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Detection of choroidal neovascularization using Optical Coherence Tomography Angiography compared to Traditional Angiography in Exudative Age-Related Macular Degeneration

SCIENTIFIC POSTER 2016_Detection of choroidal neovascularization using Optical Coherence Tomography Angiography compared to Traditional Angiography in Exudative Age-Related Macular Degeneration Purpose: To determine the sensitivity and specificity of optical coherence tomography angiography (OCTA) in detecting choroidal neovasculararization (CNV) compared to fluorescein angiography (FA) considered as the first choice technique. Methods: A...

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Comparison of the Effect of Ranibizumab and Aflibercept for Choroidal Thickness Changes in Wet AMD

SCIENTIFIC POSTER 2016_Comparison of the Effect of Ranibizumab and Aflibercept for Choroidal Thickness Changes in Wet AMD Hee Seong Yoon Purpose: To compare the changes in subfoveal choroidal thickness (SFCT) after intravitreal ranibizumab or aflibercept injections for neovascular age-related macular degeneration (nAMD). Methods: Medical records of 67 treatment-naive patients (69 eyes) who were diagnosed with neovascular AMD (nAMD) and...

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Choroidal Neovascular Membrane in Children

SCIENTIFIC POSTER 2016_Choroidal Neovascular Membrane in Children Maha M. Elshafei Case 1: A case of seven-year-old girl who presented to the eye clinic complaining of decreased vision in both eyes. Examination showed bilateral active choroidal neovascular membrane in the macular area, which was, treated with multiple intravitreal injections of Ranibizumab. Screening of the family showed bilateral Vitilliform maculopathy in the younger...

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Response of Pigment Epithelial Detachment to Anti-VEGF Treatment in AMD

SCIENTIFIC POSTER 2016_Response of Pigment Epithelial Detachment to Anti-VEGF Treatment in AMD Han Joo Cho Objective: To evaluate the therapeutic response of pigment epithelial detachment (PED) to anti-vascular endothelial growth factor (VEGF) treatment in neovascular age-related macular degeneration (nAMD), and identify predictive factors for PED resolution after treatment. Methods: A total of 202 treatment-naive nAMD eyes presenting PED...

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Results of Intravitreal Aflibercept in Insufficient Responders to Prior Anti-VEGF Therapy in Neovascular AMD

SCIENTIFIC POSTER 2016_Results of Intravitreal Aflibercept in Insufficient Responders to Prior Anti-VEGF Therapy in Neovascular AMD Zeynep Alkin Purpose: To report the outcomes of intravitreal aflibercept therapy in eyes with refractory neovascular age-related macular degeneration (AMD) switched from intravitreal bevacizumab or ranibizumab. Methods: This is a retrospective review of eyes with neovascular AMD switched to intravitreal...

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Short-term Safety Profile of Intravitreal Ziv-aflibercept

Aim: To evaluate the safety of intravitreal ziv-aflibercept (Zaltrap®) in the treatment choroidal neovascularization (CNV) secondary to age-related macular degeneration (AMD). Methods: Eligible eyes with CNV secondary to AMD each received a single intravitreal injection of ziv-aflibercept. Comprehensive ophthalmic examinations and detailed systemic evaluations were performed at baseline, and days 1, 7, and 30 after injection, and...

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Effectiveness of Low-energy Light Irradiation for Exudative AMD After Anti-VEGF Therapy

Studied the effectiveness of low-energy light irradiation in patients with exudative form of age-related macular degeneration after anti-VEGF therapy. The main group included 62 patients (the 69 eyes), who received two courses of low-energy light radiation within 6 months after the anti-VEGF therapy. A control group of 41 patients (44 eyes) to the monitoring took place only anti-VEGF therapy. The total period of observation was 1 year....

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Eylea in the Treatment of Wet AMD : Comparison of Different Treating Regimens

Advantages: We compared different regimens of aflibercept (EYLEA) injections in patients with wet AMD. Methods: We analyzed 195 eyes of 186 patients with wet AMD, treated between 2013 and 2015 with aflibercept. We assessed BCVA and central retinal thickness and compared these parameters in four subgroups of patients treated using four different regimens: Only three monthly loading doses. Three loading doses followed with individual...

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Individualized Anti-VEGF Treatment Approach for Neovascular AMD

Aim: To describe the individualized treatment schedule for each neovascular ARMD patient combining PRN and proactive treatment approach. Methods: There are different treatment approaches considering the anti-VEGF treatment for neovascular ARMD. These are monthly treatment, fixed dose with more than monthly intervals or individualized treatments which can be either PRN or treat & extend or wait & extend or observe & plan...

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Wet AMD After Vitrectomy for RD

Presentation shows two cases of choroidal neovascularisation after vitrectomy. Both cases undergo two surgical procedures. In first case the second procedure was performed to remove epiretinal membrane which causes macular edema. Second case was PVR detachment surgery treated in two operations. In first procedure we attached retina with silicone oil tamponade and 180 degrees retinectomy, and in second one we peel membranes and remove...

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Monthly Alternating Injections of Aflibercept and Bevacizumab for Wet AMD

June Gone Kim_SCIENTIFIC POSTER 2015 Purpose: Every 2-months after 3 initial monthly doses had been used as a standard regimen of intravitreal aflibercept for the treatment of wet AMD. In clinical practice, however, bimonthly aflibercept is insufficient for the maintenance in some cases. This study was designed to investigate the efficacy of monthly alternating injections of aflibercept and bevacizumab for maintenance treatment of wet...

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Refractory Subfoveal Subretinal Fluid in Neovascular ARMD: Is There a Protective Effect on Good Visual Acuity?

Purpose: To investigate the functional outcome of eyes with neovascular age-related macular degeneration (nAMD) treated with ranibizumab which retain good visual acuity despite chronic, persistent subretinal fluid (SRF). Methods: This retrospective, interventional case series included 12 eyes of 11 patients with nAMD which have (mean age, 70.2 years; range, 58 to 78 years) persistent SRF despite anti-VEGF therapy, and good long-term visual...

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Problems of Anti-VEGF Therapy in Massive Subretinal Hemorrhage in Wet AMD

Actuality: In most cases, the period and the gradual reduction of visual acuity in AMD allows patients to adapt to low vision without a sudden loss of central vision and independence. In case of a massive subretinal hemorrhage on the basis of AMD, patients experience sudden loss of central vision and the associated debasement in the quality of life. A-VEGF therapy in the treatment of subretinal hemorrhage, appears ambiguous. Changes in...

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Six Months Results of Aflibercept versus Ranibizumab for Treatment of Wet-AMD

Oh Jae Kim_SCIENTIFIC POSTER 2015 Purpose: To compare the six-month clinical results of ranibizumab with aflibercept for the treatment of wet age-related macular degeneration (wet-AMD). Methods: Medical records of 44 eyes of 44 patients who underwent intravitreal ranibizumab (0.5mg / 0.05ml) or aflibercept (2.0mg / 0.05ml) injection for wet-AMD with more than 6 months of follow-up were reviewed retrospectively. All patients were treated...

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Idiopathic Choroidal Neovascular Membrane in a 9 Years Old Child

Veronica Ramos Camara_SCIENTIFIC POSTER 2015 An 8-years-old boy was referred to our service for evaluation of decreasing vision in his right eye. Personal Background: Patent ductus arteriosus surgery. His family denied history of trauma or inflammation. His best corrected visual acuity in his right eye was light perception and 20/20 in his left eye. Retinography showed subfoveal choroidal neovascular membrane (CNVM) with subretinal...

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An Unusual Case of CNVM with Subretinal Pigment Epithelial Hemorrhage in a Proved Case of Light Chain Disease with Kidney Failure

Sufiyan Shaikh_SCIENTIFIC POSTER 2015 We report a case of CNVM with RPE degenerative changes with sub RPE detachments in biopsy proven light chain nephropathy in a 33 year old female. A fundus change over a period of 3 years was monitored from the initial vis it. The patient underwent best corrected visual acuity (BCVA), fundus photography and ultrasound in the right eye during the initial visit of presentation. In the follow up visit after...

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TTT-like Laser Coagulation of Peripapillary Neovascular Membranes

Media not available due to technical recording problems. EVRS is very sorry for the inconvenience.   In eyes with AMD or other choroidal pathologies prone to develop subretinal neovascular membranes we occasionally encounter cases where the CNV is localized around the optic disc, giving rise to an exudative retinal detachment frequently involving the macula and reducing visual function. When the CNV does not involve the foveal zone...

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Gloucestershire Model for Treating Neovascular ARMD – An Industrial Production Line!

Media not available due to technical recording problems. EVRS is very sorry for the inconvenience.   The management of patients with neovascular age related macular degeneration (nAMD) forms a large and increasing proportion of hospital eye service activity worldwide, particularly since the introduction of intravitreal anti-VEGF therapy. The delivery of anti-VEGF therapy has created substantial service pressures on ophthalmology...

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Personalized Medicine Applied to AMD

Media not available due to technical recording problems. EVRS is very sorry for the inconvenience.   Introduction: AMD is a multi factorial disease triggered by aging (parainflammation), and genetic, cardio-vascular, inflammatory and environmental factors. The natural history of the disease shows that 80% of neovascular membranes are occult and that their natural course is a succession of relapse and remission phases. Patients and...

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Reasons for Aflibercept Prescription in Wet AMD in Real Life

Media not available due to technical recording problems. EVRS is very sorry for the inconvenience.   Purpose: To describe the main reason for aflibercept prescription in the treatment of exudative age-related macular degeneration (AMD) during the initial weeks of availability of this drug in a clinical setting. Patients and methods: During the first 16 weeks of availability in France, four experienced practitioners in retinal disease...

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Epiretinal Membranes in Neovascular Age-related Macular Degeneration: Effect on Outcomes of Anti-VEGF Therapy

Media not available due to technical recording problems. EVRS is very sorry for the inconvenience.   Introduction: Vitreomacular interface changes of AMD patients such as posterior vitreous detachment (PVD), vitreomacular adhesion (VMA) and vitreomacular traction (VMT) have been addressed in several clinical studies using optic coherence tomography (OCT).However role of epiretinal membrane (ERM) has not been investigated in the concept...

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Primary Combination Therapy for Exudative ARMD

Media not available due to technical recording problems. EVRS is very sorry for the inconvenience.   Objective: Efficacy of Primary ICG-directed PDT Triple Therapy with verteporfin (Visudyne), ranibizumab (Lucentis), and triamcinolone acetonide (Triescence) versus €˜Standard of Care, i.e. anti-VEGF monotherapy, for the treatment of Exudative ARMD. Design: Retrospective, non-randomized, exploratory study. Methods: 2 year study of 115...

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Structural Changes of Choroidal Neovascularization in Indocyanine Green Angiography After Ranibizumab Injection

SCIENTIFIC POSTER_Il Han Yun Purpose: To investigate the mechanism of choroidal neovascularization (CNV) recurrence followed by intravitreal ranibizumab injections based on vascular structural changes of choroidal neovascularization (CNV) using indocyanine green angiography (ICGA) Methods: A total of 31 patients with exudative age-related macular degeneration and CNV whose structures were identifiable in ICGA. Patients with either...

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Morphology of PED as a Predicting Factor of Outcomes for Anti-VEGF Therapy of Wet AMD

SCIENTIFIC POSTER_Elena Kozina OCT-criteria for a potential risk of pigment epithelium (PE) tear development, PE reattaching and PED resistance at A-VEGF therapy of patients with wet AMD, accompanied by high PE detachment are determined retrosprctively for predicting the possible treatment outcome and determination of the optimal mode of A-VEGF injection. General Considerations: In clinical practice the different morphological forms of...

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Two Different Options in the Treatment of Premacular Hemorrhage Secondary to Macroaneurysm

  SCIENTIFIC POSTER_Ines Coutinho Purpose: Premacular hemorrhage is one major cause of sudden visual loss and occurs in a variety of disorders, among others in retinal arterial macroaneurysms (RAM). Possible therapeutic options include observation, vitrectomy, intravitreal rT-PA injection or laser posterior hyaloidotomy. However, the best treatment is still controversial. We report on 2 cases with premacular haemorrhage due to RAM. The...

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Cine-angiography ICG Demonstrates Choroidal Re-perfusions After Vortex Vein Occlusions in AMD

Choroidal volume is reduced along aging. Choroidal perfusion is decreased by 37% in AMD (Grunwald JE1998) (1) Choroidal thickness is reduced by 50% (EDI-OCT study-Spaide RF 2009) (2) Vortex Veins Occlusion (VVO) might restaure choriocapillaris perfusion. (Hayreh SS 1982, experiments in the Rhesus monkey) (3) and (Bonnet M 1985, surgery in 17 human eyes with AMD) (4). The goal of the study was to evaluate the choroidal perfusion after...

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Intravitreal Procrit in Eyes with Geographic Atrophy Secondary to ARMD

Media not available due to technical recording problems. EVRS is very sorry for the inconvenience.   Purpose: To investigate the role of Procrit intravitreal injections in stabilizing vision and geographic atrophy (GA) in eyes with atrophic AMD and to characterize SD-OCT and central visual field acuity perimetry (Omnifield) findings associated with GA. Methods: A retrospective pilot study examined eyes treated off-label with Procrit...

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Cine-angiography ICG Demonstrates Choroidal Re-perfusions After Vortex Vein Occlusions in AMD

Media not available due to technical recording problems. EVRS is very sorry for the inconvenience.   Choroidal volume decreases with age. Choroidal perfusion is also decreased by 37% (Grunwald JE1998)- 50% (EDI-OCT study-Spaide RF 2009) in AMD. Vortex Veins Occlusion (VVO) might restore choriocapillaris perfusion. (Hayreh SS 1982, experiments in the Rhesus monkey, Bonnet M 1985, surgery in 17 human eyes with AMD). The goal of the study...

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The Arrest of Dry AMD Development by Means of LED-based Low-light Therapy. The Dynamic of Acuity and Macular Pigment Optical Density

Advantages: To arrest the dry AMD development the original low-light therapy during two sessions in the course of year was used. Methods: To apply the low-light therapy the Vision Aid Mark-III prototype was used to illuminate retina by three different wavelengths of light. To evaluate the optical density of the macular pigment, the MacuLux® Praxis (Ebiga VISION GmbH, Germany) was used. Effectiveness: The main group consist of 90...

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Expression Pattern of Extracellular Matrix Components After Ranibizumab for Neovascular ARMD

Poster Malgorzata Nita Purpose: The aim of the study was to evaluate the effect of loading doses of ranibizumab on gene expression of matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs) in patients with CNV/AMD. Setting: Study was conducted by the Department of Ophthalmology, Medical University of Silesia, Independent Public Clinical Hospital, Katowice, Poland. Methods Inclusion criteria: patients ≥60...

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Ocular Adverse Events Related to Intravitreal Ranibizumab in Patients with Exudative ARMD

Purpose: Anti-VEGF injections have been standard treatment of exudative age-related macular degeneration (ARMD) in recent years. However multiple and recurrent injections needed to maintain the efficacy of the treatment may lead to adverse side effects related to this regimen. The aim of this study was to find out ocular adverse events associated with intravitreal injection of ranibizumab for the treatment of exudative ARMD performed in a...

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Retinal Nerve Fiber Layer Thickness Change in Wet AMD Treated with Ranibizumab

Poster Ozen Ayranci Osmanbasoglu Advantages: To assess the effect of intravitreal (IV) ranibizumab therapy on retinal nerve fiber layer (RNFL) thickness. Methods: Fourteen eyes of 11 treatment naive patients with neovascular age related macular degeneration treated with ranibizumab were included. Patients were followed up by monthly examinations and IV ranibizumab injections were done as on needed basis. RNFL thickness s was measured by...

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Morphological Changes in Spectral Domain Optical Coherence Tomography Guided Bevacizumab Injections in Wet AMD, 12-months Results

Advantage: This paper aims to describe retinal changes during Spectral Domain Optical Coherence Tomography (SD-OCT) guided Bevacizumab treatment for neovascular age- related macular degeneration (AMD). Material and Methods: 47 eyes of 45 patients with wet AMD treated on demand with Bevacizumab. We used 3-dimensional SD-OCT to measure photoreceptor defects and subretinal fibrosis. The main efficacy endpoints were the SD-OCT measurements...

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Early Onset Exudative AMD Detected with Monthly SD-OCT with Eye-tracking of the Fellow Eye in Patients Treated with Anti-VEGF

Advantage: To determine the frequency and characteristic features of new- onset neovascularization (CNV) in age related macular degeneration (AMD) with spectral domain optical coherence tomography (SD-OCT). Methods: Prospective, observational study of 68 patients with unilateral CNV treated with Bevacizumab. SD-OCT and visual acuity (logMAR) was measured at baseline and then monthly in both, the Bevacizumab treated eye and in the study...

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Ranibizumab vs Bevacizumab vs Combined Therapy PDT-Ranibizumab for the Treatment of Age-related Macular Degeneration: One-year Follow-up

Advantages: To compare the efficiency of three different treatments analyzing the changes in visual acuity (VA), number of used doses and costs. Methods: In a randomized prospective study we created three groups: Group-A, where we administered 0.5 mg (0.05ml) of intravitreal (IV) Ranibizumab, for three consecutive months; Group-B, where we combined the photodynamic therapy together with an IV injection of Ranibizumab; Group-C, where we...

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Combined Intravitreal Anti-VEGF & Subtenon Corticosteroids in AMD to Reduce ME Recurrence

Purpose:  To evaluate combined treatment of Anti-VEGF & subtenon corticosteroids for recurrent macular edema (ME) associated to choroidal neovascularization (CNV) due to age related macular degeneration (AMD). Material & Methods: Cases of CNV in AMD were included in this retrospective study. All types of CNV could be included (classic, minimally classic, occult, PEDs) Results: This combined therapy seemed to decrease ME...

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Pedunculated choroidal – RPE Patch Transplantation in Severe Neovascular Macular Degeneration

Advantages: To perform an autologous RPE graft in a case of fibrotic CNV leaving a link between the patch and the original site of it. Methods: Standard vitrectomy with induction of retinal detachment and retinectomy of the 180° temporal retina; removal of fibrotic subfoveal fibrotic membrane, preparation of a choroidal patch to move on the macular area leaving a part connected with the original site of choroid. Effectiveness / Safety:...

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Tachyphylaxis During Ranibizumab Treatment of Exudative Age-related Macular Degeneration

Purpose: To determine the rate of tachyphylaxis during Ranibizumab therapy for exudative age-related macular degeneration (AMD). Methods: The records of patients treated with Ranibizumab were retrospectively reviewed. Tachyphylaxis was defined as an initial good response to Ranibizumab followed by a decrease or absence of the response to Ranibizumab despite a minimum of two injections du ring follow-up in patients with exudative...

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Surgical Approach to Massive Subretinal Hemorrhages Secondary to Neovascular ARMD

Purpose: Different surgical management of massive subretinal hemorrhage secondary to ARMD will be defined. Methods: Pars plana vitrectomy (PPV) with 360 retinotomy and removal of subretinal hemorrhage and membrane +/- choroidal patch graft is performed to 3 cases of massive subretinal hemorrhage secondary to ARMD and the results and surgical videos will be presented. Take home message: Subretinal surgery is unavoidable in such cases to...

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Individualized Approach to Neovascular ARMD Treatment

Purpose: To define a new approach for treatment of neovascular ARMD cases with less frequent visits and injections. Methods: Neovascular ARMD cases that have been followed-up for 1-2 year period were analyzed retrospectively and those who had regular intervals of recurrence were identified. An individualized visit and injection period was defined for each of those patients separately. Effectiveness: Those cases that had regular...

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CNV in AMD

Autologous RPE and choroid transplantation for the treatment of CNV in AMD will be presented in details.

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PPV with Choroid-RPE Patch Graft for Massive Hemorrhage Due to Neovascular ARMD

This is a video of a patient with age related macular degeneration who had a macular scar in his right eye and a new subretinal massive hemorrhage causing hemorrhagic retinal detachment in his left eye which used to be his better eye. A cataract surgery combined with pars plana vitrectomy with 360 retinotomy, removal of subretinal hemorrhage, clots and choroidal neovascular membrane, and choroid-retina pigment epithelial patch graft was...

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Removing the Submacular Scar

Submacular scar in long standing age related macular degeneration cases severly compromise the vision and vis a vis the day to day activity of the person thus affected. Minimum improvements in the vision make these patients happier. It helps them with at least the benefit of improved field of vision. Here we describe surgery in a patient with long standing macular scar. Novel instrumentation technique was used to make a sub macular cannula....

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Autologous Transplantation of RPE & Choroid for Wet AMD: Functional Results and Prognostic Factors After a Long-term Follow-up

Advantages: Choroidal neovascularization in age related macular degeneration (AMD), non-responder to standard care, might be treated with autologous transplantation of retinal pigment epithelium and choroid (PATCH). The purpose was to define prognostic criteria for this surgery, to improve the result. Methods: Thirty eyes underwent PATCH surgery. Follow-up was 36 months. Patients received ETDRS, OCT scan and fluorescein and indocyanine...

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Do Neovascular AMD Lesions Associated with PED Behave Differently to Anti-VEGF Treatment?

Purpose: To document the prognosis of eyes with neovascular AMD associated with any pigment epithelial detachment (PED) during the course of anti VEGF treatment. Methods: The medical records of 331 eyes with neovascular AMD treated with intravitreal anti VEGFs were retrospectively errate for the presence of PED. The visual and anatomical (OCT) prognosis of the cases and complication rates after treatment were determined. Results: PED was...

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Proteomics in Exudative AMD

Purpose: To errate and compare vitreous samples of exudative AMD with these of floater patients with PROTEOMICS. Methods: Twenty-three vitreous samples (15 AMD and 8 controls) from patients undergoing 23 gauge single-site core vitrectomy for combined intravitreal treatment were errate with capillary electrophoresis coupled to mass spectrometry. Results: A total of 5949 polypeptides (PP) could be defined in all samples based on mass,...

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Combined Treatment with Sub-tenon Injection of Triamcinolone and Intravitreal Anti-VEGF Injection in Refractory Neovascular ARMD

Advantages: Combined treatment with sub-Tenon’s injection of triamcinolone and intravitreal anti-VEGF injection has beneficial effect in improving visual acuity and anatomic outcomes in refractory neovascular AMD patients. Methods: Seven eyes of 7 patients with refractory neovascular age-related macular degeneration (AMD) secondary to polypoidal choroidal vasculopathy (PCV) were enrolled. Refractory PCV was defined as no response of...

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Relationship of Elevated Osteoprotegerin with Exudative ARMD

Purpose: The aim of the present study was to elucidate if there is any relationship between osteoprotegerin (OPG) and exudative age-related macular degeneration (E-AMD), a disease with similar risk factors as coronary artery disease. Methods: In a cross-sectional study, we compared 45 E-AMD patients with 45 matched controls. Diagnosis was confirmed by fluorescein angiography. Serum samples were analyzed for OPG, RANK Ligand, low-density...

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The Effect of Anti-VEGF Treatment on Fundus Fluorescein Angiographic Findings in AMD Cases

Advantages: To analyse the effect of anti-VEGF treatment on arm to retinal circulation, capillary time, venous filling time, retinal artery and vein diameters measured by fluorescein angiography. Methods: Patients who had at least three anti-VEGF injections were included in the study. Patients were grouped (n: 72) regarding the intravitreal treatment as group 1 (Lucentis, n: 38) and group 2 (Avastin and /or Lucentis; n: 34). Fundus...

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PPV, Subretinal Injection of TPa and Intraocular Gas Tamponade for Thick Submacular Hemorrhage with ARMD

Advantages: To evaluate the safety and efficacy of pars plana vitrectomy, subretinal injection of tissue plasminogen activator (tPA) and intraocular gas tamponade for thick submacular hemorrhage caused by age-related macular degeneration. Methods: The authors reviewed the medical records of 16 consecutive patients who underwent pars plana vitrectomy, subretinal tPA (25ug/0.1ml) injection with 20% SF6 gas. The main outcome measures were...

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Submacular Surgery of High Pigment Epithelial Detachment in ARMD

Advantages: The purpose was to compare the effectiveness of intravitreal injection of ranibizumab and submacular surgery in patients with a subfoveal high pigment epithelial detachment (PED). Methods: The clinical trial included two groups of patients. Group 1 consisted of 11 patients (11 eyes), who received three initial intravitreal injections of ranibizumab. Group 2 consisted of 9 patients (9 eyes), who underwent intentional drainage...

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Comparison of the Incidence of Cardiovascular Morbidity in Patients Without and with Age-related Macular Degeneration

M Kowalska, J Ciszewska, K Wajs, D Kêcik (Warsaw, Poland) Advantages: The purpose of the study was to evaluate the incidence of cardiovascular diseases and risk factors in patients with dry and wet AMD. The control group consisted of patients with normal maculas. Methods: 242 patients: 156 pts with established diagnosis of AMD and a mean age of 70.8 +/- 12.1 years and 86 pts with normal appearing maculas and a mean age 69.8 +/- 7.2 years...

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Expectant Attitude in Retinal Pigment Epithelium Detachment Associated to Hemochromatosis

F.J. Ascaso, P. Casas, C. Peiro, E. Nuñez, J. A. Cristóbal (Zaragoza, Spain) Advantages: Retinal pigment epithelium detachment (RPED) is a feature in many chorioretinal disorders. In other cases this condition occurs idiopathically. We report a case of idiopathic RPED in a patient with associated hemochromatosis. We decided to observe and not perform intravitreal antiangiogenic therapy because there was neither subretinal fluid nor a...

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Intravitreal Procrit in Eyes with Geographic Atrophy Secondary to ARMD

C Majcher (Salus), SH Sinclair (Drexel Univ School Med), W Li (Drexel Univ School Med), P Presti (Georgia Institute of Technology, Atlanta) Objective: Investigate erythropoietin intravitreal injections stabilization of central discriminant visual fields (CDVF) and GA progression in atrophic ARMD and correlate OCT findings with CDVF and patterns of GA progression. Methods: Retrospective pilot study of patients with GA AMD with fovea...

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Treatment of Submacular Hemorrhages from Macular Degeneration – One More Option

http://www.evrs.eu/medias/2010/congress/Hemorrhages.flv Ivan Tanev (Sofia, Bulgaria) Advantages: Sub-macular hemorrhage (SMH) is one of the most common complications of the neovascular age related macular degeneration (AMD). Eyes with large sub-retinal hemorrhages arising from exudative macular degeneration have a poor prognosis due to progressive fibrosis and organization of the sub-retinal clot.  Early removal of the sub-retinal blood...

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Anti-VEGF Monotherapy for Exudative ARMD Presenting with Concomitant Hemorrhages

http://www.evrs.eu/medias/2010/congress/Hemorrhages.flv Silvia Bopp, Andreas Schüler, Klaus Lucke (Bremen, Germany) Advantages:  To investigate the role of sub-retinal hemorrhages in exudative ARMD and investigate, if the hemorrhagic component influences the outcomes under continuous anti-VEGF therapy. Methods: Retrospective chart review of 30 patients presenting with exudative ARMD and concurrent sub-retinal hemorrhage of 2 disc...

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The Efficacy of Bevacizumab and Ranimizumab in Age-Related Macular Degeneration

Yong Sung You, Oh Kwon (Seoul, South Korea) Purpose: To compare the efficacy of Avastina and Lucentis in Neovascular AMD of Korean in South Korea. Materials and Methods: Retrospective, comparative study by reviewing the medical records of patients with wet AMD who were treated with anti-VEGF and followed up more than 6 months from January 2007 to November 2009. Results: 105 eyes (105 patients) were included. Avastin was injected in 32 eyes...

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Intravitreal Injection of Tissue Plasminogen Activator (TPA) and Gas C3F8 for the Management of Large Submacular Hemorrhage

Evangelia Papavasileiou, S. Liazos, Timothy Jackson (London, UK) Advantages: To describe the safety and efficacy of intravitreal TPA and C3F8 for the management of extensive sub macular hemorrhages (SMH), associated with AMD related choroidal neovascularisation (CNV) or Idiopathic Polypoidal Choroidal Vasculopathy (IPCV). Methods: Consecutive case series of 7 patients, presenting with acute SMH from neovascular AMD (N = 5) and IPCV (N =...

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Risk Factors for Recurrent Submacular Hemorrhage in Neovascular, Age-Related Macular Degeneration

June-Gone Kim, Sung Jae Yang, Jong Uk Hwang, Soo Geun Joe, Joo Yong Lee (Seoul, South Korea) Advantages: To describe the clinical characteristics and risk factors of recurrent, submacular hemorrhage in AMD. Methods: We reviewed the medical records of the neovascular AMD patients showing submacular hemorrhage at their onset. The required minimum follow-up period was 24 months, and any newly developed, submacular hemorrhage larger than one...

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Intravitreal Bevacizumab in Age-Related Macular Degeneration as a Rescue Therapy: Two-Year Results

Montserrat González-Sastre, Ignasi Jurgens, Rosa Sust-Ferrer (Barcelona, Spain) Purpose: To report the 2-year visual and anatomical outcomes in patients treated with intravitreal bevacizumab for neovascular age-related macular degeneration (AMD) in patients who failed after photodynamic therapy (PDT) or were not eligible to that treatment. Methods: Prospective, nonrandomized, open-label study of 114 eyes of 88 patients with AMD. We...

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Intravitreal Ranibizumab for Neovascular Age-Related Macular Degeneration

Ebru Demet Aygit, Çigdem Altan, Hülya Güngel (Istanbul, Turkey) Advantages: This study reports clinical outcomes of intravitreal Ranibizumab treatment for choroidal neovascularization (CNV) due to age-related macular degeneration (AMD) and to identify predictive factors that may influence visual acuity (VA) outcomes. Methods: Thirty-one patients (32 eyes) with CNV were followed up at least 6 months after intravitreal injection (0,5 mg)...

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Macular Drusen, Atrophic AMD and Progression into Wet AMD

http://www.evrs.eu/medias/2010/congress/Age-Related-Macular-Degeneration-2.flv Ivan Fiser (Prague, Czech Republic) Advantages: 1. We find useful to carefully follow up eyes with atrophic AMD and macular drusen. Not only the drusen, but also the fading of drusen, and the conversion to geographic atrophy can be a prologue to CNV. The combination of OCT and FA, together with other usual examination methods, can distinguish between...

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Surgical Treatment of Early AMD (drusen) with Vortex Vein Occlusion: 4 to 6 Years Follow Up of a Pilot Study

http://www.evrs.eu/medias/2010/congress/Age-Related-Macular-Degeneration-2.flv Richard Luscan (Paris, France) Advantages: There is extensive literature about the vascular component of the etiopathogenesis of AMD. Lutty brought histopathological evidence that in wet AMD, choriocapillaris (CC) disturbances precede RPE atrophy (2009). Bonnet was the first to perform Vortex Vein Occlusion (VVO) for wet forms of AMD in 17 human eyes (1983)....

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Is It Reasonable to Treat End Stages of the Wet AMD?

http://www.evrs.eu/medias/2010/congress/Age-Related-Macular-Degeneration-2.flv Piotr Fryczkowski (Warsaw, Poland We would all have hope, when a doctor says: “There is a treatment for you”. But what we can offer to the 85 years old lady with huge a neovascular membrane which is so big that it goes from the superior to inferior temporal arcades? Obviously we can’t measure visual functions of such a debilitated eye. Can we improve vision...

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Macular Translocation versus Autologous RPE and Choroid Transplantation for Exudative ARMD: Indications and Prognostic Factors

http://www.evrs.eu/medias/2010/congress/Age-Related-Macular-Degeneration-2.flv Barbara Parolini, Grazia Pertile (Verona, Italy) Advantages: Exudative AMD may benefit from different surgical approaches, when the standard of care is not successful. The efficacy of macular translocation or autologous RPE and choroid transplantation is linked to specific prognostic factors. The knowledge of the prognostic factors may guide the indications for...

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Full Macular Translocation for CNVM Secondary to ARMD, Not Responding to Anti-VEGFs

http://www.evrs.eu/medias/2010/congress/Age-Related-Macular-Degeneration-2.flv] Hassan Mortada (Cairo, Egypt) Advantages: Full macular translocation (FMT) has the advantages of complete removal of CNVMs not responding to repeated anti-VEGF intravitreal injections, reposition of the macular area over healthy retinal pigment epithelium and choriocapillaris and restoration of the normal macular configuration and function. Methods: The last...

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Epimacular Brachytherapy for Established Wet Age-Related Macular Degeneration: Interim Results

http://www.evrs.eu/medias/2010/congress/Age-Related-Macular-Degeneration-2.flv Timothy L. Jackson, Pravin Dugel, Robert Petrarca, Jeff Nau for the MERITAGE study group (London, UK) Advantages: Radiation has the potential to eliminate the proliferating endothelial cells, fibroblasts, and inflammatory cells that cause vision loss in wet age-related macular degeneration (AMD), and may therefore produce a more durable therapeutic effect than...

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PDT Low Fluence: Spectral Domain OCT

http://www.evrs.eu/medias/2010/congress/Age-Related-Macular-Degeneration-2.flv Guy L’Helgoual’ch (Brest, France) Advantages: Early evaluation with spectral domain OCT of the anatomical modifications of the various retinal layers after PDT, illustrates the need for adjuvant therapy. Methods: Standard parameters were used with respect to Visudyne dose, perfusion, wash out duration, and diode laser power setting. Low fluence was...

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Core Vitrectomy Using Intrector Combined with Bevacizumab in the Treatment of Choroidal Neovascularization in AMD

http://www.evrs.eu/medias/2010/congress/Age-Related-Macular-Degeneration-2.flv Slawomir Cisiecki (Lodz, Poland), Maciej Bednarski (Lodz, Poland), Michael Koss (Frankfurt am Main, Germany), Janusz Michalewski (Lodz, Poland) Advantages: The aim of combined treatment in cases of exudative ARMD is to reduce the rate of anti-VEGF injections. Core vitrectomy using intrector is indicated when there is no response after three monthly intravitreal...

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RPE Tears and Relation with Anti-VEGF Therapies

http://www.evrs.eu/medias/2010/congress/Age-Related-Macular-Degeneration.flv Sengul C. Ozdek, Sibel Eryigit, Berati Hasanreisoglu (Ankara, Turkey) Purpose: To document the incidence of RPE tears after anti-VEGF therapy. Methods: The reports of patients with wet ARMD treated with anti-VEGFs were reviewed for occurrence of RPE tears. Lesion type, the type of anti-VEGF used and prognosis after RPE tear were analyzed. Results: A total of 538...

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Tailored Avastin in Wet ARMD

http://www.evrs.eu/medias/2010/congress/Age-Related-Macular-Degeneration.flv Ivan Fiser, Frantisek Benda (Prague, Czech Republic) Advantages: Therapy with Avastin, fully tailored to the finding, can reduce the number of injections. The “saturation phase” of the traditional treatment scheme consisting of three monthly injections is not necessary in all cases. We always adapt the treatment to the course of the disease and keep the...

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Long-Term Clinicodiagnostic Correlations of CNV Treated with Bevacizumab on Demand

http://www.evrs.eu/medias/2010/congress/Age-Related-Macular-Degeneration.flv Janusz Michalewski, Slawomir Cisiecki, Krzysztof Dziegielewski, Zbigniew Pikulski, Dominik Odrobina, Jerzy Nawrocki (Lodz, Poland) Advantages: To describe and analyze morphological changes in the retina of patients treated on demand with intravitreal bevacizumab for more than 18 months. Methods: Patients with exudative AMD were treated when activity of CNV in...

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Management of Massive Suprachoroidal Hemorrhage after Intravitreal Bevacizumab Combined with Photodynamic Therapy in Neovascular, Age-Related Macular Degeneration

http://www.evrs.eu/medias/2010/videos/SooGeunJoe_VP6_768K.flv Soo Geun Joe, Jong Uk Hwang, Joo Yong Lee, June-Gone Kim (Seoul, South Korea) Advantages: The authors will discuss their successful management of massive suprachoroidal hemorrhage with secondary angle closure glaucoma, which developed after photodynamic therapy (PDT) combined with intravitreal bevacizumab injection (IVB) for age-related macular degeneration (ARMD). In this...

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Efficacy of Avastin Intravitreal Administration for Exudative

[fhttp://www.evrs.eu/medias/2010/congress/Age-Related-Macular-Degeneration.flv Ihor Novytskyy, Tetiana Smal, Markijan Novytskyy (Lviv, Ukraine) Advantages: Intravitreal administration of Avastin for exudative ARMD is cheap, effective and safe procedure. Methods: We have observed 147 patients (243 eyes) with wet ARMD, 68 females and 79 males, mean age 68 (52 to 87) years. 1 or 2 injections of Avastin were administered to 99 patients (168...

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Loading with Lucentis, Maintenance with Avastin: Can we Maintain the VA?

http://www.evrs.eu/medias/2010/congress/Age-Related-Macular-Degeneration.flv Sengul C. Ozdek, Sibel Eryigit, Berati Hasanreisoglu (Ankara, Turkey) Purpose: To determine if PRN Bevacizumab can maintain the visual acuity (VA) gained with loading Ranibizumab for wet ARMD. Methods: The reports of patients with wet ARMD treated with 3 monthly Ranibizumab followed by PRN Bevacizumab were reviewed retrospectively. VA and central foveal thickness...

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Three Year Results in Patients with Exudative Age-Related Macular Degeneration Using Constant Interval Dosing with Ranibizumab

http://www.evrs.eu/medias/2010/congress/Age-Related-Macular-Degeneration.flv Mark E. Hammer, W. Sanderson Grizzard, Ivan J. Suner (Tampa, FL, USA) Advantages: Unlike the patients in the HORIZON study who lost vision after 2 years when they were switched to PRN dosing, our patients maintained their vision over three years. The recurrence rate in the PrONTO trial was 91.9%. Since recurrences cause visual loss, prevention of recurrences by...

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Series of Three Ranibizumab Injections for the Treatment of Retrofoveolar Neovascular Age-Related Macular Degeneration, Two and a Half-Year Follow-Up

http://www.evrs.eu/medias/2010/congress/Age-Related-Macular-Degeneration.flv Corinne Gonzalez (Toulouse, France) Advantages: Effective, efficient – Good functional results with same or less injections than protocol studies – secure but less restrictive follow-up – less recurrences, – more retinal protective, – lastly cheaper. Methods: 92 eyes of 81 patients, 25 men, 56 women, with retrofoveolar...

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Treatment of Wet Age-Related Macular Degeneration – Avastin, the One and Only?!

http://www.evrs.eu/medias/2010/congress/Age-Related-Macular-Degeneration.flv Biljana Rascanin Draganic, Miroslav Vukosavljevic (Belgrade, Serbia) Advantages: Treating patients with wet AMD in a cost-effective way. Methods: 47 patients with wet AMD (diagnosed with fluorescein angiography-FA and optical coherent tomography-OCT) were given 3 monthly doses of 1.25 mg Avastin intravitreally, and were retreated as needed. All the patients were...

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Use of High Definition OCT in Assessing the Effectiveness of Ranibizumab Intravitreal Injections in Patients with Exudative Age-Related Macular Degeneration

http://www.evrs.eu/medias/2010/congress/Age-Related-Macular-Degeneration.flv Igor A. Malov, Sergey V. Nosov, N.S. Ponomaryova (Ekaterinburg, Russia) Advantages: Use of high definition OCT gives possibilities of better assessment of all retina layers after intravitreal Ranibizumab injections in patients with exudative Age-Related Macular Degeneration (ARMD). Methods: 10 eyes of 10 patients with wet ARMD were investigated. FAG confirmed...

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Spectral Domain OCT Determinants of Active Neovascular Membrane

http://www.evrs.eu/medias/2010/congress/Age-Related-Macular-Degeneration.flv Janusz Michalewski, Slawomir Cisiecki, Krzysztof Dziegielewski, Zbigniew Pikulski, Dominik Odrobina, Jerzy Nawrocki (Lodz, Poland) Advantages: To describe different signs of active CNV presented by Spectral domain OCT examination. Methods: Retrospective, descriptive analysis of patients treated “on demand” with repeated intravitreal injections of bevacizumab...

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Correlation between Morphologic Features on Spectral-Domain Optical Coherence Tomography and Autofluorescence in Patients with Neovascular Age-Related Macular Degeneration Treated with Intravitreal Ranibizumab

http://www.evrs.eu/medias/2010/congress/Age-Related-Macular-Degeneration.flv Evangelia Papavasileiou, S. Sivaprasad, S. Liazos, I. Vasiliadis (London, UK) Advantages: To assess the relationship of the pattern of fundus autofluorescence (FAF) with the size of the lesion, the type of neovascular complex, the macular retinal thickness and the integrity of the photoreceptor inner segment – outer segment (IS/OS) juction, or/and the...

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Non-Exudative Age Related Macular Degeneration

Francesco Boscia (Bari, Italy) Approximately 80% to 90% of cases of age-related macular degeneration (AMD) are dry AMD (or non-neovascular AMD). Among those cases, 12-20% progresses to geographic atrophy (GA) and severe visual loss. To date, no medical or surgical treatment is available for this condition, however vitamin supplements with high doses of antioxidants, lutein <http://en.wikipedia.org/wiki/Lutein> and zeaxanthin...

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Sub-Classification of Exudative Age-Related Macular Degeneration Based on Anti-VEGF Response

http://www.evrs.eu/medias/2010/congress/Age-Related-Macular-Degeneration.flv Mark H. Nelson (Winston Salem, NC, USA) Advantages: A new classification for Exudative Age-Related Macular Degeneration (ARMD) is based on the clinical response to anti-VEGF medication. ICG video angiography reveals the choroidal nature of this pathological process and is used to predict the clinical response and create a strategy for sustainable vision...

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PPV in Acute Submacular Hemorrhage (Case Report)

Authors: Lidmila Prochazkova, Martina Zavorkova, Martin Hovorka, Usti Nad Labem, Czech Republic Advantages: To diminish the central scotoma and to improve the visual acuity. Methods: Two days after an acute subretinal hemorrhage, PPV with retinotomy, drainage and SF6 tamponade was performed. Effectiveness / Safety: Subjectively significant diminishing of the central scotoma and improving of the visual acuity from 2/50 to 5/50 was reached....

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Changes in Aqueous VEGF and PEDF after Ranibizumab Alone or Combined with Verteporfin for Exudative Age-Related Macular Degeneration

Authors: Jae Kyoun Ahn, Hyung Jin Moon, Yong Hwa Kim, South Korea Advantages / Purpose: To investigate changes in aqueous VEGF and PEDF in patients with subfoveal choroidal neovascularization (CNV) secondary to age-related macular degeneration (AMDCNV) after ranibizumab monotherapy or combining ranibizumab with photodynamic therapy (PDT). Methods: We recruited consecutive thirty-four patients with AMD-CNV and 10 controls. Baseline...

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To Combine or not to Combine Treatments in AMD: Is it a Matter of Savings ?

Authors: Begoña Pina Marín, José Juan Escobar Barranco, Manel Fernandez Bonet, Barcelona, Spain Advantages: The initial approach with combined therapies diminishes the need for retreatments without relinquishing gain of visual acuity (VA). This study compares two combined approach strategies to help to assess which one yields a greater VA gain, VA maintenance, OCT diminishing and rate of pretreatments. Methods: 36 patients have been...

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Full Macular Translocation for Massive Submacular Hemorrhage Secondary to Neovascular AMD

http://www.evrs.eu/medias/2009/congress/Hemorrhages.flv Author: Hassan Mortada, Cairo, Egypt Advantages: In eyes with massive submacular hemorrhage secondary to neovascular AMD, perform full macular translocation (FMT) remove the submacular hemorrhage, excise the neovascular membrane and translocate the macula to an area with healthier RPE/CC complex. This results in improvement of both distant and reading vision and prevents recurrence of...

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Temporal Peripheral Retinotomy for Evacuation of Submacular Hemorrhage Secondary to Arterial Macroaneurysm

http://www.evrs.eu/medias/2009/congress/Hemorrhages.flv Author: Hassan Mortada, Cairo, Egypt Advantages: Evacuation of submacular hemorrhage, secondary to arterial macroaneurysm, through a peripheral temporal retinotomy ensure rapid and complete removal of the submacular hemorrhage. This helps to prevent the toxic effect of the blood on photoreceptors with subsequent preservation of visual acuity. Experience from full macular translocation...

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Surgical Displacement of Medium-Sized Submacular Hemorrhage

http://www.evrs.eu/medias/2009/congress/Hemorrhages.flv Author: Sophie J. Bakri, Rochester, MN, USA Advantages: Surgical displacement of medium-sized thick submacular hemorrhage has the advantage of minimizing the toxic effects of blood on the retina. Methods: Pars plana vitrectomy, subretinal tPA and air-fluid exchange is performed. The patient lies flat on his back for 30 minutes, then upright for the next 24 hours. Effectiveness /...

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Submacular Hemorrhage: a Lost Eye?

http://www.evrs.eu/medias/2009/congress/Hemorrhages.flv Authors: Rossi Pietro, Claudia Castiglioni, Carlandrea Trillo, Genoa, Italy Submacular bleeding represents one of the worse end points in the evolution of age related degeneration. The aim of this investigation was to evaluate if displacement of the blood associated with anti-VEGF therapy or a RPE-choroid patch could yield a better functional outcome. Material and methods: 19 eyes of...

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Surgical Treatment of Submacular Hemorrhage

http://www.evrs.eu/medias/2009/congress/Hemorrhages.flv Authors: Grazia Pertile, Barbara Parolini, Verona, Italy Advantages: The treatment of submacular hemorrhage may benefit from different treatments on the bases of the hemorrhage’s area and location. Methods: Submacular hemorrhages located only under the retina and not under the retinal pigment epithelium (RPE) and involving an area within the arcades, were treated with intravitreal...

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An Atraumatic Method of Submacular Hemorrhage Management

http://www.evrs.eu/medias/2009/congress/Hemorrhages.flv Author: Aslanova Veronika, Odessa, Ukraine Advantages: Pneumatic displacement of SMH with intravitreal perfluoropropane without tPA allows clearing of the macular area from subretinal blood and achieves visual recovery in the short term. The procedure is atraumatic and cost-effective. Methods: Retrospective, noncomparative, interventional case series. The results of submacular...

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Macular Translocation with 360-Degree Retinotomy for the Managment of Retinal Pigment Epithelial Tear: 3 Years Results

http://www.evrs.eu/medias/2009/congress/Surgery.flv Authors: Barbara Parolini, Grazia Pertile, Verona, Italy To determine whether macular translocation with 360-degree retinotomy can stabilize and / or improve visual acuity in patients with retinal pigment epithelium (RPE) tear, given the increasing number of reports on this complication following vascular endothelial growth factor (VEGF)-modulating therapy. Methods: Prospective...

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Submacular Surgery for Myopic Choroidal Neovascular Membrane

http://www.evrs.eu/medias/2009/congress/Surgery.flv Author: Khaled El Rakhawy, Cairo, Egypt Advantages: In selected cases of myopic CNVM, surgical removal gives better visual outcome and relieves the patient from metamorphopsia as well as from the need to have many repeated injections with only limited improvement or merely stabilization of vision. Large membranes are particularly suitable for this approach. Methods: After complete...

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There Could Still Be a Place for Surgical CNV Removal

http://www.evrs.eu/medias/2009/congress/Surgery.flv Author: Klaus Lucke, Bremen, Germany Introduction: Surgical removal of subfoveal CNVs was practiced widely in the 1990s for the treatment of AMD and other exudative maculopathies. Since it virtually always left a large subfoveal RPE defect the visual results were by and large disappointing and the Submacular Surgery Trial (SST) showed that no statistically significant improvement in vision...

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Is Surgical Ablation of Blood Neovessels Still Useful?

http://www.evrs.eu/medias/2009/congress/Surgery.flv Author: Jean-Paul Amar, Cannes, France Subretinal surgery has slowly disappeared but 75% of eyes with a subretinal heamatoma are lost. The subretinal drainage of the blood and the surgical ablation of the blood neovessels seem to remain still useful with a quite low rate of complications.

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Epimacular Brachytherapy for Wet AMD: 24 Months Results

http://www.evrs.eu/medias/2009/congress/Surgery.flv Authors: TL Jackson, M Farah, JP Duprat, M Avila, GY Fujii, J Rossi, A Santos, R Palank , J Nau, London, UK Advantages: Epimacular brachytherapy (EMB) offers a novel, durable, costeffective treatment for age-related macular degeneration. Methods: Patients with classic, mixed or occult choroidal neovascularisation (CNV) underwent a pars plana vitrectomy followed by 24 Gy beta irradiation...

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Combined Treatment of Retinal Pigment Epithelium Serous Detachment in the Macular Region Caused by Age-Related Macular Degeneration

http://www.evrs.eu/medias/2009/congress/Surgery.flv Authors: Victor N. Kazaykin, Igor A. Malov, Yekaterinburg, Russia Advantages: Combination of laser retinopuncture and 25G endovitreal surgery provides a possibility to obtain attachment of retinal pigment epithelium serous detachment (RPE SD), caused by ARMD, in the macular region in its combination with posterior hyaloid detachment. Methods: After limiting retinal lasercoagulation at...

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Spectral OCT Determined Anti-VEGF Treatment

http://www.evrs.eu/medias/2009/congress/When-Re-Treating.flv Authors: Janusz Michalewski, Slawomir Cisiecki, Dominik Odrobina, Krzysztof Dziegielewski, Zbigniew Pikulski, Zofia Michalewska, Maciej Bednarski, Jerzy Nawrocki, Lodz, Poland Advantages: Spectral domain OCT determined anti- VEGF therapy enabled the reduction of number of injections. Moreover Spectral OCT enabled to determine some prognostic factors for anti- VEGF...

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Assessment of CNV Activity with a New Activity

http://www.evrs.eu/medias/2009/congress/When-Re-Treating.flv Authors: Sengul Ozdek, Cuneyt Ozmen, Berati Hasanreisoglu, Ankara, Turkey Advantages: A new activity scoring (AS) for assessment of the neovascular ARMD activity is defined. AS supplies standardization for the assessment of the lesion activity after anti-VEGF therapy. Methods: 52 eyes with neovascular ARMD treated with anti- VEGF agents were involved. The AS is based on 1) fluid...

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