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The Combination of Trypan Blue and Brilliant Blue G-Assisted Vitrectomy for Macular Pucker: Histopathological Findings

ABSTRACT Purpose: To report on the combined use of trypan blue (TB) and brilliant blue G (BBG) for staining the epiretinal membrane (ERM) and internal limiting membrane (ILM) during vitrectomy and to describe the histopathological findings. Methods: 10 surgical specimens were removed from 10 eyes with macular pucker during vitrectomy using a commercially available combination of TB and BBG for ERM and ILM staining and peeling. Specimens...

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Internal Limiting Membrane Peeling in Macular Disorders

ABSTRACT The internal limiting membrane (ILM) is a thin, transparent, acellular membrane that forms the innermost boundary of the retina. ILM is the basal lamina of the inner retina, it is formed by the footplates of Müller cells and is composed of collagen fibers, glycosaminoglycans, laminin, and fibronectin. It has an important role in the early stages of retinal and optic nerve development, as a critical component of retinal...

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OCT-guided Induction of Posterior Vitreous Detachment for Firmly Adherent Posterior Hyaloid in Macular Surgery

ABSTRACT Purpose: Surgical Induction of posterior vitreous detachment (PVD) is an important step in vitreoretinal surgery. In some cases, it can be traumatic due to firm attachment of the posterior hyaloid to the disc, particularly when vitrectomy is performed in a young patient with adherent hyaloid or with small gauge cutters, which often require high suction levels to induce PVD. This can be complicated by retinal nerve fiber layer...

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Functional and Anatomical Outcomes of Superior Inverted Internal Limiting Membrane Flap in Macular Hole Surgery

ABSTRACT Introduction: In 2010, Michalewska et al. described the inverted ILM flap technique for large macular hole (minimum diameter 400 micras).  This technique was reported to increase the anatomical closure rates and functional results of large macular holes and myopic macular holes. Various modifications have been described since it was introduced but more studies are required to establish which technique of ILM flap achieves better...

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Inverted ILM Flap Technique for the Treatment of Chronic and Large Idiopathic MH with the Use as a Vital Dye Suspension “Vitreocontrast”

ABSTRACT Recently, inverted internal limiting membrane (ILM) flap technique has been reported to increase the anatomical closure rates of large and chronic macular holes(MH). But the technique is limited by difficulty in visualizing the flap using traditional vital dyes, its possible cytotoxic effects and relative mobility of the flap, complicating maintaining the inverted ILM flap inside the hole during fluid-air exchange with high rate of...

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Complex Macular Holes: Does Simple Vitrectomy and ILM Peeling also Work?

ABSTRACT MHS (macular hole surgery) with dye-assisted ILM-peeling is a standard procedure to treat idiopathic MHs leading to high anatomic success rates and good functional outcomes. Prognosis in case of MHs with preexisting pathologies that affect the retina or RPE, however, is uncertain. The current paper demonstrates a consecutive clinical series of atypical or secondary macular holes with coexisting retinal pathologies, such as MacTel...

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