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Efficacy of PDT in Steroid-associated CSCR: A Case-control Study

Purpose: Corticosteroid exposure has previously been suggested as a risk factor for the development of chronic central serous chorioretinopathy (CSC). In this study we assess whether the therapeutic outcome of half-dose photodynamic therapy (PDT) is different in CSC patients with prior exogenous corticosteroid use or endogenous hypercortisolism as compared to patients without any corticosteroid exposure. Methods: We retrospectively...

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PDT for CSCR: What is the Appropriate Dose?

Purpose: Visudyne is FDA-approved for management of exudative AMD but is probably much more commonly used off-label. According to the manufaturer’s label “Visudyne is not approved for use in other indications, in combination with another product, with reduced fluency, or with any other alteration to administration.” Both for exudative AMD and central serous chorioretinopathy photodynamic therapy with Visudyne is often...

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Full PDT for CSCR

Purpose: We present 7 cases with Central Serous Chorioretinipathy with more than 6 months of evolution. Methods: All of them were treated with Photodynamic Therapy at full dose of 50 J/cm2 and 6 mg/m2. All the patients were visited at 1, 3, 6 and 12 months, only 3 of them came to the 24 month visit. Results: In 6 cases the liquid disappeared completely and in 1 case persisted although it decreased and a better vision was registered. No...

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Half-fluence PDT in the Treatment of Chronic CSCR

Purpose: We carried out a retrospective chart review of all patients with chronic CSC involving the fovea treated with HF-PDT and followed-up at least for 6 months. Methods: Recorded parameters included Best-Corrected Visual Acuity (BCVA) in logMAR, Central Subfield Thickness (CST) by Cirrus OCT and any adverse event occurred at baseline and during follow-up visits. 23 eyes of 23 patients were included. Results: Mean follow-up time (SD,...

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Chronicity and Recurrence Impact in CSCR After PDT

Purpose: To analyse the influence of chronicity and recurrence in structural and functional outcomes in central serous chorioretinopathy (CSC) patients who had half-dose photodynamic therapy (PDT), and to determine the characteristics of patients that recurred after treatment. Methods: A retrospective, observational study included treatment-naïve patients with CSC who received half-dose PDT. Measurements of best-corrected visual acuity...

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Short & Long-term Functional & Anatomic Changes After Half-dose PDT for CSCR

Purpose: To evaluate short and long-term functional and structural changes after half-dose photodynamic therapy (PDT) for central serous chorioretinopathy (CSC) and assess the prognostic effect of episode duration and history of previous episodes. Methods: A retrospective study including acute and chronic CSC treatment-naïve patients submitted to half-dose PDT and followed for at least 6 months. Best corrected visual acuity (BCVA), mean...

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