Yuksel Totan, Fatma Betul Aydogdu, Emre Guler (Ankara, Turkey)


To evaluate the surgical experiences with Brilliant blue G (BBG) staining of the inner limiting membrane (ILM) and the outcomes of BBG assisted macular hole surgery.


In 10 patients with stage 3-4 idiopathic macular holes, BBG (Brilliant peel, Fluoron) was applied following complete posterior vitreous detachment on the macular surface under air conditions for 1 minute. Main outcome measures were staining properties, visual acuity improvement, and closure of the macular hole.

Effectiveness / Safety:

Although intraoperative BBG staining of the ILM was somewhat less intensive compared to indocyanine green (ICG) staining, it was sufficient to successfully remove the ILM in all cases. Macular hole (MH) closure was achieved in all patients. Postoperative visual acuity was improved in 8 patients and remained unchanged in 2 patients with cataract progression. Clinically, no cases of BBG toxicity were recognized.

Take home message:

BBG allowed a sufficient staining of the ILM associated with anatomical and functional improvement along with no clinical retinal toxicity after macular hole surgery.