular Adverse Events Related to Intravitreal Ranibizumab in Patients with Exudative ARMD

Purpose: Anti-VEGF injections have been standard treatment of exudative age-related macular degeneration (ARMD) in recent years. However multiple and recurrent injections needed to maintain the efficacy of the treatment may lead to adverse side effects related to this regimen. The aim of this study was to find out ocular adverse events associated with intravitreal injection of ranibizumab for the treatment of exudative ARMD performed in a...

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Retinal Nerve Fiber Layer Thickness Change in Wet AMD Treated with Ranibizumab

Poster Ozen Ayranci Osmanbasoglu Advantages: To assess the effect of intravitreal (IV) ranibizumab therapy on retinal nerve fiber layer (RNFL) thickness. Methods: Fourteen eyes of 11 treatment naive patients with neovascular age related macular degeneration treated with ranibizumab were included. Patients were followed up by monthly examinations and IV ranibizumab injections were done as on needed basis. RNFL thickness s was measured by...

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Morphological Changes in Spectral Domain Optical Coherence Tomography Guided Bevacizumab Injections in Wet AMD, 12-months Results

http://www.dailymotion.com/video/x169htw Advantage: This paper aims to describe retinal changes during Spectral Domain Optical Coherence Tomography (SD-OCT) guided Bevacizumab treatment for neovascular age- related macular degeneration (AMD). Material and Methods: 47 eyes of 45 patients with wet AMD treated on demand with Bevacizumab. We used 3-dimensional SD-OCT to measure photoreceptor defects and subretinal fibrosis. The main efficacy...

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Early Onset Exudative AMD Detected with Monthly SD-OCT with Eye-tracking of the Fellow Eye in Patients Treated with Anti-VEGF

http://www.dailymotion.com/video/x168ujv Advantage: To determine the frequency and characteristic features of new- onset neovascularization (CNV) in age related macular degeneration (AMD) with spectral domain optical coherence tomography (SD-OCT). Methods: Prospective, observational study of 68 patients with unilateral CNV treated with Bevacizumab. SD-OCT and visual acuity (logMAR) was measured at baseline and then monthly in both, the...

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Ranibizumab vs Bevacizumab vs Combined Therapy PDT-Ranibizumab for the Treatment of Age-related Macular Degeneration: One-year Follow-up

http://www.dailymotion.com/video/x16akz9 Advantages: To compare the efficiency of three different treatments analyzing the changes in visual acuity (VA), number of used doses and costs. Methods: In a randomized prospective study we created three groups: Group-A, where we administered 0.5 mg (0.05ml) of intravitreal (IV) Ranibizumab, for three consecutive months; Group-B, where we combined the photodynamic therapy together with an IV...

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Combined Intravitreal Anti-VEGF & Subtenon Corticosteroids in AMD to Reduce ME Recurrence

http://www.dailymotion.com/video/x168ujf Purpose:  To evaluate combined treatment of Anti-VEGF & subtenon corticosteroids for recurrent macular edema (ME) associated to choroidal neovascularization (CNV) due to age related macular degeneration (AMD). Material & Methods: Cases of CNV in AMD were included in this retrospective study. All types of CNV could be included (classic, minimally classic, occult, PEDs) Results: This combined...

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Pedunculated choroidal – RPE Patch Transplantation in Severe Neovascular Macular Degeneration

http://www.dailymotion.com/video/x16c8nv Advantages: To perform an autologous RPE graft in a case of fibrotic CNV leaving a link between the patch and the original site of it. Methods: Standard vitrectomy with induction of retinal detachment and retinectomy of the 180° temporal retina; removal of fibrotic subfoveal fibrotic membrane, preparation of a choroidal patch to move on the macular area leaving a part connected with the original...

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Tachyphylaxis During Ranibizumab Treatment of Exudative Age-related Macular Degeneration

http://www.dailymotion.com/video/x16b23g Purpose: To determine the rate of tachyphylaxis during Ranibizumab therapy for exudative age-related macular degeneration (AMD). Methods: The records of patients treated with Ranibizumab were retrospectively reviewed. Tachyphylaxis was defined as an initial good response to Ranibizumab followed by a decrease or absence of the response to Ranibizumab despite a minimum of two injections du ring...

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Surgical Approach to Massive Subretinal Hemorrhages Secondary to Neovascular ARMD

http://www.dailymotion.com/video/x16b1ss Purpose: Different surgical management of massive subretinal hemorrhage secondary to ARMD will be defined. Methods: Pars plana vitrectomy (PPV) with 360 retinotomy and removal of subretinal hemorrhage and membrane +/- choroidal patch graft is performed to 3 cases of massive subretinal hemorrhage secondary to ARMD and the results and surgical videos will be presented. Take home message: Subretinal...

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Individualized Approach to Neovascular ARMD Treatment

http://www.dailymotion.com/video/x168ya9 Purpose: To define a new approach for treatment of neovascular ARMD cases with less frequent visits and injections. Methods: Neovascular ARMD cases that have been followed-up for 1-2 year period were analyzed retrospectively and those who had regular intervals of recurrence were identified. An individualized visit and injection period was defined for each of those patients...

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CNV in AMD

Autologous RPE and choroid transplantation for the treatment of CNV in AMD will be presented in details. http://www.dailymotion.com/video/x15se2j

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PPV with Choroid-RPE Patch Graft for Massive Hemorrhage Due to Neovascular ARMD

This is a video of a patient with age related macular degeneration who had a macular scar in his right eye and a new subretinal massive hemorrhage causing hemorrhagic retinal detachment in his left eye which used to be his better eye. A cataract surgery combined with pars plana vitrectomy with 360 retinotomy, removal of subretinal hemorrhage, clots and choroidal neovascular membrane, and choroid-retina pigment epithelial patch graft was...

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Removing the Submacular Scar

Submacular scar in long standing age related macular degeneration cases severly compromise the vision and vis a vis the day to day activity of the person thus affected. Minimum improvements in the vision make these patients happier. It helps them with at least the benefit of improved field of vision. Here we describe surgery in a patient with long standing macular scar. Novel instrumentation technique was used to make a sub macular cannula....

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Autologous Transplantation of RPE & Choroid for Wet AMD: Functional Results and Prognostic Factors After a Long-term Follow-up

Advantages: Choroidal neovascularization in age related macular degeneration (AMD), non-responder to standard care, might be treated with autologous transplantation of retinal pigment epithelium and choroid (PATCH). The purpose was to define prognostic criteria for this surgery, to improve the result. Methods: Thirty eyes underwent PATCH surgery. Follow-up was 36 months. Patients received ETDRS, OCT scan and fluorescein and indocyanine...

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Do Neovascular AMD Lesions Associated with PED Behave Differently to Anti-VEGF Treatment?

Purpose: To document the prognosis of eyes with neovascular AMD associated with any pigment epithelial detachment (PED) during the course of anti VEGF treatment. Methods: The medical records of 331 eyes with neovascular AMD treated with intravitreal anti VEGFs were retrospectively errate for the presence of PED. The visual and anatomical (OCT) prognosis of the cases and complication rates after treatment were determined. Results: PED was...

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Proteomics in Exudative AMD

Purpose: To errate and compare vitreous samples of exudative AMD with these of floater patients with PROTEOMICS. Methods: Twenty-three vitreous samples (15 AMD and 8 controls) from patients undergoing 23 gauge single-site core vitrectomy for combined intravitreal treatment were errate with capillary electrophoresis coupled to mass spectrometry. Results: A total of 5949 polypeptides (PP) could be defined in all samples based on mass,...

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Combined Treatment with Sub-tenon Injection of Triamcinolone and Intravitreal Anti-VEGF Injection in Refractory Neovascular ARMD

Advantages: Combined treatment with sub-Tenon’s injection of triamcinolone and intravitreal anti-VEGF injection has beneficial effect in improving visual acuity and anatomic outcomes in refractory neovascular AMD patients. Methods: Seven eyes of 7 patients with refractory neovascular age-related macular degeneration (AMD) secondary to polypoidal choroidal vasculopathy (PCV) were enrolled. Refractory PCV was defined as no response of...

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Relationship of Elevated Osteoprotegerin with Exudative ARMD

Purpose: The aim of the present study was to elucidate if there is any relationship between osteoprotegerin (OPG) and exudative age-related macular degeneration (E-AMD), a disease with similar risk factors as coronary artery disease. Methods: In a cross-sectional study, we compared 45 E-AMD patients with 45 matched controls. Diagnosis was confirmed by fluorescein angiography. Serum samples were analyzed for OPG, RANK Ligand, low-density...

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The Effect of Anti-VEGF Treatment on Fundus Fluorescein Angiographic Findings in AMD Cases

Advantages: To analyse the effect of anti-VEGF treatment on arm to retinal circulation, capillary time, venous filling time, retinal artery and vein diameters measured by fluorescein angiography. Methods: Patients who had at least three anti-VEGF injections were included in the study. Patients were grouped (n: 72) regarding the intravitreal treatment as group 1 (Lucentis, n: 38) and group 2 (Avastin and /or Lucentis; n: 34). Fundus...

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PPV, Subretinal Injection of TPa and Intraocular Gas Tamponade for Thick Submacular Hemorrhage with ARMD

Advantages: To evaluate the safety and efficacy of pars plana vitrectomy, subretinal injection of tissue plasminogen activator (tPA) and intraocular gas tamponade for thick submacular hemorrhage caused by age-related macular degeneration. Methods: The authors reviewed the medical records of 16 consecutive patients who underwent pars plana vitrectomy, subretinal tPA (25ug/0.1ml) injection with 20% SF6 gas. The main outcome measures were...

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Submacular Surgery of High Pigment Epithelial Detachment in ARMD

Advantages: The purpose was to compare the effectiveness of intravitreal injection of ranibizumab and submacular surgery in patients with a subfoveal high pigment epithelial detachment (PED). Methods: The clinical trial included two groups of patients. Group 1 consisted of 11 patients (11 eyes), who received three initial intravitreal injections of ranibizumab. Group 2 consisted of 9 patients (9 eyes), who underwent intentional drainage...

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Expectant Attitude in Retinal Pigment Epithelium Detachment Associated to Hemochromatosis

F.J. Ascaso, P. Casas, C. Peiro, E. Nuñez, J. A. Cristóbal (Zaragoza, Spain) Advantages: Retinal pigment epithelium detachment (RPED) is a feature in many chorioretinal disorders. In other cases this condition occurs idiopathically. We report a case of idiopathic RPED in a patient with associated hemochromatosis. We decided to observe and not perform intravitreal antiangiogenic therapy because there was neither subretinal fluid nor a...

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Treatment of Submacular Hemorrhages from Macular Degeneration – One More Option

http://www.evrs.eu/medias/2010/congress/Hemorrhages.flv Ivan Tanev (Sofia, Bulgaria) Advantages: Sub-macular hemorrhage (SMH) is one of the most common complications of the neovascular age related macular degeneration (AMD). Eyes with large sub-retinal hemorrhages arising from exudative macular degeneration have a poor prognosis due to progressive fibrosis and organization of the sub-retinal clot.  Early removal of the sub-retinal blood...

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Anti-VEGF Monotherapy for Exudative ARMD Presenting with Concomitant Hemorrhages

http://www.evrs.eu/medias/2010/congress/Hemorrhages.flv Silvia Bopp, Andreas Schüler, Klaus Lucke (Bremen, Germany) Advantages:  To investigate the role of sub-retinal hemorrhages in exudative ARMD and investigate, if the hemorrhagic component influences the outcomes under continuous anti-VEGF therapy. Methods: Retrospective chart review of 30 patients presenting with exudative ARMD and concurrent sub-retinal hemorrhage of 2 disc...

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The Efficacy of Bevacizumab and Ranimizumab in Age-Related Macular Degeneration

Yong Sung You, Oh Kwon (Seoul, South Korea) Purpose: To compare the efficacy of Avastina and Lucentis in Neovascular AMD of Korean in South Korea. Materials and Methods: Retrospective, comparative study by reviewing the medical records of patients with wet AMD who were treated with anti-VEGF and followed up more than 6 months from January 2007 to November 2009. Results: 105 eyes (105 patients) were included. Avastin was injected in 32 eyes...

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Intravitreal Injection of Tissue Plasminogen Activator (TPA) and Gas C3F8 for the Management of Large Submacular Hemorrhage

Evangelia Papavasileiou, S. Liazos, Timothy Jackson (London, UK) Advantages: To describe the safety and efficacy of intravitreal TPA and C3F8 for the management of extensive sub macular hemorrhages (SMH), associated with AMD related choroidal neovascularisation (CNV) or Idiopathic Polypoidal Choroidal Vasculopathy (IPCV). Methods: Consecutive case series of 7 patients, presenting with acute SMH from neovascular AMD (N = 5) and IPCV (N =...

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Risk Factors for Recurrent Submacular Hemorrhage in Neovascular, Age-Related Macular Degeneration

June-Gone Kim, Sung Jae Yang, Jong Uk Hwang, Soo Geun Joe, Joo Yong Lee (Seoul, South Korea) Advantages: To describe the clinical characteristics and risk factors of recurrent, submacular hemorrhage in AMD. Methods: We reviewed the medical records of the neovascular AMD patients showing submacular hemorrhage at their onset. The required minimum follow-up period was 24 months, and any newly developed, submacular hemorrhage larger than one...

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Intravitreal Bevacizumab in Age-Related Macular Degeneration as a Rescue Therapy: Two-Year Results

Montserrat González-Sastre, Ignasi Jurgens, Rosa Sust-Ferrer (Barcelona, Spain) Purpose: To report the 2-year visual and anatomical outcomes in patients treated with intravitreal bevacizumab for neovascular age-related macular degeneration (AMD) in patients who failed after photodynamic therapy (PDT) or were not eligible to that treatment. Methods: Prospective, nonrandomized, open-label study of 114 eyes of 88 patients with AMD. We...

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Intravitreal Ranibizumab for Neovascular Age-Related Macular Degeneration

Ebru Demet Aygit, Çigdem Altan, Hülya Güngel (Istanbul, Turkey) Advantages: This study reports clinical outcomes of intravitreal Ranibizumab treatment for choroidal neovascularization (CNV) due to age-related macular degeneration (AMD) and to identify predictive factors that may influence visual acuity (VA) outcomes. Methods: Thirty-one patients (32 eyes) with CNV were followed up at least 6 months after intravitreal injection (0,5 mg)...

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Macular Translocation versus Autologous RPE and Choroid Transplantation for Exudative ARMD: Indications and Prognostic Factors

http://www.evrs.eu/medias/2010/congress/Age-Related-Macular-Degeneration-2.flv Barbara Parolini, Grazia Pertile (Verona, Italy) Advantages: Exudative AMD may benefit from different surgical approaches, when the standard of care is not successful. The efficacy of macular translocation or autologous RPE and choroid transplantation is linked to specific prognostic factors. The knowledge of the prognostic factors may guide the indications for...

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Full Macular Translocation for CNVM Secondary to ARMD, Not Responding to Anti-VEGFs

http://www.evrs.eu/medias/2010/congress/Age-Related-Macular-Degeneration-2.flv] Hassan Mortada (Cairo, Egypt) Advantages: Full macular translocation (FMT) has the advantages of complete removal of CNVMs not responding to repeated anti-VEGF intravitreal injections, reposition of the macular area over healthy retinal pigment epithelium and choriocapillaris and restoration of the normal macular configuration and function. Methods: The last...

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Epimacular Brachytherapy for Established Wet Age-Related Macular Degeneration: Interim Results

http://www.evrs.eu/medias/2010/congress/Age-Related-Macular-Degeneration-2.flv Timothy L. Jackson, Pravin Dugel, Robert Petrarca, Jeff Nau for the MERITAGE study group (London, UK) Advantages: Radiation has the potential to eliminate the proliferating endothelial cells, fibroblasts, and inflammatory cells that cause vision loss in wet age-related macular degeneration (AMD), and may therefore produce a more durable therapeutic effect than...

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PDT Low Fluence: Spectral Domain OCT

http://www.evrs.eu/medias/2010/congress/Age-Related-Macular-Degeneration-2.flv Guy L’Helgoual’ch (Brest, France) Advantages: Early evaluation with spectral domain OCT of the anatomical modifications of the various retinal layers after PDT, illustrates the need for adjuvant therapy. Methods: Standard parameters were used with respect to Visudyne dose, perfusion, wash out duration, and diode laser power setting. Low fluence was...

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Core Vitrectomy Using Intrector Combined with Bevacizumab in the Treatment of Choroidal Neovascularization in AMD

http://www.evrs.eu/medias/2010/congress/Age-Related-Macular-Degeneration-2.flv Slawomir Cisiecki (Lodz, Poland), Maciej Bednarski (Lodz, Poland), Michael Koss (Frankfurt am Main, Germany), Janusz Michalewski (Lodz, Poland) Advantages: The aim of combined treatment in cases of exudative ARMD is to reduce the rate of anti-VEGF injections. Core vitrectomy using intrector is indicated when there is no response after three monthly intravitreal...

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RPE Tears and Relation with Anti-VEGF Therapies

http://www.evrs.eu/medias/2010/congress/Age-Related-Macular-Degeneration.flv Sengul C. Ozdek, Sibel Eryigit, Berati Hasanreisoglu (Ankara, Turkey) Purpose: To document the incidence of RPE tears after anti-VEGF therapy. Methods: The reports of patients with wet ARMD treated with anti-VEGFs were reviewed for occurrence of RPE tears. Lesion type, the type of anti-VEGF used and prognosis after RPE tear were analyzed. Results: A total of 538...

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Tailored Avastin in Wet ARMD

http://www.evrs.eu/medias/2010/congress/Age-Related-Macular-Degeneration.flv Ivan Fiser, Frantisek Benda (Prague, Czech Republic) Advantages: Therapy with Avastin, fully tailored to the finding, can reduce the number of injections. The “saturation phase” of the traditional treatment scheme consisting of three monthly injections is not necessary in all cases. We always adapt the treatment to the course of the disease and keep the...

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Long-Term Clinicodiagnostic Correlations of CNV Treated with Bevacizumab on Demand

http://www.evrs.eu/medias/2010/congress/Age-Related-Macular-Degeneration.flv Janusz Michalewski, Slawomir Cisiecki, Krzysztof Dziegielewski, Zbigniew Pikulski, Dominik Odrobina, Jerzy Nawrocki (Lodz, Poland) Advantages: To describe and analyze morphological changes in the retina of patients treated on demand with intravitreal bevacizumab for more than 18 months. Methods: Patients with exudative AMD were treated when activity of CNV in...

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Management of Massive Suprachoroidal Hemorrhage after Intravitreal Bevacizumab Combined with Photodynamic Therapy in Neovascular, Age-Related Macular Degeneration

http://www.evrs.eu/medias/2010/videos/SooGeunJoe_VP6_768K.flv Soo Geun Joe, Jong Uk Hwang, Joo Yong Lee, June-Gone Kim (Seoul, South Korea) Advantages: The authors will discuss their successful management of massive suprachoroidal hemorrhage with secondary angle closure glaucoma, which developed after photodynamic therapy (PDT) combined with intravitreal bevacizumab injection (IVB) for age-related macular degeneration (ARMD). In this...

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Efficacy of Avastin Intravitreal Administration for Exudative

[fhttp://www.evrs.eu/medias/2010/congress/Age-Related-Macular-Degeneration.flv Ihor Novytskyy, Tetiana Smal, Markijan Novytskyy (Lviv, Ukraine) Advantages: Intravitreal administration of Avastin for exudative ARMD is cheap, effective and safe procedure. Methods: We have observed 147 patients (243 eyes) with wet ARMD, 68 females and 79 males, mean age 68 (52 to 87) years. 1 or 2 injections of Avastin were administered to 99 patients (168...

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Loading with Lucentis, Maintenance with Avastin: Can we Maintain the VA?

http://www.evrs.eu/medias/2010/congress/Age-Related-Macular-Degeneration.flv Sengul C. Ozdek, Sibel Eryigit, Berati Hasanreisoglu (Ankara, Turkey) Purpose: To determine if PRN Bevacizumab can maintain the visual acuity (VA) gained with loading Ranibizumab for wet ARMD. Methods: The reports of patients with wet ARMD treated with 3 monthly Ranibizumab followed by PRN Bevacizumab were reviewed retrospectively. VA and central foveal thickness...

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Three Year Results in Patients with Exudative Age-Related Macular Degeneration Using Constant Interval Dosing with Ranibizumab

http://www.evrs.eu/medias/2010/congress/Age-Related-Macular-Degeneration.flv Mark E. Hammer, W. Sanderson Grizzard, Ivan J. Suner (Tampa, FL, USA) Advantages: Unlike the patients in the HORIZON study who lost vision after 2 years when they were switched to PRN dosing, our patients maintained their vision over three years. The recurrence rate in the PrONTO trial was 91.9%. Since recurrences cause visual loss, prevention of recurrences by...

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Series of Three Ranibizumab Injections for the Treatment of Retrofoveolar Neovascular Age-Related Macular Degeneration, Two and a Half-Year Follow-Up

http://www.evrs.eu/medias/2010/congress/Age-Related-Macular-Degeneration.flv Corinne Gonzalez (Toulouse, France) Advantages: Effective, efficient – Good functional results with same or less injections than protocol studies – secure but less restrictive follow-up – less recurrences, – more retinal protective, – lastly cheaper. Methods: 92 eyes of 81 patients, 25 men, 56 women, with retrofoveolar...

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Treatment of Wet Age-Related Macular Degeneration – Avastin, the One and Only?!

http://www.evrs.eu/medias/2010/congress/Age-Related-Macular-Degeneration.flv Biljana Rascanin Draganic, Miroslav Vukosavljevic (Belgrade, Serbia) Advantages: Treating patients with wet AMD in a cost-effective way. Methods: 47 patients with wet AMD (diagnosed with fluorescein angiography-FA and optical coherent tomography-OCT) were given 3 monthly doses of 1.25 mg Avastin intravitreally, and were retreated as needed. All the patients were...

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Use of High Definition OCT in Assessing the Effectiveness of Ranibizumab Intravitreal Injections in Patients with Exudative Age-Related Macular Degeneration

http://www.evrs.eu/medias/2010/congress/Age-Related-Macular-Degeneration.flv Igor A. Malov, Sergey V. Nosov, N.S. Ponomaryova (Ekaterinburg, Russia) Advantages: Use of high definition OCT gives possibilities of better assessment of all retina layers after intravitreal Ranibizumab injections in patients with exudative Age-Related Macular Degeneration (ARMD). Methods: 10 eyes of 10 patients with wet ARMD were investigated. FAG confirmed...

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Spectral Domain OCT Determinants of Active Neovascular Membrane

http://www.evrs.eu/medias/2010/congress/Age-Related-Macular-Degeneration.flv Janusz Michalewski, Slawomir Cisiecki, Krzysztof Dziegielewski, Zbigniew Pikulski, Dominik Odrobina, Jerzy Nawrocki (Lodz, Poland) Advantages: To describe different signs of active CNV presented by Spectral domain OCT examination. Methods: Retrospective, descriptive analysis of patients treated “on demand” with repeated intravitreal injections of bevacizumab...

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Correlation between Morphologic Features on Spectral-Domain Optical Coherence Tomography and Autofluorescence in Patients with Neovascular Age-Related Macular Degeneration Treated with Intravitreal Ranibizumab

http://www.evrs.eu/medias/2010/congress/Age-Related-Macular-Degeneration.flv Evangelia Papavasileiou, S. Sivaprasad, S. Liazos, I. Vasiliadis (London, UK) Advantages: To assess the relationship of the pattern of fundus autofluorescence (FAF) with the size of the lesion, the type of neovascular complex, the macular retinal thickness and the integrity of the photoreceptor inner segment – outer segment (IS/OS) juction, or/and the...

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Sub-Classification of Exudative Age-Related Macular Degeneration Based on Anti-VEGF Response

http://www.evrs.eu/medias/2010/congress/Age-Related-Macular-Degeneration.flv Mark H. Nelson (Winston Salem, NC, USA) Advantages: A new classification for Exudative Age-Related Macular Degeneration (ARMD) is based on the clinical response to anti-VEGF medication. ICG video angiography reveals the choroidal nature of this pathological process and is used to predict the clinical response and create a strategy for sustainable vision...

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PPV in Acute Submacular Hemorrhage (Case Report)

Authors: Lidmila Prochazkova, Martina Zavorkova, Martin Hovorka, Usti Nad Labem, Czech Republic Advantages: To diminish the central scotoma and to improve the visual acuity. Methods: Two days after an acute subretinal hemorrhage, PPV with retinotomy, drainage and SF6 tamponade was performed. Effectiveness / Safety: Subjectively significant diminishing of the central scotoma and improving of the visual acuity from 2/50 to 5/50 was reached....

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Changes in Aqueous VEGF and PEDF after Ranibizumab Alone or Combined with Verteporfin for Exudative Age-Related Macular Degeneration

Authors: Jae Kyoun Ahn, Hyung Jin Moon, Yong Hwa Kim, South Korea Advantages / Purpose: To investigate changes in aqueous VEGF and PEDF in patients with subfoveal choroidal neovascularization (CNV) secondary to age-related macular degeneration (AMDCNV) after ranibizumab monotherapy or combining ranibizumab with photodynamic therapy (PDT). Methods: We recruited consecutive thirty-four patients with AMD-CNV and 10 controls. Baseline...

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To Combine or not to Combine Treatments in AMD: Is it a Matter of Savings ?

Authors: Begoña Pina Marín, José Juan Escobar Barranco, Manel Fernandez Bonet, Barcelona, Spain Advantages: The initial approach with combined therapies diminishes the need for retreatments without relinquishing gain of visual acuity (VA). This study compares two combined approach strategies to help to assess which one yields a greater VA gain, VA maintenance, OCT diminishing and rate of pretreatments. Methods: 36 patients have been...

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Temporal Peripheral Retinotomy for Evacuation of Submacular Hemorrhage Secondary to Arterial Macroaneurysm

http://www.evrs.eu/medias/2009/congress/Hemorrhages.flv Author: Hassan Mortada, Cairo, Egypt Advantages: Evacuation of submacular hemorrhage, secondary to arterial macroaneurysm, through a peripheral temporal retinotomy ensure rapid and complete removal of the submacular hemorrhage. This helps to prevent the toxic effect of the blood on photoreceptors with subsequent preservation of visual acuity. Experience from full macular translocation...

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Surgical Displacement of Medium-Sized Submacular Hemorrhage

http://www.evrs.eu/medias/2009/congress/Hemorrhages.flv Author: Sophie J. Bakri, Rochester, MN, USA Advantages: Surgical displacement of medium-sized thick submacular hemorrhage has the advantage of minimizing the toxic effects of blood on the retina. Methods: Pars plana vitrectomy, subretinal tPA and air-fluid exchange is performed. The patient lies flat on his back for 30 minutes, then upright for the next 24 hours. Effectiveness /...

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Submacular Hemorrhage: a Lost Eye?

http://www.evrs.eu/medias/2009/congress/Hemorrhages.flv Authors: Rossi Pietro, Claudia Castiglioni, Carlandrea Trillo, Genoa, Italy Submacular bleeding represents one of the worse end points in the evolution of age related degeneration. The aim of this investigation was to evaluate if displacement of the blood associated with anti-VEGF therapy or a RPE-choroid patch could yield a better functional outcome. Material and methods: 19 eyes of...

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Surgical Treatment of Submacular Hemorrhage

http://www.evrs.eu/medias/2009/congress/Hemorrhages.flv Authors: Grazia Pertile, Barbara Parolini, Verona, Italy Advantages: The treatment of submacular hemorrhage may benefit from different treatments on the bases of the hemorrhage’s area and location. Methods: Submacular hemorrhages located only under the retina and not under the retinal pigment epithelium (RPE) and involving an area within the arcades, were treated with intravitreal...

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An Atraumatic Method of Submacular Hemorrhage Management

http://www.evrs.eu/medias/2009/congress/Hemorrhages.flv Author: Aslanova Veronika, Odessa, Ukraine Advantages: Pneumatic displacement of SMH with intravitreal perfluoropropane without tPA allows clearing of the macular area from subretinal blood and achieves visual recovery in the short term. The procedure is atraumatic and cost-effective. Methods: Retrospective, noncomparative, interventional case series. The results of submacular...

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Macular Translocation with 360-Degree Retinotomy for the Managment of Retinal Pigment Epithelial Tear: 3 Years Results

http://www.evrs.eu/medias/2009/congress/Surgery.flv Authors: Barbara Parolini, Grazia Pertile, Verona, Italy To determine whether macular translocation with 360-degree retinotomy can stabilize and / or improve visual acuity in patients with retinal pigment epithelium (RPE) tear, given the increasing number of reports on this complication following vascular endothelial growth factor (VEGF)-modulating therapy. Methods: Prospective...

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Submacular Surgery for Myopic Choroidal Neovascular Membrane

http://www.evrs.eu/medias/2009/congress/Surgery.flv Author: Khaled El Rakhawy, Cairo, Egypt Advantages: In selected cases of myopic CNVM, surgical removal gives better visual outcome and relieves the patient from metamorphopsia as well as from the need to have many repeated injections with only limited improvement or merely stabilization of vision. Large membranes are particularly suitable for this approach. Methods: After complete...

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There Could Still Be a Place for Surgical CNV Removal

http://www.evrs.eu/medias/2009/congress/Surgery.flv Author: Klaus Lucke, Bremen, Germany Introduction: Surgical removal of subfoveal CNVs was practiced widely in the 1990s for the treatment of AMD and other exudative maculopathies. Since it virtually always left a large subfoveal RPE defect the visual results were by and large disappointing and the Submacular Surgery Trial (SST) showed that no statistically significant improvement in vision...

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Is Surgical Ablation of Blood Neovessels Still Useful?

http://www.evrs.eu/medias/2009/congress/Surgery.flv Author: Jean-Paul Amar, Cannes, France Subretinal surgery has slowly disappeared but 75% of eyes with a subretinal heamatoma are lost. The subretinal drainage of the blood and the surgical ablation of the blood neovessels seem to remain still useful with a quite low rate of complications.

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Epimacular Brachytherapy for Wet AMD: 24 Months Results

http://www.evrs.eu/medias/2009/congress/Surgery.flv Authors: TL Jackson, M Farah, JP Duprat, M Avila, GY Fujii, J Rossi, A Santos, R Palank , J Nau, London, UK Advantages: Epimacular brachytherapy (EMB) offers a novel, durable, costeffective treatment for age-related macular degeneration. Methods: Patients with classic, mixed or occult choroidal neovascularisation (CNV) underwent a pars plana vitrectomy followed by 24 Gy beta irradiation...

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Combined Treatment of Retinal Pigment Epithelium Serous Detachment in the Macular Region Caused by Age-Related Macular Degeneration

http://www.evrs.eu/medias/2009/congress/Surgery.flv Authors: Victor N. Kazaykin, Igor A. Malov, Yekaterinburg, Russia Advantages: Combination of laser retinopuncture and 25G endovitreal surgery provides a possibility to obtain attachment of retinal pigment epithelium serous detachment (RPE SD), caused by ARMD, in the macular region in its combination with posterior hyaloid detachment. Methods: After limiting retinal lasercoagulation at...

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Spectral OCT Determined Anti-VEGF Treatment

http://www.evrs.eu/medias/2009/congress/When-Re-Treating.flv Authors: Janusz Michalewski, Slawomir Cisiecki, Dominik Odrobina, Krzysztof Dziegielewski, Zbigniew Pikulski, Zofia Michalewska, Maciej Bednarski, Jerzy Nawrocki, Lodz, Poland Advantages: Spectral domain OCT determined anti- VEGF therapy enabled the reduction of number of injections. Moreover Spectral OCT enabled to determine some prognostic factors for anti- VEGF...

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Assessment of CNV Activity with a New Activity

http://www.evrs.eu/medias/2009/congress/When-Re-Treating.flv Authors: Sengul Ozdek, Cuneyt Ozmen, Berati Hasanreisoglu, Ankara, Turkey Advantages: A new activity scoring (AS) for assessment of the neovascular ARMD activity is defined. AS supplies standardization for the assessment of the lesion activity after anti-VEGF therapy. Methods: 52 eyes with neovascular ARMD treated with anti- VEGF agents were involved. The AS is based on 1) fluid...

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Classification for OCT Findings in CNV Secondary to AMD

http://www.evrs.eu/medias/2009/congress/When-Re-Treating.flv Author: Arwa Azmeh, Damascus, Syria Advantages: A classification of retinal and subretinal morphological changes based on OCT findings was suggested to be used in follow up of activity of CNV secondary to AMD after treatment, and for making the decision of retreatment. Methods: OCT scans through CNV secondary to AMD using Zeiss stratus OCT 3000 were analyzed. The OCT findings were...

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Definition and Management of Non-Responders to Anti-VEGF for CNV

http://www.evrs.eu/medias/2009/congress/When-Re-Treating.flv Authors: Sengul Ozdek, Cuneyt Ozmen, Berati Hasanreisoglu, Ankara, Turkey Advantages: To define the nonresponders of CNV to anti-VEGF treatment clearly so that unnecessary treatments with a costly agent can be prevented. Methods: A mini questionnaire with 7 items was send to the retina specialist in Turkey via e-mail. The questions were related with the definition of...

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One Year Study of Intravitreal Avastin and Combination with Avastin and Photodynamic Therapy in Neovascular Age Related Macular Degeneration

http://www.evrs.eu/medias/2009/congress/Combined-Treatments.flv Author: Taehyuk Koh, South Korea Advantages: To evaluate the one year outcome for monotherapy of avastin and combined therapy of avastin plus photodynamic therapy (PDT). Methods: Monotherapy group was received avastin 3 times every 6 weeks. In combination group, we started intravitreal avastin one week before and after PDT in the same way. In 49 eyes, we evaluated vision,...

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Analysis of Rate of Change in Macular Thickness in Combination Photodynamic Therapy and Bevacizumab Treatment for Exudative Age-Related Macular Degeneration (the VIA Study)

http://www.evrs.eu/medias/2009/congress/Combined-Treatments.flv Authors: Raimondo Forte, Naples, Italy; Michael J. Potter, Cheryl Claudio, Shelagh M. Szabo, Vancouver, Canada Advantages: To obtain a greater improvement after treatment of choroidal neovascularization (CNV) due to age-related macular degeneration (AMD). Methods: Prospective, randomized, double masked, controlled, interventional study. Thirty five eyes (35 patients) presenting...

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Triple Therapy for Exudative AMD

http://www.evrs.eu/medias/2009/congress/Combined-Treatments.flv Authors: Raimondo Forte, Paola Bonavolontà, Naples, Italy; Jean Paul Adenis, Pierre-Yves Robert, Limoges, France Advantages: To reduce the number of retreatments with intravitreal anti- VEGF in exudative age related macular degeneration (AMD). Methods: We evaluated all eyes with exudative AMD treated with bevacizumab or ranibizumab in monotherapy and in association with...

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Topical NSAID as Adjuvant Therapy after Ranibizumab Injection for CNV

Author : Sun Jin Lim, Seoul, South Korea After Ranibizumab injection intravitreally for treatment of CNV, Patients using topical NSAID eye drops showed a more gain in visual acuity and thinner central macular thickness (CMT). We retrospectively reviewed the medical record of patient with Lucentis injection from March 2007 to April 2008. Patients who received other treatment like Avastin injection or PDT were excluded. 35 eyes of 29...

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Randomized, Double Blind, Controlled Study with Verteporfin Photodynamic Therapy and Intravitreal Triamcinolone(IVTA) vs Triple Theraphy with Verteporfin Photodynamic Therapy, Intravitreal Triamcinolone and Intravitreal Ranibizumab in Patients with Subfoveal Choroidal Neovascularization (CNV) Secondary

http://www.evrs.eu/medias/2009/congress/Combined-Treatments.flv Authors: Rosa Maria Romero-Castro, Alfredo Morales, H. Quiroz-Mercado, Mexico Advantages: New modality treatmens are needed to increase effectiveness and reduce number of retreatmens in AMD patients. Triple therapy with PDT, intravitreal triamcinolone and intravitreal ranibizumab can be with less number of treatments and they’re for less cost a safe treatment option for...

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Tailored Anti VEGF for ARMD

http://www.evrs.eu/medias/2009/congress/Anti-VEGF-Alone.flv Author: Ron A. Adelman, New Haven, CT, USA Advantages: Reduction of number of injection, improving compliance Methods: Injection of anti VEGF monthly for 3 months. After three months decision for treatment is based on OCT. Effectiveness / Safety: Improved patient satisfaction.

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Tailored Anti-VEGF for ARMD

http://www.evrs.eu/medias/2009/congress/Anti-VEGF-Alone.flv Authors: Ivan Fiser, Frantisek Benda, Prague, Czech Republic Advantages: Tailored therapy with Avastin is an effective treatment of wet AMD. It can reduce the number of applications and save the patients´ money, thus enables more patients to be treated. There are potential super responders to Avastin in whom a single injection is a sufficient treatment. Methods: 274 eyes of 270...

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Combined Photodynamic Therapy with Intravitreal Bevacizumab for Neovascular ARMD

http://www.evrs.eu/medias/2008/congress/Combined-Photodynamic-Therapy-with-Intravitreal-Bevacizumab-for-Neovascular-ARMD.flv Young Ju Lew, Moon Jung Choi, Tae Gon Lee, Sung Won Cho, (Kim,’s Eye Hospital, Konyang Universtiy, Seoul, Korea ), Eun Jee Chung (NHIC, Ilsan Hospital, Gyunggido, Korea), Sung Woo Ha (Bungdang CHA General Hospital, Pochun CHA University, Guyunggido, Korea) Advantages: To investigate the efficacy of combined...

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Combined Bevacizumab and Photodynamic Theraphy in ARMD

http://www.evrs.eu/medias/2008/congress/Combined-Bevacizumab-and-Photodynamic-Theraphy-in-ARMD.flv V. Levent Karabaþ, Berna Özkan, Özgül Altýntaþ, Nurþen Yüksel, Yusuf Çaðlar Advantages: Combination of bevacizumab with PDT led to decreased need for recurrent injections of bevacizumab. Methods: The records of 62 patients who had combined bevacizumab injection and PDT for Age Related Macular Degeneration between March 2006 and...

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The New Method for Management of Long-Standing Exudative Retinal Detachment in ARMD Cases

Rodin Stanislav, Aslanova Veronika Advantages: The management of long-standing exudative retinal detachment in cases with ARMD with this technique allows to decrease significantly (almost halving) retinal thickness in posterior pole in short terms and is effective in visual recovery. Also, it is not expensive out-patient procedure. Methods: Intravitreal injection of C3F8 (0,6 ml) was performed under topical instillation anesthesia in...

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My Way of Assessment of Neovascular ARMD Avtivity

http://www.evrs.eu/medias/2008/congress/My-Way-of-Assessment-of-Neovascular-ARMD-Avtivity.flv Sengul Ozdek Advantages: In the era of anti-VEGF treatment of choroidal neovascular lesions (CNV) it is becoming more and more important to assess the activity of the lesion to decide for additional treatments. Here I present an activity scoring system which can easily be applied to all of the CNV lesions. Methods: I use 5 parameters to decide on...

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Intravitreal Use of Bevacizumab (Avastin) for Choroidal Neovascularization Associated with Age-Related Macular Degeneration: A Full-Field ERG Study

Masood Naseripour, Mohammad Reza Oladi, Khalil Ghasemi Falavarjani, Hossein Nazari Advantages: We describe the electrophysiologic changes in G-ERG recordings of subjects who were treated with 1.25 or 2.5 mg of intravitreal bevacizumab for treatment of CNV associated with AMD. Methods: In this prospective comparative interventional study, 23 patients with active choroidal neovascularization (CNV) associated with AMD were enrolled. Patients...

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Pneumatic Displacement of Acute Submacular Haemorrhage with and without the Use of Tissue Plasminogen Activator

Osman Cekic, Mehmet Cakir, Omer F. Yilmaz Advantages: To displace massive submacular haemorrhage by injecting intravitreal C3F8 gas with and without the use of tissue plasminogen activator (tPA). Methods: Twenty-one eyes of 21 patients with recently developed (up to 10 days) dense submacular haemorrhage underwent intravitreal injection of pure C3F8 gas (0.4-0.5ml) followed by face down positioning for pneumatic displacement. Seven of them...

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Atramatic Approach to Submacular Hemorrhage

http://www.evrs.eu/medias/2008/congress/Atramatic-Approach-to-Submacular-Hemorrhage.flv Silvia Bopp, Klaus Lucke (Augenklinik Universitaetsallee, Bremen, Germany) Advantages: To protect the fovea from severe toxic damage due to submacular hemorrhage and avoiding subretinal surgical manipulations. Methods: Indications for surgery are fresh subfoveal hemorrhages due to exudative macular degeneration (ARMD) or ruptured retinal arterial...

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3D-OCT Guided Photodynamic Therapy in Cases of Retinochoroidal Anastomoses

http://www.evrs.eu/medias/2008/congress/3D-OCT-Guided-Photodynamic-Therapy-in-Cases-of-Retinochoroidal-Anastomoses.flv Ioannis P. Theocharis Advantages: To avoid interventional diagnostic tests such as FA and ICG, using the point to point registration software of Topcons 3D OCT in cases where PDT is indicated, with ensuing benefit in terms of cost of treatment and avoidance of the risks of FA and ICG. Methods: Measurement of the treatment...

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Autologous Retinal Pigment Epithelium and Choroid Transplantation for Exudative ARMD with 180° Peripheral Retinotomy

http://www.evrs.eu/medias/2008/congress/Autologous-Retinal-Pigment-Epithelium-and-Choroid-Transplantation-for-Exudative-ARMD-with-180-Peripheral-Retinotomy.flv Grazia Pertile, Barbara Parolini Advantages: Autologous Retinal Pigment Epithelium (RPE) and choroid transplantation has a rationale in replacing the damaged RPE after surgical removal of a CNV and can be useful in order to restore better visual acuity. We present preliminary...

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AMD: Ten Years after Excision Surgery

http://www.evrs.eu/medias/2008/congress/AMD:-Ten-Years-after-Excision-Surgery.flv Christian Malbrel Advantages: How is the optical function ten years after surgical excision of sub retinal neovascularisation Methods: 125 patients were included Effectiveness / Safety: Analysis of useful macular sensitivity, color vision perception, and remaining visual pigment was...

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Macular Translocation in the Age of Anti VEGF

http://www.evrs.eu/medias/2008/congress/Macular-Translocation-in-the-Age-of-Anti-VEGF.flv Gabor B. Scharioth Advantages: In case of wet AMD with large subretinal hemorrhage, fresh RPE rip or non responding to anti-VEGF therapy we are convinced that macular translocation is the last chance for single eyed patients to preserve useful vision. Still today this approach is the only way to bring the fovea onto healthier RPE. Methods: Pars plana...

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Tailored Therapy with Avastin Helps Patients with AMD to Save Money

http://www.evrs.eu/medias/2008/congress/Tailored-Therapy-with-Avastin-Helps-Patients-with-AMD-to-Save-Money.flv Ivan Fiser, Nikola Toskova, Cornea Lexum Eye Clinic, Prague, Czech Republic Advantages: For senior patients even the cheapest therapy with three monthly injections of Avastin, followed with three-month check-ups, can exceed their financial limits. The tailored therapy, based on the application of a single injection, followed by a...

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New Vessels Session

http://www.evrs.eu/medias/2007/videos/newvessels.flv

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Tritherapy Using Avastin, Visudyne and Triamcinolone as Treatment of Neovascular AMD

Guy l’Helgoualch, MD (Brest, France) PURPOSE: To check using Avastin in intravitreous injection reduces the surface and the thickness of the neovascular membrane. To check improving the effect of PDT and reducing the side effects increases the final visual acuity. To verify this protocol of tritherapy reduces the number of treatment during the period of follow-up. METHODS: The population of patients includes the same proportion of...

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Treatment of Macular Hematoma Due to Age-related Macular Degeneration by Displacement with Vitrectomy and Gas Injection

Jean-François Le Rouic, MD (Nantes, France), Frank J. Becquet, MD, PhD (Nantes, France), Pascal Peronnet, MD (Nantes, France), Caroline Pousset-Decre, MD (Nantes, France), Elisabeth Hermouet- Leclair, (Nantes, France), Philippe Gayet, (Nantes, France), Didier Ducournau, MD (Nantes, France) PURPOSE: To report the pre- and postoperative findings after displacement of recent submacular hemorrhages due to age-related macular degeneration...

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Large Case Series of Different Types of CNV after Combination Treatment (PDT with Intravitreal Triamcinolone)

Albert J. Augustin, MD (Sulzfeld, Germany), Indre Offermann, MD (Karlsruhe, Germany), Stephan Puls, MD (Karlsruhe, Germany), Frank H.J. Koch, MD (Frankfurt am Main, Germany), Ursula Schmidt-Erfurth, MD (Vienna, Austria)* PURPOSE: To assess the treatment and outcome of patients with CNV treated with PDT combined with intravitreal triamcinolone (TA). METHODS: Patients (n? 307) suffering from CNV (76.2% subfoveal, 12.1% juxtafoveal, 11.7%...

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Combination Therapy of Photodynamic Therapy with Verteporfin and Intravitreal Pegaptanib in the Management of Exudative ARMD

Asheesh Tewari, MD (St. Louis, MO), Rajendra S. Apte, MD, PhD (St. Louis, MO)* PURPOSE: To examine outcomes of a group of previously treatment naïve patients treated with combined photodynamic therapy with verteporfin and intravitreal pegaptanib for choroidal neovascularization secondary to ARMD. METHODS: Retrospective review of ten eyes of ten consecutive patients with CNV secondary to ARMD. These patients had  not received  any prior...

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Six-month Results of a Randomized, Double-masked, Controlled Trial of Intravitreal Triamcinolone as an Adjunct to Photodynamic Therapy in Predominantly Classic Neovascular Age-related Macular Degeneration: The Canadian RETINA Study

http://www.evrs.eu/medias/2006/congress/Six-month-Results-of-a-Randomized,-Double-masked,-Controlled-Trial-of-Intravitreal-Triamcinolone-as-an-Adjunct-to-Photodynamic-Therapy-in-Predominantly-Classic-Neovascular-Age-related-Macular-Degeneration:-The-Canadian-RETINA-Study.swf David Maberley, MD, FRCSC, MSc (Vancouver, Canada),* PURPOSE: To compare safety data and ETDRS visual acuity outcomes data for one-hundred subjects with predominantly...

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