European VitreoRetinal Society a certain philosophy

http://www.dailymotion.com/video/xudsd8 http://www.dailymotion.com/video/xuf2lx Advantages: Intravitreal triamcinolone injections turned out to be effective in reducing macular edema and improving vision in refractory DME after a laser treatment or even as an initial treatment. The steroid-related adverse events, e.g. cataract and elevated intraocular pressure, should be weighed against the benefits of the treatment. Methods: Twenty-mg...

http://www.dailymotion.com/video/xudsd8 http://www.dailymotion.com/video/xuf2lx Persistent diffuse macular edema (ME) or cystoid ME is a result of chronic inflammation with the generalized breakdown of the inner blood retinal barrier and fluid accumulation, primarily in the outer plexiform layer. This process is characterized by the development of hard exudates and progressively lost of vision. Triamcinolone acetonide is the most effective...

http://www.dailymotion.com/video/xudsd8 http://www.dailymotion.com/video/xuf2lx Advantages: Use of intravitreal injection of crystalline corticosteroids- bethamethasone and triamcinole dose of 4 mg in 0.1 ml allows to improve visual acuity and restore adequate morphological retinal thickness in patients with diffuse diabetic macular edema. Methods: Comparison of efficacy and safety of intravitreal injection of 4 mg (0.1 mL) triamcinolon...

http://www.dailymotion.com/video/xudsd8 http://www.dailymotion.com/video/xuf2lx Advantages: Given the chronic nature of diabetic macular edema (DME), an implant (ILUVIEN®) that releases a continuous, submicrogram daily dose of fluocinolone acetonide (FAc) could fill an unmet need for continuous long-term therapy. Methods: The Fluocinolone Acetonide in Diabetic Macular Edema (FAME) study consisted of 2 randomized, prospective, multicenter,...

http://www.dailymotion.com/video/xueopo Advantages: Combined treatment of diffuse diabetic macular edema using intravitreal injection of bethamethasone and laser coagulation is effective in improving visual acuity and restoration of the morphofunctional state of the retina. Methods: Intravitreal injection 4 mg (0.1 ml) of bethamethasone combined with laser coagulation was conducted in 33 patients (33 eyes) with diffused diabetic macular...

http://www.dailymotion.com/video/xukzpn http://www.dailymotion.com/video/xuk625 Ozurdex®, a dexamethasone (DEX) intravitreal implant, has been shown in randomized controlled trials to reduce macular edema and improve visual acuity in patients with either branch retinal vein occlusion (BRVO) or central retinal vein occlusion (CRVO). However, repeated injections are usually necessary, particularly for CRVO patients. And the long-term adverse...

Advantages: Combined treatment with sub-Tenon’s injection of triamcinolone and intravitreal anti-VEGF injection has beneficial effect in improving visual acuity and anatomic outcomes in refractory neovascular AMD patients. Methods: Seven eyes of 7 patients with refractory neovascular age-related macular degeneration (AMD) secondary to polypoidal choroidal vasculopathy (PCV) were enrolled. Refractory PCV was defined as no response of...

http://www.evrs.eu/medias/2010/congress/Non-Proliferative-Diabetic-Maculopathies.flv Gungor Sobaci, Cuneyt Erdurman, A. Hakan Durukan (Ankara, Turkey) Purpose: Controversy exists in the literature regarding the most appropriate method of treatment in diabetic macular edema. We aimed to find out the current best care for selected group of patients who had untreated, acute, and diffuse diabetic macular edema. Methods: Patients with acute DDME...

http://www.evrs.eu/medias/2010/congress/Non-Proliferative-Diabetic-Maculopathies.flv Siamak Moradian, Amir Faramarz, Qiumars Heidari, Masoud Salehipoor, Mohammad Mohammadzadeh (Tehran, Iran) Advantages: To compare the results of IVT vs IVB vs sham injections at the end of phacoemulsification (PE) on diabetic macular edema (DME). Methods: In a RCT 88 diabetic patients with at least moderate NPDR were undergone one of the 3 injections, IVT...

Nataliya M. Kislicyna, S.V. Novikov, S.V. Belikova (Moscow, Russia) Advantages: One of the current questions in vitreous surgery is the visualization of vitreous body and the identification of semi-transparent epiretinal membranes and internal limiting membrane. Peyman was the first to report on the use of triamcinolone acetonide as an aid to visualize the vitreous and posterior hyaloid during vitrectomy. The water- insoluble triamcinolone...

http://www.evrs.eu/medias/2010/congress/Branch-Retinal-Vein-Occlusion-Central-Retinal-Vein-Occlusion.flv Alireza Ramezani, Morteza Entezari, Siamak Moradian, Hamed Esfandiari, Babak Dehsarvi, Masoud Soheilian, Hamid Ahmadieh, Mehdi Yaseri (Tehran, Iran) Advantages: Repeated intravitreal injections of bevacizumab (IVB) are more effective than repeated intravitreal injections of triamcinolone (IVT) in acute retinal vein occlusion...

Kubilhan Elmas, Özgür Bilen, Ali Altýnsoy (Ankara, Turkey) Purpose: To evaluate the efficacy of intravitreal triamcinolone injection in eyes with macular edema due to branch retinal vein occlusion (BRVO) over a 1-year period. Methods: The authors performed a retrospective chart review of 18 eyes of 18 patients (mean age 71 years) who underwent intravitreal injections with 2 mg triamcinolone acetonide and 1,25 mg bevacizumab for macular...

Osman Çekiç, M. Selim Kocabora, Nilay Kandemir (Istanbul, Turkey) Advantages: To assess the effectiveness of intravitreal triamcinolone and combined triamcinolone-bevacizumab injection as adjunctive treatment to grid laser for diffuse diabetic macular edema. Methods: Sixty-nine eyes of 69 patients (29 male, 40 female) with diffuse diabetic macular edema were intravitreally injected either with 4mg/0.1ml triamcinolone (n = 29) or...

Ozgür Bilen, Kubilhan Elmas, Ali Altýnsoy (Ankara, Turkey) Purpose: To assess the long-term safety and efficacy of intravitreal triamcinolone acetonide injection in the management of macular edema caused by branch retinal vein occlusion. Methods: This retrospective case series included 11 patients (11 eyes) with retinal vein occlusion and macular edema. They received an intravitreal injection of 4 mg triamcinolone acetonide. Follow-up...

http://www.evrs.eu/medias/2010/videos/MohamedElDeeb_2_VP6_768K.flv Mohamed El-Deeb (Cairo, Egypt) Advantages: A lot of dyes are used to help ILM peeling. All of them carry the risk of retinal toxicity. This video shows that triamcinolone acetonide (which is very safe) can be used effectively as an alternative tool to the commonly used dyes. Methods: After doing core vitrectomy, non-preserved triamcinolone acetonide is injected in the...

http://www.evrs.eu/medias/2010/congress/Proliferative-Diabetic-Retinopathy.flv Arwa Azmeh, Judi Abdin (Damascus, Syria) Advantages: To evaluate the efficacy of intravitreal triamcinolone acetonide injection (IVT) in causing regression of new vessels activity in proliferative diabetic retinopathy (PDR) refractory to pan retinal photocoagulation (PRP). Methods: 11 eyes of 10 patients with type 2 diabetes and active PDR refractory to PRP...

http://www.evrs.eu/medias/2010/congress/Vascular-Pathologies-in-Young-Patients.flv Ihab Saad Othman, Magdy Moussa, Manal Bouhaimed (Giza, Egypt) Advantages: Coats disease is associated with vascular leaky telangiectatic vessels. Intravitreal triamcinolone injection modulates leaking vessels and is associated with subretinal fluid resorption that can be followed by laser peripheral photoablation. Methods: Retrospective, interventional case...

Authors: Elmas Kubilhan, Bilen Özgür, Arsen Akýncý, Ersel Özkýlýç, Ali Altýnsoy, Ankara, Turkey Advantages / Purpose: To study the effect of Cataract Surgery with Bevacizumab alone and Combined with Intravitreal triamcinolone Injection on Progression of Diabetic Retinopathy. Setting: Kudret Eye Hospital, Ankara. Methods: Cataract surgery with phacoemulsification was performed in 52 eyes of 44 patients who had diabetic retinopathy....

Authors: Dong Hyun Jee, Sang Hee Doh, Suwon City, Kyoungki Province, South Korea Advantages: Effects of intrvitreal ranibizumab injection are more efficient than intravitreal triamcinolone injection on non-ischemic macular edema of BRVO. Methods: In a prospective randomised clinical trial, 50 eyes of 50 patients with non-ischemic macular edema of BRVO were included. Eligible eyes were assigned to 0.05mg ranibizumab(25 eyes) or 0.05cc...

Masih Hashemi, Roshanak Aliakbar Navahi, Khalil Ghasemi Falavarjani Advantages: In this double-blind randomized clinical trial study, we compared safety and effectiveness of intravitreal Triamcinolone Acetonide (TA) versus Avastin in patients with Clinically Significant Macular Edema (CSME). Methods: Four mg TA was injected in 28 eyes and 1.25 mg Avastin was injected in 23 eyes of patients with CSME. The visual acuity, intraocular pressure,...

I.A. Malov, O.A. Ulasevich, K.G. Naumov (State Institution “IRTC Eye Microsurgery” named after S.N. Fyodorov Ekaterinburg Branch, Ekaterinburg, Russia) Advantages: Forecast of visual outcome of intravitreal kenalog injection for cystoid macular edema(CME) caused by retinal veins occlusion using OCT provide a possibility to optimize indications for this procedure. Methods: A retrospective study of 13 patients (13 eyes) with cystoid...

Marco Dal Vecchio, Valeria Russo, Sara Tonetti Advantages: IVT Micronized during sutureless vitrectomy allows observing the posterior Hyaloid and the vitreous base. In the video shows the differences between IVT Micronized and traditional Triamncinolone. Methods: The video shows the different uses of IVT micronized and the simultaneous injection of IVT and Triamcinolone. A preliminary report of cases of Sutureless Transconjunctival 25...

Osman Cekic, Mehmet Cakir, Omer F. Yilmaz Advantages: To report the usefulness of serial optical coherence tomography (OCT) follow-up of a case with retinal pigment epithelial (RPE) tear after intravitreal bevacizumab injection for serous pigment epithelial detachment (PED) from neovascular age-related macular degeneration (AMD). Methods: An 80-year-old woman underwent 1.25 mg intravitreal bevacizumab treatment for serous PED secondary to...

Osman Cekic, Mehmet Cakir, Cengiz Alagoz, Nese Alagoz, Omer F. Yilmaz Advantages: To demonstrate the effectiveness of triple therapy in patients with subfoveal choroidal neovascular membrane (SCNM) related to age-related macular degeneration (AMD). Methods: Twenty-nine eyes of 26 patients (10 male, 16 female, mean age: 71.2 years) with SCNM that underwent triple therapy were evaluated retrospectively. Intravitreal injection of 2 mg...

Díez Villalba, Rosario, Mora de Oñate Javier, Rodriguez Márquez, María Trinidad, Izquierdo Vázquez Cristina, Alvarez Holgado Marta, Hita Antón César We present four cases of cystoid macular edema (CME) secondary to retinal telangiectasia: 1 case of Coats disease (adult form), 2 cases of unilateral macular telangiectasia (type 1) and 1 case of bilateral macular telangiectasia (type 2). Three cases were treated with intravitreal...

Ben Yahia S, Jenzeri S, Hmidi K, Attia S, Zaouali S, Khairallah M Purpose: To compare response after intravitreal bevacizumab (IVB) or triamcinolone (IVT) in diabetic macular edema with severe hard exudates. Methods: Forty-eight eyes were randomly assigned to either IVB or IVT. Follow-up was > 6 months. Results: There was significant improvement in BCVA in the IVT group when compared with the IVB group (P= .04). Complete resolution of...

http://www.evrs.eu/medias/2008/congress/Combined-Intravitreal-Bevacizumab-and-Triamcinolone-Acetonide-for-the-Treatment-of-Acute-Non-Arteritic-Anterior-Ischemic-Optic Neuropathy.flv Morteza Entezari, Alireza Ramezani, Hassan Ghassemi, Alireza Naderi Ophthalmic Research Center, Shaheed Beheshti University of Medical Sciences, Tehran, Iran. Purpose: To report the effect of combined intravitreal bevacizumab and triamcinolone acetonide...

Guy l’Helgoualch, MD (Brest, France) PURPOSE: To check using Avastin in intravitreous injection reduces the surface and the thickness of the neovascular membrane. To check improving the effect of PDT and reducing the side effects increases the final visual acuity. To verify this protocol of tritherapy reduces the number of treatment during the period of follow-up. METHODS: The population of patients includes the same proportion of...

Michael A. Singer, MD (San Antonio, TX), Rafael Lin Wong, (San Antonio, TX), Catherine Alderete, CMA (San Antonio, TX), Robin Hartman, BBA (San Antonio, TX) PURPOSE: To determine whether combination therapy of Avastin and Kenalog is useful in the treatment of corneal neovascularization. METHODS: A patient presenting with severe corneal neovascularization in both eyes and Hand Motion (HM) vision was given multiple treatments of Avastin, by...

Albert J. Augustin, MD (Sulzfeld, Germany), Indre Offermann, MD (Karlsruhe, Germany), Stephan Puls, MD (Karlsruhe, Germany), Frank H.J. Koch, MD (Frankfurt am Main, Germany), Ursula Schmidt-Erfurth, MD (Vienna, Austria)* PURPOSE: To assess the treatment and outcome of patients with CNV treated with PDT combined with intravitreal triamcinolone (TA). METHODS: Patients (n? 307) suffering from CNV (76.2% subfoveal, 12.1% juxtafoveal, 11.7%...

http://www.evrs.eu/medias/2006/congress/Six-month-Results-of-a-Randomized,-Double-masked,-Controlled-Trial-of-Intravitreal-Triamcinolone-as-an-Adjunct-to-Photodynamic-Therapy-in-Predominantly-Classic-Neovascular-Age-related-Macular-Degeneration:-The-Canadian-RETINA-Study.swf David Maberley, MD, FRCSC, MSc (Vancouver, Canada),* PURPOSE: To compare safety data and ETDRS visual acuity outcomes data for one-hundred subjects with predominantly...

Panos Stergiou, (Thessaloniki, Greece), Kostantinos Malamos, MD (Thessaloniki, Greece), Efstathios Dragiotis, MD (Thessaloniki, Greece), Anastasios Felekidis, MD (Thessaloniki, Greece), Tania Karagiani, MD (Thessaloniki, Greece), Stavros Dimitrakos, MD (Thessaloniki, Greece) PURPOSE: To investigate whether combined intravitreal use of triamcinolone (Kenacort) and bevacizumab (Avastin) can prolong the beneficial effect and reduce the need...

http://www.evrs.eu/medias/2006/congress/The-Effect-of-Kenalog-as-Adjunctive-Treatment-to-Visudyne-in-Minimally-Classic-and-Occult-Neovascular-AMD:-A-Prospective,-Randomized-Clinical-Trial.swf Tom Sheidow, MD, FRCS(C) (London, Canada), Varun Chaudhary, MD (London, Canada), Phil Hooper, MD, FRCSC (London, Canada), Alex Mao, MD (London, Canada) PURPOSE: To evaluate the mean change is ETDRS visual acuity score from baseline and the number of...

http://www.evrs.eu/medias/2006/congress/Combined-Intravitreal-Triamcinolone-with-Photodynamic-Therapy-for-the-Treatment-of-Choroidal-Neovascularization-in-Age-Related-Macular-Degeneration.swf Catherine Favard, MD (Paris, France), Valerie Krivosic, MD (Paris, France), Lucie Machado, DO (Paris, France), Michael Assouline, MD, PhD (Paris, France), Catherine Francais, MD (Paris, France) PURPOSE: To determine whether photodynamic therapy (PDT)...

Arturo Santos, MD, PhD (Guadalajara, Mexico), Enrique A. Roig-Melo, MD PhD (Guadalajara, Mexico), Ramon Flores-Fuentes, MD (Guadalajara, Mexico), Juan C. Altamirano, MD (Guadalajara, Mexico) PURPOSE: To evaluate the feasibility and safety of the combination of photodynamic therapy with verteporfin (PDT), intravitreal Bevacizumab and preservative free Triamcinolone acetonide (PFTA) for the treatment of exudative AMD. METHODS: This is a...

Edwin H. Ryan, MD (Minneapolis, MN), Lejla Mutapcic, BS (Rochester, MN), Jose S. Pulido, MD (Chicago, IL) PURPOSE: To determine via a retrospective review of treated patients whether thermal laser photocoagulation combined with intravitreal triamcinolone (IVTA) can safely and effectively reduce the risk of neovascular membrane recurrence and vision loss in patients with choroidal neovascularization (CNV). METHODS: We conducted a...

Frank H.J. Koch, MD (Frankfurt am Main, Germany),* Albert J. Augustin, MD (Karlsruhe, Germany), Robert G. Josephberg, MD (Yonkers, NY),* K. Peter Luloh, (Sanford, FL),* Indre Offermann, MD (Karlsruhe, Germany), Shahrzad Ghozisad, MD (Frankfurt am Main, Germany), Joachim Puchta, MD (Frankfurt am Main,Germany), Pankaj Singh, MD (Frankfurt Am Main, Germany) PURPOSE: A treatment regimen that combines photodynamic therapy (PDT) with a core pars...

Michael J. Potter, MD (Vancouver, Canada),* Shelagh M. Szabo, BSc (Vancouver, Canada) PURPOSE: To compare the incidence of recurrence of CNV at 18 months after treatment with photodynamic therapy (PDT) with verteporfin, and PDT plus intravitreal Kenalog (IVT), in patients with age-related macular degeneration. METHODS: This is a prospective study of consecutive patients treated with PDT alone, or PDT plus IVT at baseline. Final treatment...

Timothy W. Olsen, MD (Minneapolis, MN),* Xiao Feng, MD (Minneapolis, MN),* Kathy Wabner, BA (Minneapolis, MN),* Stanley R. Conston, BS (Menlo Park, CA),* David H. Sierra, PhD (Menlo Park, CA),* Tom S. Chang, MD (Pasadena, CA),* Karl G. Csaky, MD PhD (Bethesda, MD), Morton E. Smith, MD (St. Louis, MO), J. Douglas Cameron, MD (Rochester, MN) PURPOSE: To describe a drug delivery system, surgical technique, safety and pharmacokinetics for...

Noha Khater, (Cairo, Egypt), Hoda, MH Mostafa, MD (Cairo, Egypt), Mahmoud Soliman (Cairo, Egypt), Tamer Macky, MD (Cairo, Egypt) PURPOSE: To evaluate the outcomes of combined intravitreal triamcinolone (IVTA) and photodynamic therapy (PDT) in the treatment of subfoveal choroidal neovascularization (CNV) caused by age related macular degeneration (AMD) and myopia. METHODS: Fifteen eyes from 15 patients with subfoveal CNV caused by AMD (n=10)...

Peter K. Kaiser, MD (Cleveland, OH)* PURPOSE: The VeriTAS study is designed to evaluate the efficacy and safety of verteporfin PDT combined with either intravitreal triamcinolone acetonide or pegaptanib sodium to treat subfoveal choroidal neovascularization (CNV) secondary to age-related macular degeneration (AMD). The 24-month randomized, double-masked VeriTAS study enrolled patients at 50 centers in the U.S. METHODS: Inclusion criteria:...

David Hauser, MD (Kefar Bilu B, Israel), Yoel Greenvald, MD (Rehovot, Israel), Amir Bukelman, MD (Rehovot, Israel), Haya Katz, MD (Rehovot, Israel), Reut Parnes, MD (Rehovot, Israel), Nir Shoham, (Rehovot, Israel), Genady Landa, MD (Rehovot, Israel), Ayala Pollack, MD (Rehovot, Israel) PURPOSE: To compare the outcome of intravitreal triamcinolone (Kenalog) and intravitreal bevacizumab (Avastin) for eyes with serous PED and occult choroidal...

http://www.evrs.eu/medias/2006/congress/Prolonged-Choroidal-Hypofluorescence-Following-Verteporfin-PDT-Combined-with-Intravitreal-Triamcinolone-Acetate-Injection-for-Agerelated-CNVM.swf Jeffrey K. Luttrull, MD (Ventura, CA), Charles A Spink, CRA (Ventura, CA) PURPOSE: To determine the incidence and effect of prolonged choroidal hypofluorescence (PCH) following combined verteporfin photodynamic therapy and intravitreal triamcinolone acetate...

Paul B. Griggs, MD (Seattle, WA), Richard C. Lee, BS (Seattle, WA) PURPOSE: To review the clinical results of sequential pegaptanib monotherapy following verteporfin photodynamic therapy for choroidal neovascularization. METHODS: Patients were identified in which pegaptanib therapy was initiated following initial treatment of choroidal neovascularization with verteporfin photodynamic therapy with or without adjuvant intravitreal...

Ajay Dudani, MD (Mumbai, India), Alay S Banker, MD (Ahmedabad, Gujarat, India), J. Fernando Arevalo, MD, FACS (Caracas, Venezuela) PURPOSE: To examine the 12-month results of a group of patients treated with combined photodynamic therapy (PDT) with verteporfin and intravitreal triamcinolone acetonide for choroidal neovascularization (CNV). METHODS: Retrospective analysis of noncomparative case series of 54 eyes with CNV which were treated...

http://www.evrs.eu/medias/2006/congress/Intravitreally-Injected-Anti-VEGF-Drugs-Exert-a-Biological-Effect-in-the-Fellow-Eye.swf Tongalp H. Tezel, MD (Louisville, KY), Charles C. Barr, MD (Louisville, KY), Henry J. Kaplan, MD (Louisville, KY) PURPOSE: To determine whether the intravitreal injection of anti-VEGF drugs (Kenalog, Macugen, Avastin) exert any biological effect in the fellow eyes of patients with bilateral exudative...

http://www.evrs.eu/medias/2006/congress/The-Value-and-Cost-effectiveness-of-Interventions-for-Subfoveal,-Neovascular,-Age-related-Macular-Degeneration-(ARMD).swf Melissa M. Brown, MD, MN, MBA (Flourtown, PA),* Gary C. Brown, MD, MBA (Wyndmoor, PA)* PURPOSE: To assess the value of interventions utilized for the treatment of subfoveal, neovascular, agerelated macular degeneration (ARMD) employing evidencebased data from clinical trials...

Gregory R. Blaha, MD, PhD (Peabody, MA), Jeffrey L. Marx, MD (Peabody, MA)* PURPOSE: To report our experience with combination low-fluence PDT. METHODS: An IRB-approved, retrospective chart review of all patients receiving low-fluence (50% standard) PDT (LFPDT) at our institution was performed. RESULTS: Twenty five eyes of 24 patients received LFPDT. Two eyes did not receive combination therapy, two received Macugen (Pegaptanib,...

Alay S. Banker, MD (Ahmedabad, India), J. Fernando Arevalo, MD, FACS (Caracas, Venezuela), Ajay Dudani, MD (Mumbai, India) PURPOSE: To determine the results of combination triple therapy for choroidal neovascularization (CNV). METHODS: Prospective pilot study of 11 consecutive eyes with new (previously untreated) CNV which were treated with photodynamic therapy (PDT) with visudyne along with intravitreal bevacizumab (1.25mg) and subtenon...